SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4af0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		4 / 4 HIS B 110
LEU B 277
LEU B 282
LEU B 106
 None
 1.20A 1a4lD-4af0B:
5.8		 1a4lD-4af0B:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		4 / 7 MET B  88
SER B 341
SER B 343
ILE B 344
 IMP  B1527 (-4.0A)
None
IMP  B1527 (-2.6A)
None
 1.07A 1fxhA-4af0B:
undetectable
1fxhB-4af0B:
undetectable		 1fxhA-4af0B:
17.13
1fxhB-4af0B:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		4 / 8 GLY B 358
GLY B 340
ARG B 355
GLY B 338
 None
MOA  B1526 (-4.0A)
None
None
 0.77A 1jhaA-4af0B:
undetectable		 1jhaA-4af0B:
21.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		7 / 11 ASP B 288
ASN B 317
ARG B 336
MET B 339
GLY B 340
CYH B 345
GLY B 427
 MOA  B1526 (-3.3A)
MOA  B1526 ( 3.6A)
MOA  B1526 (-3.6A)
None
MOA  B1526 (-4.0A)
IMP  B1527 (-3.3A)
IMP  B1527 (-3.2A)
 1.19A 1jr1A-4af0B:
57.1		 1jr1A-4af0B:
56.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		10 / 11 ASP B 288
SER B 289
SER B 290
ASN B 317
ARG B 336
MET B 339
GLY B 340
CYH B 345
GLY B 429
GLN B 470
 MOA  B1526 (-3.3A)
MOA  B1526 (-3.9A)
MOA  B1526 (-2.6A)
MOA  B1526 ( 3.6A)
MOA  B1526 (-3.6A)
None
MOA  B1526 (-4.0A)
IMP  B1527 (-3.3A)
IMP  B1527 ( 3.3A)
MOA  B1526 ( 3.7A)
 0.62A 1jr1A-4af0B:
57.1		 1jr1A-4af0B:
56.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		6 / 11 SER B 290
ASN B 317
MET B 339
GLY B 340
GLY B 471
GLN B 470
 MOA  B1526 (-2.6A)
MOA  B1526 ( 3.6A)
None
MOA  B1526 (-4.0A)
IMP  B1527 (-3.1A)
MOA  B1526 ( 3.7A)
 1.17A 1jr1A-4af0B:
57.1		 1jr1A-4af0B:
56.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 11 SER B 290
SER B 289
GLY B 265
THR B 266
GLN B 297
 MOA  B1526 (-2.6A)
MOA  B1526 (-3.9A)
None
None
None
 1.33A 1jr1A-4af0B:
57.1		 1jr1A-4af0B:
56.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 8 ASP B 288
ASN B 317
ARG B 336
GLY B 340
GLY B 427
 MOA  B1526 (-3.3A)
MOA  B1526 ( 3.6A)
MOA  B1526 (-3.6A)
MOA  B1526 (-4.0A)
IMP  B1527 (-3.2A)
 1.06A 1jr1B-4af0B:
57.3		 1jr1B-4af0B:
56.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 8 ASP B 288
ASN B 317
ARG B 336
GLY B 342
GLY B 429
 MOA  B1526 (-3.3A)
MOA  B1526 ( 3.6A)
MOA  B1526 (-3.6A)
IMP  B1527 (-3.3A)
IMP  B1527 ( 3.3A)
 1.10A 1jr1B-4af0B:
57.3		 1jr1B-4af0B:
56.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		7 / 8 ASP B 288
SER B 290
ASN B 317
ARG B 336
GLY B 340
GLY B 429
GLN B 470
 MOA  B1526 (-3.3A)
MOA  B1526 (-2.6A)
MOA  B1526 ( 3.6A)
MOA  B1526 (-3.6A)
MOA  B1526 (-4.0A)
IMP  B1527 ( 3.3A)
MOA  B1526 ( 3.7A)
 0.27A 1jr1B-4af0B:
57.3		 1jr1B-4af0B:
56.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		7 / 8 ASP B 288
SER B 289
SER B 290
ASN B 317
GLY B 340
CYH B 345
GLY B 429
 MOA  B1526 (-3.3A)
MOA  B1526 (-3.9A)
MOA  B1526 (-2.6A)
MOA  B1526 ( 3.6A)
MOA  B1526 (-4.0A)
IMP  B1527 (-3.3A)
IMP  B1527 ( 3.3A)
 0.46A 1me7A-4af0B:
47.8		 1me7A-4af0B:
33.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		6 / 10 ASP B 288
SER B 289
SER B 290
ASN B 317
GLY B 340
GLY B 429
 MOA  B1526 (-3.3A)
MOA  B1526 (-3.9A)
MOA  B1526 (-2.6A)
MOA  B1526 ( 3.6A)
MOA  B1526 (-4.0A)
IMP  B1527 ( 3.3A)
 0.32A 1mehA-4af0B:
47.2		 1mehA-4af0B:
33.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 8 ASP B 288
SER B 289
SER B 290
ASN B 317
GLY B 429
 MOA  B1526 (-3.3A)
MOA  B1526 (-3.9A)
MOA  B1526 (-2.6A)
MOA  B1526 ( 3.6A)
IMP  B1527 ( 3.3A)
 0.32A 1meiA-4af0B:
48.1		 1meiA-4af0B:
33.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		3 / 3 MET B 351
ASN B 317
GLN B 323
 MOA  B1526 ( 4.7A)
MOA  B1526 ( 3.6A)
None
 1.01A 1xoqB-4af0B:
undetectable		 1xoqB-4af0B:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		4 / 6 GLY B 105
SER B 250
LEU B  84
ILE B  77
 None
 0.86A 1yajF-4af0B:
undetectable		 1yajF-4af0B:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 12 TYR B 425
VAL B  91
SER B  86
GLY B 342
ILE B 344
 IMP  B1527 (-4.6A)
None
IMP  B1527 (-2.6A)
IMP  B1527 (-3.3A)
None
 1.41A 2dcfA-4af0B:
undetectable		 2dcfA-4af0B:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 11 GLY B 379
SER B 343
ASN B  51
GLY B 382
HIS B 386
 IMP  B1527 (-3.5A)
IMP  B1527 (-2.6A)
None
None
None
 1.28A 2hmaA-4af0B:
undetectable		 2hmaA-4af0B:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 11 ALA B 433
MET B  88
GLY B 471
ILE B 344
VAL B 476
 None
IMP  B1527 (-4.0A)
IMP  B1527 (-3.1A)
None
None
 1.15A 2uxpB-4af0B:
undetectable		 2uxpB-4af0B:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		4 / 7 GLY B 105
ILE B  77
THR B  74
LEU B  84
 None
 1.02A 2xrhA-4af0B:
undetectable		 2xrhA-4af0B:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 12 TYR B 425
VAL B  91
SER B  86
GLY B 342
ILE B 344
 IMP  B1527 (-4.6A)
None
IMP  B1527 (-2.6A)
IMP  B1527 (-3.3A)
None
 1.44A 3a65A-4af0B:
undetectable		 3a65A-4af0B:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 12 MET B  40
GLN B  37
ALA B 365
PHE B  53
LEU B 508
 None
 1.21A 3aodC-4af0B:
undetectable		 3aodC-4af0B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 12 MET B  40
GLN B  37
ALA B 392
GLY B 515
LEU B  56
 None
 1.37A 3aodC-4af0B:
undetectable		 3aodC-4af0B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		4 / 7 GLY B 292
ASP B 288
VAL B 286
ILE B 337
 None
MOA  B1526 (-3.3A)
None
None
 0.61A 3t3cA-4af0B:
undetectable		 3t3cA-4af0B:
10.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		7 / 8 ASP B 288
SER B 289
SER B 290
ASN B 317
CYH B 345
MET B 428
GLY B 429
 MOA  B1526 (-3.3A)
MOA  B1526 (-3.9A)
MOA  B1526 (-2.6A)
MOA  B1526 ( 3.6A)
IMP  B1527 (-3.3A)
None
IMP  B1527 ( 3.3A)
 0.86A 4fo4A-4af0B:
48.2		 4fo4A-4af0B:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		4 / 8 ASN B 317
GLY B 340
CYH B 345
GLY B 427
 MOA  B1526 ( 3.6A)
MOA  B1526 (-4.0A)
IMP  B1527 (-3.3A)
IMP  B1527 (-3.2A)
 0.82A 4fo4B-4af0B:
48.1		 4fo4B-4af0B:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		7 / 8 SER B 289
SER B 290
ASN B 317
GLY B 340
CYH B 345
MET B 428
GLY B 429
 MOA  B1526 (-3.9A)
MOA  B1526 (-2.6A)
MOA  B1526 ( 3.6A)
MOA  B1526 (-4.0A)
IMP  B1527 (-3.3A)
None
IMP  B1527 ( 3.3A)
 0.37A 4fo4B-4af0B:
48.1		 4fo4B-4af0B:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FXS_A_MOAA702_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 9 ASP B 288
SER B 289
SER B 290
GLY B 340
CYH B 345
 MOA  B1526 (-3.3A)
MOA  B1526 (-3.9A)
MOA  B1526 (-2.6A)
MOA  B1526 (-4.0A)
IMP  B1527 (-3.3A)
 0.85A 4fxsA-4af0B:
51.3		 4fxsA-4af0B:
37.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FXS_A_MOAA702_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		6 / 9 SER B 289
SER B 290
ASN B 317
GLY B 340
CYH B 345
ASP B 378
 MOA  B1526 (-3.9A)
MOA  B1526 (-2.6A)
MOA  B1526 ( 3.6A)
MOA  B1526 (-4.0A)
IMP  B1527 (-3.3A)
IMP  B1527 (-2.5A)
 0.47A 4fxsA-4af0B:
51.3		 4fxsA-4af0B:
37.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 10 ALA B 457
THR B 456
ALA B 455
VAL B 472
ASP B 452
 None
 1.02A 4qvyK-4af0B:
undetectable
4qvyL-4af0B:
undetectable		 4qvyK-4af0B:
18.73
4qvyL-4af0B:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 10 ALA B 457
THR B 456
ALA B 455
VAL B 472
ASP B 452
 None
 1.02A 4qvyY-4af0B:
undetectable
4qvyZ-4af0B:
undetectable		 4qvyY-4af0B:
18.73
4qvyZ-4af0B:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 12 ALA B  73
ALA B 262
ILE B 108
ILE B 304
GLY B 334
 None
 0.92A 4r3aB-4af0B:
undetectable		 4r3aB-4af0B:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 12 LEU B  84
ILE B 376
GLY B 379
ILE B 337
ALA B 360
 None
None
IMP  B1527 (-3.5A)
None
None
 1.34A 5j7wC-4af0B:
undetectable		 5j7wC-4af0B:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 12 ASP B  89
ASP B 270
HIS B 111
SER B  86
GLY B 429
 None
None
None
IMP  B1527 (-2.6A)
IMP  B1527 ( 3.3A)
 1.15A 6b0lB-4af0B:
undetectable		 6b0lB-4af0B:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 12 LEU B 287
VAL B 364
ARG B 336
ILE B 337
ASP B 378
 None
None
MOA  B1526 (-3.6A)
None
IMP  B1527 (-2.5A)
 1.41A 6bxnA-4af0B:
undetectable		 6bxnA-4af0B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Cryptococcus
neoformans) 		5 / 12 LEU B  84
ILE B 376
GLY B 379
ILE B 337
ALA B 360
 None
None
IMP  B1527 (-3.5A)
None
None
 1.34A 6qyaD-4af0B:
undetectable		 6qyaD-4af0B:
21.42