SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4agv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 4agv GALECTIN
(Cinachyrella) 		4 / 7 ASN A  60
TRP A  68
ARG A  47
ARG A  28
 None
 1.39A 1f9gA-4agvA:
undetectable		 1f9gA-4agvA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 4agv GALECTIN
(Cinachyrella) 		3 / 3 PHE A  48
TYR A  21
PRO A  24
 None
 1.11A 1mcnA-4agvA:
undetectable
1mcnB-4agvA:
undetectable
1mcnP-4agvA:
undetectable		 1mcnA-4agvA:
22.79
1mcnB-4agvA:
22.79
1mcnP-4agvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 4agv GALECTIN
(Cinachyrella) 		4 / 6 ARG A  47
ASN A  60
TRP A  68
GLU A  71
 None
 0.45A 3galA-4agvA:
18.6		 3galA-4agvA:
28.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 4agv GALECTIN
(Cinachyrella) 		4 / 6 ARG A  47
ASN A  60
TRP A  68
GLU A  71
 None
 0.50A 3galB-4agvA:
18.2		 3galB-4agvA:
28.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 4agv GALECTIN
(Cinachyrella) 		4 / 7 PHE A  77
VAL A  90
ILE A  88
SER A  30
 None
 0.95A 3pglA-4agvA:
undetectable		 3pglA-4agvA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_C_NCAC302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4agv GALECTIN
(Cinachyrella) 		5 / 10 TYR A 126
LEU A  31
ASP A  45
ALA A  46
TYR A  21
 None
 1.45A 3rodC-4agvA:
undetectable		 3rodC-4agvA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 4agv GALECTIN
(Cinachyrella) 		3 / 3 ARG A  51
ARG A  47
TRP A  50
 None
 1.43A 4b7nA-4agvA:
undetectable		 4b7nA-4agvA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 4agv GALECTIN
(Cinachyrella) 		3 / 3 ARG A  51
ARG A  47
TRP A  50
 None
 1.42A 4cpzC-4agvA:
undetectable		 4cpzC-4agvA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 4agv GALECTIN
(Cinachyrella) 		3 / 3 ARG A  51
ARG A  47
TRP A  50
 None
 1.40A 4cpzE-4agvA:
undetectable		 4cpzE-4agvA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 4agv GALECTIN
(Cinachyrella) 		3 / 3 ARG A  51
ARG A  47
TRP A  50
 None
 1.40A 4cpzF-4agvA:
undetectable		 4cpzF-4agvA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 4agv GALECTIN
(Cinachyrella) 		3 / 3 ARG A  51
ARG A  47
TRP A  50
 None
 1.37A 4cpzG-4agvA:
undetectable		 4cpzG-4agvA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 4agv GALECTIN
(Cinachyrella) 		3 / 3 ARG A  51
ARG A  47
TRP A  50
 None
 1.42A 4cpzH-4agvA:
undetectable		 4cpzH-4agvA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4agv GALECTIN
(Cinachyrella) 		3 / 3 TYR A  32
ARG A  28
SER A  30
 None
 1.10A 4khpI-4agvA:
undetectable
4khpJ-4agvA:
undetectable		 4khpI-4agvA:
22.88
4khpJ-4agvA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4agv GALECTIN
(Cinachyrella) 		5 / 7 LEU A  59
ARG A 114
LEU A  42
GLU A 107
LEU A 101
 None
 1.31A 4wg0L-4agvA:
undetectable
4wg0M-4agvA:
undetectable		 4wg0L-4agvA:
5.48
4wg0M-4agvA:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 4agv GALECTIN
(Cinachyrella) 		5 / 7 ARG A  47
ASN A  60
TRP A  68
GLU A  71
ARG A  73
 None
 0.38A 6b8kA-4agvA:
17.9		 6b8kA-4agvA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 4agv GALECTIN
(Cinachyrella) 		5 / 8 ARG A  47
ASN A  60
TRP A  68
GLU A  71
ARG A  73
 None
 0.60A 6b94A-4agvA:
16.9		 6b94A-4agvA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 4agv GALECTIN
(Cinachyrella) 		5 / 10 ARG A  47
ASN A  60
TRP A  68
GLU A  71
ARG A  73
 None
 0.51A 6b94A-4agvA:
16.9
6b94B-4agvA:
16.2		 6b94A-4agvA:
23.44
6b94B-4agvA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 4agv GALECTIN
(Cinachyrella) 		4 / 4 ARG A  47
GLU A  53
GLU A  71
ARG A  73
 None
 0.32A 6fk2A-4agvA:
17.9		 6fk2A-4agvA:
29.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 4agv GALECTIN
(Cinachyrella) 		4 / 4 ARG A  73
GLU A  71
GLU A  53
ARG A  47
 None
 1.07A 6fk2A-4agvA:
17.9		 6fk2A-4agvA:
29.14