SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4aij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 6 TRP A  16
ARG A  17
ILE A  20
TRP A  34
 None
 0.63A 3deuA-4aijA:
18.1		 3deuA-4aijA:
63.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 6 TRP A  16
ILE A  20
TRP A  34
VAL A  35
 None
 0.52A 3deuA-4aijA:
18.1		 3deuA-4aijA:
63.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		5 / 7 THR A  32
VAL A  35
THR A  36
ILE A  56
THR A  66
 None
 0.80A 3deuA-4aijA:
18.1		 3deuA-4aijA:
63.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		5 / 7 VAL A  35
THR A  36
ILE A  56
ILE A  58
SER A  62
 None
 0.96A 3deuA-4aijA:
18.1		 3deuA-4aijA:
63.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		5 / 7 VAL A  35
THR A  36
ILE A  56
ILE A  58
THR A  66
 None
 0.97A 3deuA-4aijA:
18.1		 3deuA-4aijA:
63.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 6 THR A  32
THR A  36
LEU A  63
THR A  66
 None
 0.46A 3deuB-4aijA:
17.9		 3deuB-4aijA:
63.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 6 THR A  36
ILE A  58
LEU A  63
THR A  66
 None
 0.65A 3deuB-4aijA:
17.9		 3deuB-4aijA:
63.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		3 / 3 GLN A  31
THR A  30
LEU A  63
 None
 0.64A 3ondA-4aijA:
undetectable		 3ondA-4aijA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		3 / 3 GLN A  31
THR A  30
LEU A  63
 None
 0.65A 3ondB-4aijA:
undetectable		 3ondB-4aijA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  98
VAL A 103
LEU A  27
LEU A  29
 None
 0.90A 3u5kA-4aijA:
undetectable		 3u5kA-4aijA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 7 PRO A  98
VAL A 103
LEU A  27
LEU A  29
 None
 0.91A 3u5kB-4aijA:
undetectable		 3u5kB-4aijA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  98
VAL A 103
LEU A  27
LEU A  29
 None
 0.92A 3u5kC-4aijA:
undetectable		 3u5kC-4aijA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  98
VAL A 103
LEU A  27
LEU A  29
 None
 0.89A 3u5kD-4aijA:
undetectable		 3u5kD-4aijA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 5 GLN A  60
THR A  32
HIS A  33
LEU A  70
 None
 1.28A 4lvcA-4aijA:
undetectable		 4lvcA-4aijA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 5 GLN A  60
THR A  32
HIS A  33
LEU A  70
 None
 1.29A 4lvcC-4aijA:
undetectable		 4lvcC-4aijA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  98
VAL A 103
LEU A  27
LEU A  29
 None
 0.93A 5y1yA-4aijA:
undetectable		 5y1yA-4aijA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 5 GLN A  60
THR A  32
HIS A  33
LEU A  67
 None
 1.34A 6aphA-4aijA:
undetectable		 6aphA-4aijA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 5 GLN A  60
THR A  32
HIS A  33
LEU A  70
 None
 1.27A 6gbnA-4aijA:
undetectable		 6gbnA-4aijA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 5 GLN A  60
THR A  32
HIS A  33
LEU A  67
 None
 1.34A 6gbnB-4aijA:
undetectable		 6gbnB-4aijA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 4aij TRANSCRIPTIONAL
REGULATOR SLYA
(Yersinia
pseudotuberculos
is) 		4 / 5 GLN A  60
THR A  32
HIS A  33
LEU A  70
 None
 1.27A 6gbnD-4aijA:
undetectable		 6gbnD-4aijA:
17.00