SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4aip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		3 / 3 GLU A 447
ILE A 449
ARG A  62
 None
 0.74A 1cd2A-4aipA:
undetectable		 1cd2A-4aipA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.87A 1hshA-4aipA:
undetectable		 1hshA-4aipA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 5 ASP A 127
SER A 128
ASN A 115
SER A 507
 None
 0.98A 1kiaB-4aipA:
undetectable		 1kiaB-4aipA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 6 ASP A 127
SER A 128
ASN A 115
SER A 507
 None
 1.00A 1kiaC-4aipA:
undetectable		 1kiaC-4aipA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 10 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.97A 1muiA-4aipA:
undetectable		 1muiA-4aipA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		3 / 3 ASP A 273
THR A 306
GLU A 283
 None
 0.83A 1pj7A-4aipA:
undetectable		 1pj7A-4aipA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 ARG A 465
ASP A 118
GLY A 161
SER A 505
ILE A 160
 None
 1.42A 1q8jA-4aipA:
undetectable		 1q8jA-4aipA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 GLY A 363
ASN A 329
ASN A 312
LEU A 143
VAL A 144
 None
 1.19A 1r30A-4aipA:
undetectable		 1r30A-4aipA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 GLY A 363
ASN A 329
ASN A 312
LEU A 143
VAL A 144
 None
 1.19A 1r30B-4aipA:
undetectable		 1r30B-4aipA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 6 ILE A 523
ALA A 578
THR A 529
ALA A 581
 None
 0.98A 1w0gA-4aipA:
undetectable		 1w0gA-4aipA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 10 VAL A 147
ILE A 119
ILE A  95
LEU A  89
PHE A  97
 None
 1.10A 1z11D-4aipA:
undetectable		 1z11D-4aipA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 10 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.92A 2aquA-4aipA:
undetectable		 2aquA-4aipA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 11 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.91A 2aquB-4aipA:
undetectable		 2aquB-4aipA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		3 / 3 LYS A 248
ASP A 225
ASN A 101
 None
 1.11A 2bm9A-4aipA:
undetectable		 2bm9A-4aipA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 11 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.89A 2fxeB-4aipA:
undetectable		 2fxeB-4aipA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 6 ARG A  86
GLY A  98
PRO A 728
THR A 726
 None
 1.02A 2m2oB-4aipA:
undetectable		 2m2oB-4aipA:
2.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.91A 2nmyA-4aipA:
undetectable		 2nmyA-4aipA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		3 / 3 ARG A  86
ASN A 625
THR A 726
 None
 0.76A 2q63A-4aipA:
undetectable		 2q63A-4aipA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 VAL A 680
ALA A 624
THR A 108
ALA A 630
ARG A 722
 None
 1.09A 2qm9A-4aipA:
3.8		 2qm9A-4aipA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 10 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.92A 2r5qD-4aipA:
undetectable		 2r5qD-4aipA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		3 / 3 ASN A 365
ASN A 383
ARG A 462
 None
 0.68A 2rlcA-4aipA:
undetectable		 2rlcA-4aipA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 8 SER A  94
VAL A 117
PHE A 555
ASN A 586
 None
 1.10A 2wekA-4aipA:
undetectable		 2wekA-4aipA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 8 SER A  94
VAL A 117
PHE A 555
ASN A 586
 None
 1.13A 2wekB-4aipA:
undetectable		 2wekB-4aipA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 10 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.88A 3ekyA-4aipA:
undetectable		 3ekyA-4aipA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 11 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.95A 3em4A-4aipA:
undetectable		 3em4A-4aipA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 11 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.91A 3em4U-4aipA:
undetectable		 3em4U-4aipA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		3 / 3 LYS A 695
PRO A 696
LEU A 697
 None
 0.82A 3tpxE-4aipA:
undetectable		 3tpxE-4aipA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 10 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.94A 3ttpA-4aipA:
undetectable		 3ttpA-4aipA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 10 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.97A 3ttpB-4aipA:
undetectable		 3ttpB-4aipA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 8 LEU A 640
VAL A 604
TYR A 595
LEU A 600
 None
 1.05A 3v81A-4aipA:
undetectable		 3v81A-4aipA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 11 ARG A 188
VAL A 144
SER A 250
ASP A 273
VAL A 139
 None
 1.02A 4d9hA-4aipA:
undetectable		 4d9hA-4aipA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 11 ARG A 188
VAL A 144
SER A 250
ASP A 273
VAL A 139
 None
 1.15A 4danA-4aipA:
undetectable		 4danA-4aipA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_A_ACTA1002_0
(ACTIN, ALPHA
SKELETAL MUSCLE
FORMIN-LIKE PROTEIN
3)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 5 ARG A 682
THR A 724
GLN A 670
GLU A 678
 None
 1.40A 4eahA-4aipA:
undetectable
4eahE-4aipA:
undetectable
4eahG-4aipA:
undetectable		 4eahA-4aipA:
19.79
4eahE-4aipA:
19.79
4eahG-4aipA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_E_ACTE1001_0
(ACTIN, ALPHA
SKELETAL MUSCLE
FORMIN-LIKE PROTEIN
3)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 4 THR A 724
GLN A 670
GLU A 678
ARG A 682
 None
 1.38A 4eahA-4aipA:
undetectable
4eahD-4aipA:
0.0
4eahE-4aipA:
undetectable		 4eahA-4aipA:
19.79
4eahD-4aipA:
18.70
4eahE-4aipA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF401_0
(ACTIN, ALPHA
SKELETAL MUSCLE
FORMIN-LIKE PROTEIN
3)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 4 ARG A 682
THR A 724
GLN A 670
GLU A 678
 None
 1.44A 4eahB-4aipA:
undetectable
4eahC-4aipA:
undetectable
4eahF-4aipA:
0.0		 4eahB-4aipA:
19.79
4eahC-4aipA:
19.79
4eahF-4aipA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		3 / 3 PRO A 728
TYR A 226
GLY A 229
 None
 0.65A 4g2zA-4aipA:
undetectable		 4g2zA-4aipA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 7 VAL A 730
SER A 244
TYR A 226
ASP A  84
 None
 1.24A 4hxyB-4aipA:
undetectable		 4hxyB-4aipA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 ALA A 448
SER A 155
GLY A 460
ASP A 451
THR A 456
 None
 1.35A 4mm4A-4aipA:
undetectable		 4mm4A-4aipA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 ALA A 162
GLY A 161
ASN A 482
ASN A 536
GLY A 152
 None
 1.08A 4obwD-4aipA:
undetectable		 4obwD-4aipA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 ALA A 593
GLY A 592
ASN A 542
ARG A 596
PHE A 548
 None
 1.19A 4obwD-4aipA:
undetectable		 4obwD-4aipA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 GLY A 460
GLY A 459
SER A 157
ALA A 156
ARG A 533
 None
 0.99A 4qtuD-4aipA:
undetectable		 4qtuD-4aipA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 10 GLY A 652
LEU A 600
ALA A 602
SER A 639
ALA A 638
 None
 1.33A 4wnuD-4aipA:
undetectable		 4wnuD-4aipA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_A_ACTA403_0
(3C-LIKE PROTEINASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 5 TYR A 331
SER A 126
LEU A 333
GLN A 387
 None
 1.37A 4yo9A-4aipA:
undetectable
4yo9B-4aipA:
undetectable		 4yo9A-4aipA:
18.83
4yo9B-4aipA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 7 ARG A 385
ARG A 462
ASP A 464
TYR A 125
 None
 0.91A 5a06A-4aipA:
undetectable		 5a06A-4aipA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 7 ARG A 385
ARG A 462
ASP A 464
TYR A 125
 None
 0.89A 5a06C-4aipA:
undetectable		 5a06C-4aipA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 7 ARG A 385
ARG A 462
ASP A 464
TYR A 125
 None
 0.91A 5a06D-4aipA:
undetectable		 5a06D-4aipA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 7 ARG A 385
ARG A 462
ASP A 464
TYR A 125
 None
 0.90A 5a06E-4aipA:
undetectable		 5a06E-4aipA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 7 ARG A 385
ARG A 462
ASP A 464
TYR A 125
 None
 0.91A 5a06F-4aipA:
undetectable		 5a06F-4aipA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		3 / 3 ARG A 304
THR A 345
ASP A 342
 None
 0.73A 5g5gA-4aipA:
undetectable
5g5gB-4aipA:
undetectable		 5g5gA-4aipA:
15.86
5g5gB-4aipA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 5 GLU A  92
GLY A 592
SER A  65
GLY A  64
 None
 1.14A 5kprA-4aipA:
undetectable		 5kprA-4aipA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 5 GLU A 447
GLY A 381
ARG A 462
GLY A 443
 None
 0.94A 5kprA-4aipA:
undetectable		 5kprA-4aipA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		5 / 12 GLY A 165
ALA A 166
ASP A 118
GLY A 159
ILE A 168
 None
 0.86A 5kqxA-4aipA:
undetectable		 5kqxA-4aipA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 6 TYR A 445
ASP A 369
VAL A 323
ALA A 158
 None
 1.00A 6djzB-4aipA:
undetectable		 6djzB-4aipA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		4 / 5 VAL A 687
LYS A 714
ASN A 710
PRO A 718
 None
 1.45A 6fi4A-4aipA:
undetectable
6fi4B-4aipA:
undetectable		 6fi4A-4aipA:
15.75
6fi4B-4aipA:
0.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4aip FE-REGULATED PROTEIN
B
(Neisseria
meningitidis) 		3 / 3 VAL A 579
ALA A 581
GLN A 567
 None
 0.66A 6gb9A-4aipA:
undetectable		 6gb9A-4aipA:
21.38