SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ak2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4ak2 BT_4661
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 612
VAL A 554
ARG A 558
 None
 0.97A 3b0wA-4ak2A:
undetectable		 3b0wA-4ak2A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4ak2 BT_4661
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 464
HIS A 534
LEU A 436
 None
 0.78A 5axdA-4ak2A:
undetectable		 5axdA-4ak2A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4ak2 BT_4661
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 694
GLY A 598
ASN A 606
ILE A 668
 None
None
None
NA  A1715 ( 4.7A)
 0.97A 5j4nB-4ak2A:
undetectable		 5j4nB-4ak2A:
18.68