SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4akd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		4 / 7 THR A   5
VAL A 131
VAL A   8
ILE A   6
 None
 0.92A 1p7rA-4akdA:
undetectable		 1p7rA-4akdA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		4 / 7 THR A 101
TYR A 113
TYR A  34
LEU A  32
 None
 1.07A 1qzrA-4akdA:
undetectable		 1qzrA-4akdA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		4 / 7 THR A 101
TYR A 113
TYR A  34
LEU A  32
 None
 1.07A 1qzrB-4akdA:
undetectable		 1qzrB-4akdA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		4 / 4 LEU A 100
SER A  99
TYR A  34
LEU A  32
 None
 1.31A 1xz1A-4akdA:
undetectable		 1xz1A-4akdA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		4 / 4 LEU A 100
SER A  99
TYR A  34
LEU A  32
 None
 1.32A 1xz3A-4akdA:
undetectable		 1xz3A-4akdA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		4 / 6 HIS A  57
PHE A  41
TYR A  24
LYS A 134
 None
 1.42A 2i30A-4akdA:
undetectable		 2i30A-4akdA:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		4 / 7 ASP A  21
PHE A 133
GLY A 145
PHE A  41
 None
 0.96A 3vnsA-4akdA:
undetectable		 3vnsA-4akdA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		4 / 8 PHE A 121
TYR A  83
VAL A  97
ILE A  38
 None
 1.07A 4a97G-4akdA:
undetectable		 4a97G-4akdA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		5 / 11 GLY A  16
GLY A  15
ASP A 142
LEU A 140
VAL A  96
 None
 1.13A 4pghA-4akdA:
undetectable		 4pghA-4akdA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		3 / 3 ASP A 139
GLY A 138
ASP A 142
 None
 0.70A 4xdtA-4akdA:
undetectable		 4xdtA-4akdA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 4akd MANNOSE-SPECIFIC
LECTIN KM+
(Artocarpus
integer) 		5 / 12 LEU A  77
PHE A 121
ALA A 149
THR A   5
GLY A   9
 None
 1.13A 5veuA-4akdA:
undetectable		 5veuA-4akdA:
16.88