SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4alb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KF6_N_ACTN803_0 (FUMARATE REDUCTASE FLAVOPROTEIN FUMARATE REDUCTASE IRON-SULFUR PROTEIN)	4alb	PHENOLIC ACID DECARBOXYLASE PADC (Bacillus subtilis)	4 / 6	ARG A 157 GLY A 151 ASP A 154 TYR A 149	None	1.46A	1kf6M-4albA: undetectable 1kf6N-4albA: undetectable	1kf6M-4albA: 14.55 1kf6N-4albA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2D55_C_DVAC2_0 (ACTINOMYCIN D)	4alb	PHENOLIC ACID DECARBOXYLASE PADC (Bacillus subtilis)	3 / 3	THR A 118 PRO A 120 PRO A 88	None	0.56A	2d55C-4albA: undetectable	2d55C-4albA: 11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESG_A_1YNA701_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4alb	PHENOLIC ACID DECARBOXYLASE PADC (Bacillus subtilis)	5 / 12	GLU A 78 ILE A 29 PHE A 4 GLY A 6 LEU A 133	None	1.39A	5esgA-4albA: undetectable	5esgA-4albA: 16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_A_CVIA301_0 (REGULATORY PROTEIN TETR)	4alb	PHENOLIC ACID DECARBOXYLASE PADC (Bacillus subtilis)	5 / 12	MET A 75 SER A 7 GLU A 136 LEU A 133 TYR A 13	None	1.18A	5vlmA-4albA: undetectable	5vlmA-4albA: 16.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KF6_N_ACTN803_0","FUMARATE REDUCTASE FLAVOPROTEIN;FUMARATE REDUCTASE IRON-SULFUR PROTEIN","4alb","PHENOLIC ACID DECARBOXYLASE PADC","Bacillus subtilis",4,"ARG A 157;GLY A 151;ASP A 154;TYR A 149","None","1.46A","1kf6M-4albA:undetectable;1kf6N-4albA:undetectable","1kf6M-4albA:14.55;1kf6N-4albA:21.26"],["2D55_C_DVAC2_0","ACTINOMYCIN D","4alb","PHENOLIC ACID DECARBOXYLASE PADC","Bacillus subtilis",3,"THR A 118;PRO A 120;PRO A  88","None","0.56A","2d55C-4albA:undetectable","2d55C-4albA:11.84"],["5ESG_A_1YNA701_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4alb","PHENOLIC ACID DECARBOXYLASE PADC","Bacillus subtilis",5,"GLU A  78;ILE A  29;PHE A   4;GLY A   6;LEU A 133","None","1.39A","5esgA-4albA:undetectable","5esgA-4albA:16.48"],["5VLM_A_CVIA301_0","REGULATORY PROTEIN TETR","4alb","PHENOLIC ACID DECARBOXYLASE PADC","Bacillus subtilis",5,"MET A  75;SER A   7;GLU A 136;LEU A 133;TYR A  13","None","1.18A","5vlmA-4albA:undetectable","5vlmA-4albA:16.22"]]