SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4alq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA8_0
(GRAMICIDIN A)		 4alq CHITIN BINDING
PROTEIN
(Enterococcus
faecalis) 		4 / 4 GLY A  30
VAL A  32
TRP A 176
TRP A 119
 None
 1.44A 1magA-4alqA:
undetectable		 1magA-4alqA:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB8_0
(GRAMICIDIN A)		 4alq CHITIN BINDING
PROTEIN
(Enterococcus
faecalis) 		4 / 4 GLY A  30
VAL A  32
TRP A 176
TRP A 119
 None
 1.44A 1magB-4alqA:
undetectable		 1magB-4alqA:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4alq CHITIN BINDING
PROTEIN
(Enterococcus
faecalis) 		4 / 5 ASP A 180
GLY A 177
PRO A 152
VAL A 151
 None
 0.87A 2aoiA-4alqA:
undetectable		 2aoiA-4alqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4alq CHITIN BINDING
PROTEIN
(Enterococcus
faecalis) 		4 / 5 ASP A 180
GLY A 177
PRO A 152
VAL A 151
 None
 0.82A 2aojA-4alqA:
undetectable		 2aojA-4alqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4alq CHITIN BINDING
PROTEIN
(Enterococcus
faecalis) 		4 / 7 LYS A 141
SER A 118
VAL A 175
SER A 144
 None
 1.30A 2j9cA-4alqA:
undetectable
2j9cB-4alqA:
undetectable
2j9cC-4alqA:
undetectable		 2j9cA-4alqA:
20.75
2j9cB-4alqA:
20.75
2j9cC-4alqA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4alq CHITIN BINDING
PROTEIN
(Enterococcus
faecalis) 		5 / 12 HIS A 170
PRO A 130
PHE A 139
THR A  72
GLY A  73
 None
 1.40A 4hvcA-4alqA:
undetectable		 4hvcA-4alqA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4alq CHITIN BINDING
PROTEIN
(Enterococcus
faecalis) 		4 / 6 ILE A 160
VAL A  32
THR A  97
ARG A 166
 None
 1.19A 4xe5A-4alqA:
undetectable		 4xe5A-4alqA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 4alq CHITIN BINDING
PROTEIN
(Enterococcus
faecalis) 		3 / 3 PHE A 139
ASP A 140
LYS A 125
 None
 0.84A 6awtD-4alqA:
undetectable		 6awtD-4alqA:
19.64