SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4am9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  36
LEU A  39
LEU A  42
GLN A  46
CYH A  63
 None
 0.77A 1a28B-4am9A:
undetectable		 1a28B-4am9A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  36
LEU A  39
LEU A  42
GLN A  46
CYH A  63
 None
 0.71A 1sqnA-4am9A:
undetectable		 1sqnA-4am9A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  36
LEU A  39
LEU A  42
GLN A  46
CYH A  63
 None
 0.72A 1sqnB-4am9A:
undetectable		 1sqnB-4am9A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  36
LEU A  42
ALA A  43
GLN A  46
CYH A  63
 None
 0.84A 1ya3A-4am9A:
undetectable		 1ya3A-4am9A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		6 / 12 LEU A  36
LEU A  39
LEU A  42
ALA A  43
GLN A  46
CYH A  63
 None
 0.82A 1ya3C-4am9A:
undetectable		 1ya3C-4am9A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  36
LEU A  42
ALA A  43
GLN A  46
CYH A  63
 None
 0.81A 2aa5B-4am9A:
undetectable		 2aa5B-4am9A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  39
LEU A  42
ALA A  43
GLN A  46
CYH A  63
 None
 0.73A 2aa6A-4am9A:
undetectable		 2aa6A-4am9A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  36
LEU A  42
ALA A  43
GLN A  46
CYH A  63
 None
 0.85A 2oaxB-4am9A:
undetectable		 2oaxB-4am9A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  36
LEU A  39
LEU A  42
GLN A  46
CYH A  63
 None
 0.71A 2w8yB-4am9A:
undetectable		 2w8yB-4am9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  36
LEU A  39
LEU A  42
GLN A  46
CYH A  63
 None
 0.64A 3d90A-4am9A:
undetectable		 3d90A-4am9A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  36
LEU A  39
LEU A  42
GLN A  46
CYH A  63
 None
 0.67A 3d90B-4am9A:
undetectable		 3d90B-4am9A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		6 / 12 LEU A  36
LEU A  39
LEU A  42
ALA A  43
GLN A  46
CYH A  63
 None
 0.84A 4fn9A-4am9A:
undetectable		 4fn9A-4am9A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		5 / 12 LEU A  36
LEU A  39
LEU A  42
ALA A  43
GLN A  46
 None
 0.65A 4fn9B-4am9A:
undetectable		 4fn9B-4am9A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		6 / 12 LEU A  36
LEU A  39
LEU A  42
ALA A  43
GLN A  46
CYH A  63
 None
 0.79A 4ltwA-4am9A:
undetectable		 4ltwA-4am9A:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 4am9 CHAPERONE SYCD
(Yersinia
enterocolitica) 		4 / 6 ARG A 105
ALA A 130
PRO A 104
PHE A 140
 None
 1.18A 5odqA-4am9A:
undetectable		 5odqA-4am9A:
11.90