SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4amm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 4amm DYNE8
(Micromonospora
chersina) 		4 / 8 PRO A 644
LEU A 860
GLY A 856
LEU A 637
 None
 0.89A 1ya4A-4ammA:
undetectable		 1ya4A-4ammA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 4amm DYNE8
(Micromonospora
chersina) 		4 / 7 PRO A 644
LEU A 860
GLY A 856
LEU A 637
 None
 0.91A 1ya4B-4ammA:
undetectable		 1ya4B-4ammA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 11 VAL A 841
THR A 839
ALA A 863
ALA A 530
ASP A 867
 None
 1.25A 2admB-4ammA:
undetectable		 2admB-4ammA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 9 LEU A 491
LEU A 566
HIS A 549
ARG A 556
ALA A 863
 None
 1.20A 2bxcB-4ammA:
undetectable		 2bxcB-4ammA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 4amm DYNE8
(Micromonospora
chersina) 		4 / 4 ALA A 518
VAL A 481
PHE A 872
THR A 511
 None
 1.44A 2pkkA-4ammA:
undetectable		 2pkkA-4ammA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4amm DYNE8
(Micromonospora
chersina) 		4 / 6 LEU A 576
ALA A 817
LEU A 819
ALA A 863
 None
 0.99A 2vcvK-4ammA:
undetectable		 2vcvK-4ammA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4amm DYNE8
(Micromonospora
chersina) 		4 / 8 LEU A 480
LEU A 539
ALA A 542
PHE A 529
 None
 0.63A 2vcvP-4ammA:
undetectable		 2vcvP-4ammA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 12 GLY A 856
GLY A 633
GLY A 824
GLU A 822
ILE A 634
 None
 1.20A 2wa2A-4ammA:
undetectable		 2wa2A-4ammA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 4amm DYNE8
(Micromonospora
chersina) 		4 / 8 ARG A 676
GLY A 804
GLY A 580
MET A 690
 None
 0.94A 2y6rB-4ammA:
undetectable		 2y6rB-4ammA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 9 VAL A 823
GLY A 649
GLY A 653
ILE A 634
ALA A 647
 None
 0.99A 2z0yA-4ammA:
undetectable		 2z0yA-4ammA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 11 ALA A 760
LEU A 764
PHE A 752
GLY A 677
SER A 681
 None
 1.42A 3bpxA-4ammA:
undetectable
3bpxB-4ammA:
undetectable		 3bpxA-4ammA:
18.48
3bpxB-4ammA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 11 GLY A 864
PHE A 861
ARG A 573
ALA A 817
ALA A 642
 None
 1.10A 3g88A-4ammA:
undetectable		 3g88A-4ammA:
26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 11 GLY A 864
PHE A 861
ARG A 573
ALA A 817
ALA A 642
 None
 1.06A 3g89B-4ammA:
undetectable		 3g89B-4ammA:
26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 12 GLY A 864
PHE A 861
ARG A 573
ALA A 817
ALA A 642
 None
 1.08A 3g8bA-4ammA:
undetectable		 3g8bA-4ammA:
26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 12 GLY A 716
VAL A 721
GLY A 837
ALA A 835
ALA A 831
 None
 1.00A 3sudD-4ammA:
undetectable		 3sudD-4ammA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 4amm DYNE8
(Micromonospora
chersina) 		4 / 7 PRO A 776
GLY A 662
ALA A 661
ALA A 656
 None
 0.86A 3ur0B-4ammA:
undetectable		 3ur0B-4ammA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_C_SVRC516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 9 GLY A 864
ALA A 863
ALA A 817
ASP A 818
LEU A 558
 None
 1.25A 3ur0C-4ammA:
undetectable		 3ur0C-4ammA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 4amm DYNE8
(Micromonospora
chersina) 		4 / 8 ARG A 676
GLY A 804
GLY A 580
MET A 690
 None
 0.92A 3v3nB-4ammA:
undetectable		 3v3nB-4ammA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 4amm DYNE8
(Micromonospora
chersina) 		4 / 8 ARG A 676
GLY A 804
GLY A 580
MET A 690
 None
 0.92A 3v3nC-4ammA:
undetectable		 3v3nC-4ammA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 4amm DYNE8
(Micromonospora
chersina) 		6 / 12 ARG A 635
LEU A 843
GLY A 633
ALA A 632
SER A 630
LEU A 631
 None
 1.38A 4coxD-4ammA:
undetectable		 4coxD-4ammA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 11 LEU A 566
VAL A 481
CYH A 483
LEU A 543
ALA A 546
 None
 1.11A 4p65B-4ammA:
undetectable
4p65D-4ammA:
undetectable
4p65G-4ammA:
undetectable
4p65H-4ammA:
undetectable		 4p65B-4ammA:
7.05
4p65D-4ammA:
7.05
4p65G-4ammA:
5.70
4p65H-4ammA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 11 VAL A 823
LEU A 843
LEU A 819
LEU A 860
ALA A 859
 None
 1.09A 4p65B-4ammA:
undetectable
4p65D-4ammA:
undetectable
4p65G-4ammA:
undetectable
4p65H-4ammA:
undetectable		 4p65B-4ammA:
7.05
4p65D-4ammA:
7.05
4p65G-4ammA:
5.70
4p65H-4ammA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 12 VAL A 841
GLU A 834
LEU A 564
LEU A 557
ARG A 838
 None
 1.26A 5hnxB-4ammA:
undetectable		 5hnxB-4ammA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 12 PHE A 873
LEU A 510
LEU A 513
ALA A 531
LEU A 543
 None
 1.18A 5iepA-4ammA:
undetectable		 5iepA-4ammA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 12 PHE A 873
LEU A 510
ALA A 514
LEU A 517
LEU A 640
 None
 1.05A 5ljcA-4ammA:
undetectable		 5ljcA-4ammA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 4amm DYNE8
(Micromonospora
chersina) 		5 / 12 ALA A 656
SER A 659
PHE A 578
ARG A 635
LEU A 637
 None
 1.44A 5m54B-4ammA:
undetectable		 5m54B-4ammA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 4amm DYNE8
(Micromonospora
chersina) 		4 / 7 PHE A 529
LEU A 543
GLY A 538
GLY A 561
 None
 0.80A 6eu9D-4ammA:
undetectable		 6eu9D-4ammA:
11.14