SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4anf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 4anf ORNITHINE
CARBAMOYLTRANSFERASE
, CATABOLIC
(Mycoplasma
penetrans) 		4 / 5 LEU A  10
GLY A 131
ILE A 332
ILE A 335
 None
 0.64A 2q9rA-4anfA:
undetectable		 2q9rA-4anfA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 4anf ORNITHINE
CARBAMOYLTRANSFERASE
, CATABOLIC
(Mycoplasma
penetrans) 		3 / 3 ARG A 250
VAL A 259
THR A 234
 None
 0.86A 3k4vA-4anfA:
undetectable		 3k4vA-4anfA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 4anf ORNITHINE
CARBAMOYLTRANSFERASE
, CATABOLIC
(Mycoplasma
penetrans) 		4 / 8 ALA A 226
PHE A 162
THR A 174
PHE A 145
 None
 1.04A 4ltwA-4anfA:
undetectable		 4ltwA-4anfA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4anf ORNITHINE
CARBAMOYLTRANSFERASE
, CATABOLIC
(Mycoplasma
penetrans) 		4 / 5 ALA A 321
ARG A  61
HIS A 281
ALA A 279
 None
 1.25A 5a06C-4anfA:
4.5
5a06D-4anfA:
4.6		 5a06C-4anfA:
20.43
5a06D-4anfA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 4anf ORNITHINE
CARBAMOYLTRANSFERASE
, CATABOLIC
(Mycoplasma
penetrans) 		5 / 10 PHE A 180
ALA A 179
GLU A 136
GLY A 177
ILE A  25
 None
 1.19A 6bniB-4anfA:
undetectable		 6bniB-4anfA:
11.78