SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ang'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4ang COAT PROTEIN
(Pseudomonas
phage
PRR1) 		4 / 5 GLU A  42
GLY A  41
SER A  35
THR A  36
 None
 1.20A 1icrA-4angA:
undetectable
1icrB-4angA:
undetectable		 1icrA-4angA:
19.63
1icrB-4angA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4ang COAT PROTEIN
(Pseudomonas
phage
PRR1) 		4 / 5 SER A  35
THR A  36
GLU A  42
GLY A  41
 None
 1.24A 1icvC-4angA:
undetectable
1icvD-4angA:
undetectable		 1icvC-4angA:
19.63
1icvD-4angA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4ang COAT PROTEIN
(Pseudomonas
phage
PRR1) 		4 / 5 GLU A  42
GLY A  41
SER A  35
THR A  36
 None
 1.22A 1icvC-4angA:
undetectable
1icvD-4angA:
undetectable		 1icvC-4angA:
19.63
1icvD-4angA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4ang COAT PROTEIN
(Pseudomonas
phage
PRR1) 		4 / 5 GLU A  42
GLY A  41
SER A  35
THR A  36
 None
 1.21A 1kqbA-4angA:
undetectable
1kqbB-4angA:
undetectable		 1kqbA-4angA:
20.55
1kqbB-4angA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4ang COAT PROTEIN
(Pseudomonas
phage
PRR1) 		5 / 12 PHE A  91
ILE A  47
VAL A  89
PHE A  45
LEU A   8
 None
 1.21A 2ft9A-4angA:
3.6		 2ft9A-4angA:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 4ang COAT PROTEIN
(Pseudomonas
phage
PRR1) 		4 / 5 VAL A 106
VAL A  89
ASP A  90
SER A  59
 None
 1.33A 2x45C-4angA:
undetectable		 2x45C-4angA:
22.30