SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4anj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 8 MET A 320
PRO A 187
GLU A 190
ASP A 313
 None
 1.22A 1dtlA-4anjA:
undetectable		 1dtlA-4anjA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 6 SER A 642
VAL A 643
GLY A 644
GLU A 231
 None
 0.89A 1fduD-4anjA:
undetectable		 1fduD-4anjA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 11 ALA A1110
ILE A1014
LEU A1042
TYR A1092
THR A1108
 None
 1.28A 1jomA-4anjA:
undetectable		 1jomA-4anjA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 VAL A 756
LEU A 714
MET A 717
TYR A 718
ASP A 767
 None
 1.41A 1p5zB-4anjA:
undetectable		 1p5zB-4anjA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 8 ILE A1098
ASP A1129
GLY A1104
PHE A1100
 None
 0.86A 1rtsA-4anjA:
undetectable		 1rtsA-4anjA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 7 ILE A1098
ASP A1129
GLY A1104
PHE A1100
 None
 0.88A 1rtsB-4anjA:
undetectable		 1rtsB-4anjA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 6 HIS A 548
PHE A 468
LEU A 529
ILE A 525
 None
 1.23A 1sbrA-4anjA:
undetectable
1sbrB-4anjA:
undetectable		 1sbrA-4anjA:
11.14
1sbrB-4anjA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_B_MTXB170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 10 ALA A1110
ILE A1014
LEU A1042
TYR A1092
THR A1108
 None
 1.33A 1tdrB-4anjA:
undetectable		 1tdrB-4anjA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 8 TYR A  81
THR A 676
TYR A 100
LEU A 673
 None
None
ADP  A2230 (-4.5A)
None
 1.00A 1uw6A-4anjA:
undetectable
1uw6B-4anjA:
undetectable		 1uw6A-4anjA:
12.04
1uw6B-4anjA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 8 TYR A  81
THR A 676
TYR A 100
LEU A 673
 None
None
ADP  A2230 (-4.5A)
None
 1.03A 1uw6D-4anjA:
undetectable
1uw6E-4anjA:
undetectable		 1uw6D-4anjA:
12.04
1uw6E-4anjA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 8 TYR A  81
THR A 676
TYR A 100
LEU A 673
 None
None
ADP  A2230 (-4.5A)
None
 1.02A 1uw6G-4anjA:
undetectable
1uw6H-4anjA:
undetectable		 1uw6G-4anjA:
12.04
1uw6H-4anjA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 8 TYR A  81
THR A 676
TYR A 100
LEU A 673
 None
None
ADP  A2230 (-4.5A)
None
 1.02A 1uw6P-4anjA:
undetectable
1uw6Q-4anjA:
undetectable		 1uw6P-4anjA:
12.04
1uw6Q-4anjA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 8 LEU A 673
TYR A  81
THR A 676
TYR A 100
 None
None
None
ADP  A2230 (-4.5A)
 1.02A 1uw6P-4anjA:
undetectable
1uw6T-4anjA:
undetectable		 1uw6P-4anjA:
12.04
1uw6T-4anjA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 7 GLU A  60
PRO A 760
LYS A 762
GLY A 121
 None
 1.22A 2hs1B-4anjA:
undetectable		 2hs1B-4anjA:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		3 / 3 ASN A1170
LEU A1141
HIS A1169
 None
 0.87A 2q6fB-4anjA:
undetectable		 2q6fB-4anjA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 LEU A1044
LEU A1042
ILE A1014
ALA A1037
PHE A1071
 None
 1.15A 2qb4A-4anjA:
3.2		 2qb4A-4anjA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 7 ILE A 130
TYR A  89
PHE A 763
ASP A 767
 None
 1.16A 2qebA-4anjA:
undetectable		 2qebA-4anjA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 7 ILE A 130
TYR A  89
PHE A 763
ASP A 767
 None
 1.15A 2qebB-4anjA:
undetectable		 2qebB-4anjA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 8 ILE A 247
PHE A 432
TYR A 428
GLY A 193
 None
 0.93A 2vdbA-4anjA:
undetectable		 2vdbA-4anjA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 LEU A 378
ALA A 255
ALA A 342
VAL A 341
PHE A 192
 None
 1.18A 3b0wB-4anjA:
undetectable		 3b0wB-4anjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 GLY A  19
ASN A  20
GLY A  15
HIS A  11
LEU A  34
 None
 1.14A 3eeyA-4anjA:
undetectable		 3eeyA-4anjA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 GLY A  19
ASN A  20
GLY A  15
HIS A  11
LEU A  34
 None
 1.11A 3eeyB-4anjA:
undetectable		 3eeyB-4anjA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 GLY A  19
ASN A  20
GLY A  15
HIS A  11
LEU A  34
 None
 1.11A 3eeyC-4anjA:
undetectable		 3eeyC-4anjA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 GLY A  19
ASN A  20
GLY A  15
HIS A  11
LEU A  34
 None
 1.14A 3eeyD-4anjA:
undetectable		 3eeyD-4anjA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 LEU A 738
ILE A 769
PHE A 705
ASP A 748
PHE A 751
 None
 1.21A 3ko0A-4anjA:
undetectable
3ko0B-4anjA:
undetectable
3ko0C-4anjA:
undetectable
3ko0D-4anjA:
undetectable		 3ko0A-4anjA:
6.93
3ko0B-4anjA:
6.93
3ko0C-4anjA:
6.93
3ko0D-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 11 PHE A 751
LEU A 738
ILE A 769
PHE A 705
ASP A 748
 None
 1.30A 3ko0A-4anjA:
undetectable
3ko0B-4anjA:
undetectable
3ko0C-4anjA:
undetectable
3ko0D-4anjA:
undetectable		 3ko0A-4anjA:
6.93
3ko0B-4anjA:
6.93
3ko0C-4anjA:
6.93
3ko0D-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 11 ASP A 748
LEU A 738
ILE A 769
PHE A 705
PHE A 751
 None
 1.24A 3ko0C-4anjA:
undetectable
3ko0D-4anjA:
undetectable
3ko0E-4anjA:
undetectable
3ko0F-4anjA:
undetectable		 3ko0C-4anjA:
6.93
3ko0D-4anjA:
6.93
3ko0E-4anjA:
6.93
3ko0F-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 11 PHE A 751
LEU A 738
ILE A 769
PHE A 705
ASP A 748
 None
 1.22A 3ko0C-4anjA:
undetectable
3ko0D-4anjA:
undetectable
3ko0E-4anjA:
undetectable
3ko0F-4anjA:
undetectable		 3ko0C-4anjA:
6.93
3ko0D-4anjA:
6.93
3ko0E-4anjA:
6.93
3ko0F-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 11 ASP A 748
LEU A 738
ILE A 769
PHE A 705
PHE A 751
 None
 1.22A 3ko0E-4anjA:
undetectable
3ko0F-4anjA:
undetectable
3ko0G-4anjA:
undetectable
3ko0H-4anjA:
undetectable		 3ko0E-4anjA:
6.93
3ko0F-4anjA:
6.93
3ko0G-4anjA:
6.93
3ko0H-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 ASP A 748
LEU A 738
ILE A 769
PHE A 705
PHE A 751
 None
 1.28A 3ko0G-4anjA:
undetectable
3ko0H-4anjA:
undetectable
3ko0I-4anjA:
undetectable
3ko0J-4anjA:
undetectable		 3ko0G-4anjA:
6.93
3ko0H-4anjA:
6.93
3ko0I-4anjA:
6.93
3ko0J-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 PHE A 751
LEU A 738
ILE A 769
PHE A 705
ASP A 748
 None
 1.27A 3ko0G-4anjA:
undetectable
3ko0H-4anjA:
undetectable
3ko0I-4anjA:
undetectable
3ko0J-4anjA:
undetectable		 3ko0G-4anjA:
6.93
3ko0H-4anjA:
6.93
3ko0I-4anjA:
6.93
3ko0J-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 11 PHE A 751
ASP A 748
LEU A 738
ILE A 769
PHE A 705
 None
 1.22A 3ko0A-4anjA:
undetectable
3ko0B-4anjA:
undetectable
3ko0I-4anjA:
undetectable
3ko0J-4anjA:
undetectable		 3ko0A-4anjA:
6.93
3ko0B-4anjA:
6.93
3ko0I-4anjA:
6.93
3ko0J-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 ASP A 748
LEU A 738
ILE A 769
PHE A 705
PHE A 751
 None
 1.19A 3ko0K-4anjA:
undetectable
3ko0L-4anjA:
undetectable
3ko0M-4anjA:
undetectable
3ko0N-4anjA:
undetectable		 3ko0K-4anjA:
6.93
3ko0L-4anjA:
6.93
3ko0M-4anjA:
6.93
3ko0N-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 LEU A 738
ILE A 769
PHE A 705
ASP A 748
PHE A 751
 None
 1.22A 3ko0M-4anjA:
undetectable
3ko0N-4anjA:
undetectable
3ko0O-4anjA:
undetectable
3ko0P-4anjA:
undetectable		 3ko0M-4anjA:
6.93
3ko0N-4anjA:
6.93
3ko0O-4anjA:
6.93
3ko0P-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 11 PHE A 751
ASP A 748
LEU A 738
ILE A 769
PHE A 705
 None
 1.26A 3ko0K-4anjA:
undetectable
3ko0L-4anjA:
undetectable
3ko0M-4anjA:
undetectable
3ko0N-4anjA:
undetectable		 3ko0K-4anjA:
6.93
3ko0L-4anjA:
6.93
3ko0M-4anjA:
6.93
3ko0N-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 11 LEU A 738
ILE A 769
PHE A 705
ASP A 748
PHE A 751
 None
 1.24A 3ko0O-4anjA:
undetectable
3ko0P-4anjA:
undetectable
3ko0Q-4anjA:
undetectable
3ko0R-4anjA:
undetectable		 3ko0O-4anjA:
6.93
3ko0P-4anjA:
6.93
3ko0Q-4anjA:
6.93
3ko0R-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 PHE A 751
ASP A 748
LEU A 738
ILE A 769
PHE A 705
 None
 1.17A 3ko0M-4anjA:
undetectable
3ko0N-4anjA:
undetectable
3ko0O-4anjA:
undetectable
3ko0P-4anjA:
undetectable		 3ko0M-4anjA:
6.93
3ko0N-4anjA:
6.93
3ko0O-4anjA:
6.93
3ko0P-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 10 PHE A 751
LEU A 738
ILE A 769
PHE A 705
ASP A 748
 None
 1.24A 3ko0O-4anjA:
undetectable
3ko0P-4anjA:
undetectable
3ko0Q-4anjA:
undetectable
3ko0R-4anjA:
undetectable		 3ko0O-4anjA:
6.93
3ko0P-4anjA:
6.93
3ko0Q-4anjA:
6.93
3ko0R-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 11 PHE A 751
ASP A 748
LEU A 738
ILE A 769
PHE A 705
 None
 1.21A 3ko0Q-4anjA:
undetectable
3ko0R-4anjA:
undetectable
3ko0S-4anjA:
undetectable
3ko0T-4anjA:
undetectable		 3ko0Q-4anjA:
6.93
3ko0R-4anjA:
6.93
3ko0S-4anjA:
6.93
3ko0T-4anjA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 VAL A 341
TYR A 428
TYR A 245
ILE A 259
TYR A 249
 None
 1.45A 3q5pA-4anjA:
0.2		 3q5pA-4anjA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 ILE A 147
SER A 146
GLY A 453
SER A 144
THR A 661
 None
 1.23A 3r75A-4anjA:
undetectable		 3r75A-4anjA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 ILE A 147
SER A 146
GLY A 453
SER A 144
THR A 661
 None
 1.24A 3r75B-4anjA:
undetectable		 3r75B-4anjA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 7 LEU A 306
ASP A 313
ALA A 283
TYR A 300
 None
 1.18A 3rodD-4anjA:
undetectable		 3rodD-4anjA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		3 / 3 TYR A  81
LEU A  68
ARG A  80
 None
 0.71A 3sufB-4anjA:
undetectable		 3sufB-4anjA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 9 PHE A1071
VAL A1112
ASN A1121
ILE A1014
PHE A1008
 None
 1.18A 3t3rB-4anjA:
undetectable		 3t3rB-4anjA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 9 PHE A1071
VAL A1112
ASN A1121
ILE A1014
PHE A1008
 None
 1.22A 3t3rC-4anjA:
undetectable		 3t3rC-4anjA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 10 PHE A1071
VAL A1112
ASN A1121
ILE A1014
PHE A1008
 None
 1.15A 3t3rD-4anjA:
undetectable		 3t3rD-4anjA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 7 ALA A 283
TYR A 281
ARG A 250
ALA A 253
 None
 1.16A 3twpA-4anjA:
undetectable		 3twpA-4anjA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		3 / 3 GLY A 277
THR A 279
ASN A 275
 None
 0.66A 3v4tD-4anjA:
undetectable		 3v4tD-4anjA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		3 / 3 LYS A 162
ARG A 250
LEU A 310
 None
None
ADP  A2230 ( 4.3A)
 1.05A 3v4tE-4anjA:
undetectable		 3v4tE-4anjA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 6 GLU A 478
ILE A 515
PHE A 582
VAL A 697
 None
 1.20A 4a97I-4anjA:
2.4		 4a97I-4anjA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 4 ASN A  76
SER A 687
LEU A 686
THR A  88
 None
 1.31A 4an2A-4anjA:
1.4		 4an2A-4anjA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		3 / 3 ARG A 667
ASP A 510
GLN A 512
 None
 0.84A 4azsA-4anjA:
undetectable		 4azsA-4anjA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 ASN A  62
LEU A 689
ASN A  92
VAL A 697
LEU A  73
 None
 1.00A 4dc3A-4anjA:
undetectable		 4dc3A-4anjA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 4 ALA A  91
VAL A  90
ASP A  61
LEU A  68
 None
 1.03A 4e7gA-4anjA:
undetectable		 4e7gA-4anjA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 6 GLU A 469
ARG A 205
GLU A 231
SER A 233
 None
 1.08A 4kr3A-4anjA:
undetectable		 4kr3A-4anjA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 10 LEU A 292
ALA A 253
GLY A 315
ILE A 318
ILE A 291
 None
 1.04A 4njuB-4anjA:
undetectable		 4njuB-4anjA:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 6 VAL A1055
LEU A1053
LEU A1125
PHE A1165
 None
None
None
CR2  A1065 ( 4.2A)
 0.84A 4o1zA-4anjA:
undetectable		 4o1zA-4anjA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 12 GLY A 644
ASN A 645
ASP A 599
SER A 467
ASN A 598
 None
 1.35A 4pooB-4anjA:
3.1		 4pooB-4anjA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 6 ILE A 571
HIS A 581
ILE A 525
VAL A 547
 None
 1.00A 4zj8A-4anjA:
3.6		 4zj8A-4anjA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		5 / 10 PHE A 192
ALA A 191
VAL A 341
LEU A 263
PHE A 317
 None
 1.32A 4zmeB-4anjA:
undetectable		 4zmeB-4anjA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 7 ILE A1098
ASP A1129
GLY A1104
PHE A1100
 None
 0.89A 5h3aA-4anjA:
undetectable		 5h3aA-4anjA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		3 / 3 ILE A 103
PRO A 104
ILE A 106
 None
 0.40A 5hw8F-4anjA:
undetectable		 5hw8F-4anjA:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 6 VAL A 164
SER A 664
ILE A 488
PHE A 484
 None
 0.86A 5jw1A-4anjA:
undetectable		 5jw1A-4anjA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 6 VAL A 164
SER A 664
ILE A 488
PHE A 484
 None
 0.89A 5jw1B-4anjA:
undetectable		 5jw1B-4anjA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		3 / 3 VAL A 149
ARG A  85
PRO A 125
 None
 0.85A 5koxA-4anjA:
undetectable		 5koxA-4anjA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Sus
scrofa) 		4 / 7 GLN A 512
ASP A 516
HIS A 551
TYR A 588
 None
 1.29A 5ov9B-4anjA:
undetectable		 5ov9B-4anjA:
18.41