SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ann'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4ann ESSB
(Staphylococcus
aureus) 		5 / 9 ILE A  86
ASP A 126
GLY A 127
PHE A 123
ASN A 100
 None
 1.46A 1i00B-4annA:
undetectable		 1i00B-4annA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 4ann ESSB
(Staphylococcus
aureus) 		4 / 7 PRO A 142
VAL A 115
ALA A 131
PHE A  58
 None
 0.89A 4lb2A-4annA:
2.0		 4lb2A-4annA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 4ann ESSB
(Staphylococcus
aureus) 		4 / 8 LEU A 136
ALA A  61
VAL A 139
TYR A  49
 None
 1.01A 5nu7A-4annA:
undetectable		 5nu7A-4annA:
20.81