SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ano'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		5 / 11 LEU A 103
VAL A 127
GLY A 126
VAL A  62
ILE A  53
 None
 0.98A 1phgA-4anoA:
undetectable		 1phgA-4anoA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		5 / 11 VAL A 125
GLY A 126
VAL A  24
ILE A  64
VAL A  62
 None
 1.18A 1phgA-4anoA:
undetectable		 1phgA-4anoA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		3 / 3 ARG A 102
ILE A 104
TRP A 136
 None
 0.91A 1qomA-4anoA:
undetectable		 1qomA-4anoA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		4 / 7 LEU A 103
VAL A 127
GLY A 126
VAL A  62
 None
 0.76A 1t88A-4anoA:
undetectable		 1t88A-4anoA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		5 / 10 LEU A   8
LEU A  12
ILE A 106
GLU A  40
LEU A 131
 None
 1.10A 1wopA-4anoA:
undetectable		 1wopA-4anoA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		4 / 8 LEU A 103
VAL A 127
GLY A 126
VAL A  62
 None
 0.65A 2a1oA-4anoA:
undetectable		 2a1oA-4anoA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		5 / 9 LEU A 103
VAL A 127
GLY A 126
VAL A  62
ILE A  53
 None
 0.88A 2a1oB-4anoA:
undetectable		 2a1oB-4anoA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		3 / 3 ARG A 102
ILE A 104
TRP A 136
 None
 1.00A 2nodB-4anoA:
undetectable		 2nodB-4anoA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		3 / 3 ARG A 102
ILE A 104
TRP A 136
 None
 0.88A 3nw2A-4anoA:
undetectable		 3nw2A-4anoA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		3 / 3 ARG A 102
ILE A 104
TRP A 136
 None
 0.93A 3nw2B-4anoA:
undetectable		 3nw2B-4anoA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		4 / 8 HIS A 124
GLU A   9
MET A  16
ILE A  25
 None
 1.23A 4cx7A-4anoA:
undetectable
4cx7B-4anoA:
undetectable		 4cx7A-4anoA:
19.80
4cx7B-4anoA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 4ano ESSB
(Geobacillus
thermodenitrific
ans) 		5 / 12 GLY A 126
ILE A 104
PHE A 105
VAL A  41
LEU A 141
 None
 1.46A 5nz0A-4anoA:
undetectable		 5nz0A-4anoA:
22.67