SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4aqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 5 TYR A 376
LEU A 478
VAL A 210
ASP A 214
 None
 1.40A 1dz6A-4aqqA:
undetectable		 1dz6A-4aqqA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 8 SER A 378
ILE A 190
VAL A 257
SER A 262
 None
 1.05A 1kb9A-4aqqA:
undetectable
1kb9C-4aqqA:
undetectable
1kb9D-4aqqA:
undetectable
1kb9E-4aqqA:
undetectable		 1kb9A-4aqqA:
22.32
1kb9C-4aqqA:
22.53
1kb9D-4aqqA:
20.83
1kb9E-4aqqA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 LYS A 124
LEU A 123
GLN A 122
LEU A 414
 None
 0.95A 1v55C-4aqqA:
undetectable
1v55J-4aqqA:
undetectable		 1v55C-4aqqA:
19.73
1v55J-4aqqA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 LYS A 124
LEU A 123
GLN A 122
LEU A 414
 None
 0.99A 1v55P-4aqqA:
undetectable
1v55W-4aqqA:
undetectable		 1v55P-4aqqA:
19.73
1v55W-4aqqA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_A_CHDA1_0
(LIVER
CARBOXYLESTERASE 1)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 5 TRP A 228
GLY A 238
LEU A 226
PRO A 293
 None
 1.20A 2dqyA-4aqqA:
undetectable		 2dqyA-4aqqA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 LYS A 124
LEU A 123
GLN A 122
LEU A 414
 None
 1.02A 2dysC-4aqqA:
undetectable
2dysJ-4aqqA:
undetectable		 2dysC-4aqqA:
19.73
2dysJ-4aqqA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 LYS A 124
LEU A 123
GLN A 122
LEU A 414
 None
 0.95A 2eijC-4aqqA:
undetectable
2eijJ-4aqqA:
undetectable		 2eijC-4aqqA:
19.73
2eijJ-4aqqA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 LYS A 124
LEU A 123
GLN A 122
LEU A 414
 None
 1.00A 2eijP-4aqqA:
undetectable
2eijW-4aqqA:
undetectable		 2eijP-4aqqA:
19.73
2eijW-4aqqA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 8 LYS A 124
LEU A 123
GLN A 122
LEU A 414
 None
 0.91A 2eilC-4aqqA:
undetectable
2eilJ-4aqqA:
undetectable		 2eilC-4aqqA:
19.73
2eilJ-4aqqA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 LYS A 124
LEU A 123
GLN A 122
LEU A 414
 None
 0.93A 2einC-4aqqA:
undetectable
2einJ-4aqqA:
undetectable		 2einC-4aqqA:
19.73
2einJ-4aqqA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 LYS A 124
LEU A 123
GLN A 122
LEU A 414
 None
 1.00A 2zxwC-4aqqA:
undetectable
2zxwJ-4aqqA:
undetectable		 2zxwC-4aqqA:
19.73
2zxwJ-4aqqA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 4 PRO A 355
LEU A 234
ILE A 235
ARG A 225
 None
 1.37A 4f4dA-4aqqA:
undetectable		 4f4dA-4aqqA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 8 TYR A 376
LEU A 478
ASP A 214
VAL A 147
 None
 1.04A 4l4bA-4aqqA:
undetectable		 4l4bA-4aqqA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 ARG A 460
PHE A 224
ASP A 220
TYR A 242
 None
 1.46A 5a06A-4aqqA:
undetectable		 5a06A-4aqqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 ARG A 460
PHE A 224
ASP A 220
TYR A 242
 None
 1.47A 5a06C-4aqqA:
undetectable		 5a06C-4aqqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 ARG A 460
PHE A 224
ASP A 220
TYR A 242
 None
 1.46A 5a06D-4aqqA:
undetectable		 5a06D-4aqqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 ARG A 460
PHE A 224
ASP A 220
TYR A 242
 None
 1.45A 5a06E-4aqqA:
undetectable		 5a06E-4aqqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 7 ARG A 460
PHE A 224
ASP A 220
TYR A 242
 None
 1.44A 5a06F-4aqqA:
undetectable		 5a06F-4aqqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		3 / 3 ASN A 366
SER A 213
ARG A 151
 None
 0.86A 5b2qA-4aqqA:
undetectable		 5b2qA-4aqqA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		5 / 12 ILE A 197
ALA A 196
PHE A 219
LEU A 179
GLY A 216
 None
 1.17A 5i71A-4aqqA:
undetectable		 5i71A-4aqqA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 8 SER A 413
THR A 515
THR A 517
PRO A 421
 None
 1.01A 5jhdE-4aqqA:
undetectable
5jhdG-4aqqA:
undetectable		 5jhdE-4aqqA:
19.05
5jhdG-4aqqA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		3 / 3 ARG A 222
PRO A 481
ASN A 194
 None
 1.09A 5jwaA-4aqqA:
undetectable
5jwaH-4aqqA:
undetectable		 5jwaA-4aqqA:
21.71
5jwaH-4aqqA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		3 / 3 THR A 221
PRO A 481
ASP A 191
 None
 0.88A 5l8dB-4aqqA:
undetectable		 5l8dB-4aqqA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		3 / 3 THR A 221
PRO A 481
ASP A 191
 None
 0.88A 5mwuB-4aqqA:
undetectable		 5mwuB-4aqqA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 8 LEU A  71
VAL A  95
MET A 417
HIS A 499
 None
 0.93A 5nu7A-4aqqA:
undetectable		 5nu7A-4aqqA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4aqq L2 PROTEIN III
(PENTON BASE)
(Human
mastadenovirus
B) 		4 / 8 TYR A 376
LEU A 478
ASP A 214
VAL A 147
 None
 1.00A 6cp4A-4aqqA:
undetectable		 6cp4A-4aqqA:
22.63