SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4arp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4arp PESTICIN
(Yersinia
pestis) 		3 / 3 GLN A 301
ILE A 166
HIS A 269
 None
 0.73A 1fm9A-4arpA:
undetectable		 1fm9A-4arpA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4arp PESTICIN
(Yersinia
pestis) 		3 / 3 GLN A 301
ILE A 166
HIS A 269
 None
 0.74A 1k74A-4arpA:
undetectable		 1k74A-4arpA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 4arp PESTICIN
(Yersinia
pestis) 		5 / 12 GLY A 203
ASN A 181
HIS A 185
PHE A 202
VAL A 206
 None
 1.33A 1qu3A-4arpA:
undetectable		 1qu3A-4arpA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 4arp PESTICIN
(Yersinia
pestis) 		4 / 6 ALA A 256
LEU A 258
ILE A 225
SER A 252
 None
 0.99A 1sbrA-4arpA:
undetectable
1sbrB-4arpA:
undetectable		 1sbrA-4arpA:
20.06
1sbrB-4arpA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 4arp PESTICIN
(Yersinia
pestis) 		3 / 3 GLY A 104
GLU A  66
ASP A 103
 None
 0.41A 2b25B-4arpA:
undetectable		 2b25B-4arpA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 4arp PESTICIN
(Yersinia
pestis) 		5 / 10 THR A  95
VAL A 110
VAL A 147
ILE A 140
VAL A 141
 None
 1.30A 2qboA-4arpA:
undetectable		 2qboA-4arpA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4arp PESTICIN
(Yersinia
pestis) 		4 / 8 GLN A 301
ARG A 339
MET A 336
SER A 197
 None
 1.09A 2xytH-4arpA:
undetectable		 2xytH-4arpA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 4arp PESTICIN
(Yersinia
pestis) 		5 / 11 ASN A 149
VAL A 147
PHE A 159
LEU A 156
GLU A  97
 None
 1.32A 3bgrA-4arpA:
undetectable
3bgrB-4arpA:
undetectable		 3bgrA-4arpA:
23.20
3bgrB-4arpA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 4arp PESTICIN
(Yersinia
pestis) 		3 / 3 TYR A  26
TYR A  55
GLU A 114
 None
 0.95A 3pfgA-4arpA:
undetectable		 3pfgA-4arpA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4arp PESTICIN
(Yersinia
pestis) 		5 / 12 GLU A 128
ASP A 125
ILE A 153
LEU A 156
SER A  21
 None
 1.23A 4djfB-4arpA:
undetectable		 4djfB-4arpA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4arp PESTICIN
(Yersinia
pestis) 		4 / 6 ILE A 153
ASN A 152
GLU A 101
VAL A 147
 None
 1.04A 4ejwB-4arpA:
undetectable		 4ejwB-4arpA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4arp PESTICIN
(Yersinia
pestis) 		5 / 11 LEU A 346
ASP A 352
GLN A 348
ALA A 345
VAL A 326
 None
 1.27A 4uuuA-4arpA:
undetectable
4uuuB-4arpA:
undetectable		 4uuuA-4arpA:
19.24
4uuuB-4arpA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4arp PESTICIN
(Yersinia
pestis) 		5 / 11 LEU A 346
ASP A 352
GLN A 348
ALA A 345
VAL A 326
 None
 1.24A 4uuuB-4arpA:
undetectable		 4uuuB-4arpA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4arp PESTICIN
(Yersinia
pestis) 		3 / 3 MET A 234
GLN A 210
ARG A 211
 None
 1.08A 5m35B-4arpA:
undetectable		 5m35B-4arpA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4arp PESTICIN
(Yersinia
pestis) 		3 / 3 MET A 234
GLN A 210
ARG A 211
 None
 1.04A 5m36A-4arpA:
undetectable		 5m36A-4arpA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4arp PESTICIN
(Yersinia
pestis) 		3 / 3 GLN A 301
ILE A 166
HIS A 269
 None
 0.68A 5z12B-4arpA:
undetectable		 5z12B-4arpA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4arp PESTICIN
(Yersinia
pestis) 		3 / 3 MET A 234
GLN A 210
ARG A 211
 None
 1.06A 6fn9A-4arpA:
undetectable		 6fn9A-4arpA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4arp PESTICIN
(Yersinia
pestis) 		3 / 3 MET A 234
GLN A 210
ARG A 211
 None
 1.10A 6fnaB-4arpA:
undetectable		 6fnaB-4arpA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4arp PESTICIN
(Yersinia
pestis) 		3 / 3 MET A 234
GLN A 210
ARG A 211
 None
 1.05A 6fnbA-4arpA:
undetectable		 6fnbA-4arpA:
21.55