SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4asm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		4 / 6 PRO B 300
ASP B 198
ASN B 200
TYR B 194
 None
 1.39A 1hpkA-4asmB:
undetectable		 1hpkA-4asmB:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		4 / 7 TYR B 194
LEU B 271
VAL B 262
GLY B 261
 None
 0.92A 1t88A-4asmB:
undetectable		 1t88A-4asmB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		4 / 8 TYR B 194
LEU B 271
VAL B 262
GLY B 261
 None
 0.83A 2a1oA-4asmB:
undetectable		 2a1oA-4asmB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		3 / 3 TRP B 202
GLU B 160
TYR B 162
 None
PEG  B1361 ( 3.7A)
None
 1.22A 2a3aA-4asmB:
undetectable		 2a3aA-4asmB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		5 / 12 LEU B 147
ILE B 145
ILE B 318
ILE B 316
VAL B 128
 None
 0.90A 2ygoA-4asmB:
undetectable		 2ygoA-4asmB:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		3 / 3 ASP B 322
SER B 332
ARG B  92
 None
 0.99A 3loqA-4asmB:
undetectable		 3loqA-4asmB:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		3 / 3 SER B 172
PHE B 174
LYS B 177
 None
 0.85A 3u88A-4asmB:
undetectable		 3u88A-4asmB:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		4 / 4 ASN B  57
VAL B  40
THR B 119
ILE B 118
 None
 0.80A 4retA-4asmB:
undetectable		 4retA-4asmB:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		4 / 4 ASN B  57
VAL B  40
THR B 119
ILE B 118
 None
 0.80A 4retC-4asmB:
undetectable		 4retC-4asmB:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		3 / 3 ARG B 133
ASP B 349
TRP B 350
 None
CA  B1359 (-3.3A)
None
 0.16A 4xdqA-4asmB:
17.6		 4xdqA-4asmB:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		5 / 9 TYR B 194
THR B 265
LEU B 271
VAL B 262
GLY B 261
 None
 1.40A 5cp4A-4asmB:
undetectable		 5cp4A-4asmB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		5 / 11 HIS B 179
HIS B 183
VAL B 184
SER B 181
ASP B 299
 PEG  B1361 (-4.2A)
None
None
None
None
 1.11A 5z0fA-4asmB:
undetectable
5z0fB-4asmB:
undetectable		 5z0fA-4asmB:
13.37
5z0fB-4asmB:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		5 / 11 HIS B 179
HIS B 183
VAL B 184
SER B 181
ASP B 299
 PEG  B1361 (-4.2A)
None
None
None
None
 1.15A 5z0gA-4asmB:
undetectable
5z0gB-4asmB:
undetectable		 5z0gA-4asmB:
13.37
5z0gB-4asmB:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4asm BETA-AGARASE D
(Zobellia
galactanivorans) 		3 / 3 TYR B 194
ASP B 193
GLN B 195
 None
None
PEG  B1361 (-3.0A)
 0.89A 6g1pA-4asmB:
undetectable		 6g1pA-4asmB:
20.45