SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4at0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AQ7_B_AG2B4_1 (TRYPSIN AERUGINOSIN 98-B)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 8	HIS A 268 ASP A 474 SER A 471 GLY A 455 GLY A 475	FAD A1493 (-4.0A) None FAD A1493 (-2.7A) FAD A1493 (-3.5A) None	1.30A	1aq7A-4at0A: undetectable	1aq7A-4at0A: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_A_IPHA802_0 (PHENOL HYDROXYLASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 10	ASP A 269 GLY A 270 MET A 275 ARG A 52 GLY A 241	None None None FAD A1493 (-4.9A) FAD A1493 (-3.6A)	1.29A	1fohA-4at0A: 13.2	1fohA-4at0A: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_B_IPHB802_0 (PHENOL HYDROXYLASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 10	ASP A 269 GLY A 270 MET A 275 ARG A 52 GLY A 241	None None None FAD A1493 (-4.9A) FAD A1493 (-3.6A)	1.26A	1fohB-4at0A: 5.2	1fohB-4at0A: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_C_IPHC802_0 (PHENOL HYDROXYLASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 10	ASP A 269 GLY A 270 MET A 275 ARG A 52 GLY A 241	None None None FAD A1493 (-4.9A) FAD A1493 (-3.6A)	1.22A	1fohC-4at0A: 6.0	1fohC-4at0A: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_D_IPHD802_0 (PHENOL HYDROXYLASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 10	ASP A 269 GLY A 270 MET A 275 ARG A 52 GLY A 241	None None None FAD A1493 (-4.9A) FAD A1493 (-3.6A)	1.25A	1fohD-4at0A: 13.8	1fohD-4at0A: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_F_TFPF211_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 7	LEU A 119 PHE A 126 LEU A 184 SER A 468	None None None ACT A1490 (-2.6A)	0.94A	1wrlE-4at0A: 0.4 1wrlF-4at0A: 0.4	1wrlE-4at0A: 10.00 1wrlF-4at0A: 10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AJV_L_COCL501_1 (ANTIBODY 7A1 FAB')	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 7	ALA A 61 TYR A 182 TYR A 29 TYR A 201	None	1.08A	2ajvH-4at0A: undetectable 2ajvL-4at0A: undetectable	2ajvH-4at0A: 18.89 2ajvL-4at0A: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJG_A_ADNA1501_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 7	ARG A 302 LYS A 409 ASN A 390 ALA A 393	None	1.32A	2ejgA-4at0A: undetectable	2ejgA-4at0A: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XAT_A_CLMA301_0 (XENOBIOTIC ACETYLTRANSFERASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	3 / 3	GLY A 148 TYR A 319 SER A 147	None	0.68A	2xatA-4at0A: undetectable	2xatA-4at0A: 16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XCT_X_CPFX1020_1 (DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 4	ARG A 164 GLY A 165 GLU A 150 SER A 476	None	1.40A	2xctS-4at0A: undetectable 2xctU-4at0A: undetectable	2xctS-4at0A: 22.77 2xctU-4at0A: 22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G2O_B_SAMB600_0 (PCZA361.24)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 12	ALA A 63 GLY A 180 LEU A 184 LEU A 62 GLY A 469	FAD A1493 (-3.3A) None None None FAD A1493 ( 3.1A)	1.10A	3g2oB-4at0A: undetectable	3g2oB-4at0A: 23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GY3_A_PNTA246_0 (CATIONIC TRYPSIN)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 11	HIS A 268 ASP A 474 SER A 471 GLY A 455 GLY A 475	FAD A1493 (-4.0A) None FAD A1493 (-2.7A) FAD A1493 (-3.5A) None	1.16A	3gy3A-4at0A: undetectable	3gy3A-4at0A: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU1_A_SAMA226_0 (SAM-DEPENDENT METHYLTRANSFERASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	6 / 12	LEU A 96 GLY A 469 VAL A 167 GLY A 64 ALA A 467 GLY A 148	None FAD A1493 ( 3.1A) None ACT A1491 ( 3.2A) None None	1.22A	3ku1A-4at0A: undetectable	3ku1A-4at0A: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU1_C_SAMC226_0 (SAM-DEPENDENT METHYLTRANSFERASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	6 / 12	LEU A 96 GLY A 469 VAL A 167 GLY A 64 ALA A 467 GLY A 148	None FAD A1493 ( 3.1A) None ACT A1491 ( 3.2A) None None	1.19A	3ku1C-4at0A: undetectable	3ku1C-4at0A: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU1_G_SAMG226_0 (SAM-DEPENDENT METHYLTRANSFERASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 12	LEU A 96 GLY A 469 VAL A 167 GLY A 64 GLY A 148	None FAD A1493 ( 3.1A) None ACT A1491 ( 3.2A) None	0.88A	3ku1G-4at0A: undetectable	3ku1G-4at0A: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O14_A_NIOA300_1 (ANTI-ECFSIGMA FACTOR, CHRR)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 7	ALA A 453 VAL A 216 VAL A 236 LEU A 238	None	0.85A	3o14A-4at0A: undetectable	3o14A-4at0A: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXY_B_SAMB6735_0 (N-LYSINE METHYLTRANSFERASE SETD6 TRANSCRIPTION FACTOR P65)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 11	ALA A 63 GLY A 64 ALA A 292 TYR A 466 PHE A 427	FAD A1493 (-3.3A) ACT A1491 ( 3.2A) None ACT A1490 ( 4.4A) FAD A1493 (-4.2A)	1.21A	3qxyB-4at0A: undetectable 3qxyQ-4at0A: undetectable	3qxyB-4at0A: 22.53 3qxyQ-4at0A: 3.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RC0_A_SAMA484_0 (N-LYSINE METHYLTRANSFERASE SETD6)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 11	ALA A 63 GLY A 64 ALA A 292 TYR A 466 PHE A 427	FAD A1493 (-3.3A) ACT A1491 ( 3.2A) None ACT A1490 ( 4.4A) FAD A1493 (-4.2A)	1.22A	3rc0A-4at0A: undetectable	3rc0A-4at0A: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RC0_B_SAMB480_0 (N-LYSINE METHYLTRANSFERASE SETD6)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 12	ALA A 63 GLY A 64 ALA A 292 TYR A 466 PHE A 427	FAD A1493 (-3.3A) ACT A1491 ( 3.2A) None ACT A1490 ( 4.4A) FAD A1493 (-4.2A)	1.19A	3rc0B-4at0A: undetectable	3rc0B-4at0A: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKA_A_SAMA400_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE H)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 12	THR A 470 GLY A 473 GLY A 455 ARG A 164 GLU A 150	None None FAD A1493 (-3.5A) None None	1.30A	3tkaA-4at0A: undetectable	3tkaA-4at0A: 24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3N_B_MIYB2001_1 (TETX2 PROTEIN)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 8	GLN A 76 HIS A 166 GLY A 70 GLY A 149	None	0.77A	3v3nB-4at0A: 11.3	3v3nB-4at0A: 22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3N_C_MIYC2001_1 (TETX2 PROTEIN)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 8	GLN A 76 HIS A 166 GLY A 70 GLY A 149	None	0.76A	3v3nC-4at0A: 9.4	3v3nC-4at0A: 22.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AT0_A_ACTA1490_0 (3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	3 / 3	GLU A 290 TYR A 466 SER A 468	ACT A1490 ( 4.4A) ACT A1490 ( 4.4A) ACT A1490 (-2.6A)	0.00A	4at0A-4at0A: 73.7	4at0A-4at0A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AT2_A_ASDA1490_1 (3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	9 / 10	GLU A 137 GLU A 290 ALA A 292 VAL A 294 TYR A 319 THR A 354 PHE A 427 TYR A 466 SER A 468	ACT A1491 (-4.2A) ACT A1490 ( 4.4A) None None None None FAD A1493 (-4.2A) ACT A1490 ( 4.4A) ACT A1490 (-2.6A)	0.47A	4at2A-4at0A: 68.5	4at2A-4at0A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AT2_A_ASDA1490_1 (3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	6 / 10	TRP A 136 GLU A 137 GLU A 290 ALA A 292 PHE A 427 TYR A 466	None ACT A1491 (-4.2A) ACT A1490 ( 4.4A) None FAD A1493 (-4.2A) ACT A1490 ( 4.4A)	1.20A	4at2A-4at0A: 68.5	4at2A-4at0A: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RN6_B_15UB301_1 (THROMBIN HEAVY CHAIN)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 12	ALA A 486 ALA A 453 VAL A 237 GLY A 450 GLY A 235	None	0.90A	4rn6B-4at0A: undetectable	4rn6B-4at0A: 20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XJE_A_TOYA202_1 (AADB)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 8	ASP A 317 GLU A 316 ILE A 304 ASP A 398	None	1.00A	4xjeA-4at0A: undetectable	4xjeA-4at0A: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZJZ_A_BEZA1001_0 (BENZOATE-COENZYME A LIGASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 8	ALA A 454 GLY A 479 ALA A 36 GLY A 33	None	0.65A	4zjzA-4at0A: undetectable	4zjzA-4at0A: 23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D4U_C_SAMC301_0 (UNCHARACTERIZED PROTEIN MJ0489)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 12	GLY A 181 LEU A 188 THR A 60 GLY A 30 ILE A 31	None None FAD A1493 (-3.6A) FAD A1493 (-3.3A) FAD A1493 (-4.6A)	0.90A	5d4uC-4at0A: undetectable	5d4uC-4at0A: 20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D4U_D_SAMD301_0 (UNCHARACTERIZED PROTEIN MJ0489)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 12	GLY A 181 LEU A 188 THR A 60 GLY A 30 ILE A 31	None None FAD A1493 (-3.6A) FAD A1493 (-3.3A) FAD A1493 (-4.6A)	0.89A	5d4uD-4at0A: undetectable	5d4uD-4at0A: 20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_B_BEZB1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 6	GLY A 71 SER A 112 VAL A 113 HIS A 166	None	1.14A	5ewuB-4at0A: undetectable	5ewuB-4at0A: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_ACTA405_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	3 / 3	GLN A 298 THR A 352 ASP A 296	None	0.92A	5k9dA-4at0A: undetectable	5k9dA-4at0A: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KMF_A_6U9A1301_1 (ION TRANSPORT PROTEIN)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 6	THR A 73 GLY A 70 TYR A 108 ILE A 105	None	0.82A	5kmfA-4at0A: undetectable 5kmfC-4at0A: undetectable	5kmfA-4at0A: 18.20 5kmfC-4at0A: 18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOX_A_RFPA502_1 (PENTACHLOROPHENOL 4-MONOOXYGENASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 12	GLY A 176 GLY A 475 ILE A 31 GLY A 180 GLY A 179	None None FAD A1493 (-4.6A) None None	0.94A	5koxA-4at0A: 14.0	5koxA-4at0A: 25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L8D_B_ACTB601_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	3 / 3	THR A 351 PRO A 139 ASP A 142	None	0.83A	5l8dB-4at0A: undetectable	5l8dB-4at0A: 21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWU_B_ACTB601_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	3 / 3	THR A 351 PRO A 139 ASP A 142	None	0.83A	5mwuB-4at0A: undetectable	5mwuB-4at0A: 21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD6_A_STIA603_1 (TYROSINE-PROTEIN KINASE ABL1)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	4 / 5	LEU A 305 TYR A 313 ILE A 158 GLY A 324	None	1.07A	6hd6A-4at0A: undetectable	6hd6A-4at0A: 11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6QXS_D_FOZD403_0 (THYMIDYLATE SYNTHASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 12	LEU A 337 LEU A 400 LEU A 382 GLY A 310 ASN A 307	None	1.26A	6qxsD-4at0A: undetectable	6qxsD-4at0A: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6QYA_D_FOZD401_0 (THYMIDYLATE SYNTHASE)	4at0	3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E (Rhodococcus jostii)	5 / 12	LEU A 337 LEU A 400 LEU A 382 GLY A 310 ASN A 307	None	1.25A	6qyaD-4at0A: undetectable	6qyaD-4at0A: 19.34

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AQ7_B_AG2B4_1","TRYPSIN;AERUGINOSIN 98-B","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"HIS A 268;ASP A 474;SER A 471;GLY A 455;GLY A 475","FAD A1493 (-4.0A);None;FAD A1493 (-2.7A);FAD A1493 (-3.5A);None","1.30A","1aq7A-4at0A:undetectable","1aq7A-4at0A:16.88"],["1FOH_A_IPHA802_0","PHENOL HYDROXYLASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"ASP A 269;GLY A 270;MET A 275;ARG A  52;GLY A 241","None;None;None;FAD A1493 (-4.9A);FAD A1493 (-3.6A)","1.29A","1fohA-4at0A:13.2","1fohA-4at0A:21.31"],["1FOH_B_IPHB802_0","PHENOL HYDROXYLASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"ASP A 269;GLY A 270;MET A 275;ARG A  52;GLY A 241","None;None;None;FAD A1493 (-4.9A);FAD A1493 (-3.6A)","1.26A","1fohB-4at0A:5.2","1fohB-4at0A:21.31"],["1FOH_C_IPHC802_0","PHENOL HYDROXYLASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"ASP A 269;GLY A 270;MET A 275;ARG A  52;GLY A 241","None;None;None;FAD A1493 (-4.9A);FAD A1493 (-3.6A)","1.22A","1fohC-4at0A:6.0","1fohC-4at0A:21.31"],["1FOH_D_IPHD802_0","PHENOL HYDROXYLASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"ASP A 269;GLY A 270;MET A 275;ARG A  52;GLY A 241","None;None;None;FAD A1493 (-4.9A);FAD A1493 (-3.6A)","1.25A","1fohD-4at0A:13.8","1fohD-4at0A:21.31"],["1WRL_F_TFPF211_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES;TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"LEU A 119;PHE A 126;LEU A 184;SER A 468","None;None;None;ACT A1490 (-2.6A)","0.94A","1wrlE-4at0A:0.4;1wrlF-4at0A:0.4","1wrlE-4at0A:10.00;1wrlF-4at0A:10.00"],["2AJV_L_COCL501_1","ANTIBODY 7A1 FAB';ANTIBODY 7A1 FAB'","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"ALA A  61;TYR A 182;TYR A  29;TYR A 201","None","1.08A","2ajvH-4at0A:undetectable;2ajvL-4at0A:undetectable","2ajvH-4at0A:18.89;2ajvL-4at0A:18.09"],["2EJG_A_ADNA1501_1","235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"ARG A 302;LYS A 409;ASN A 390;ALA A 393","None","1.32A","2ejgA-4at0A:undetectable","2ejgA-4at0A:19.01"],["2XAT_A_CLMA301_0","XENOBIOTIC ACETYLTRANSFERASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",3,"GLY A 148;TYR A 319;SER A 147","None","0.68A","2xatA-4at0A:undetectable","2xatA-4at0A:16.86"],["2XCT_X_CPFX1020_1","DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"ARG A 164;GLY A 165;GLU A 150;SER A 476","None","1.40A","2xctS-4at0A:undetectable;2xctU-4at0A:undetectable","2xctS-4at0A:22.77;2xctU-4at0A:22.77"],["3G2O_B_SAMB600_0","PCZA361.24","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"ALA A  63;GLY A 180;LEU A 184;LEU A  62;GLY A 469","FAD A1493 (-3.3A);None;None;None;FAD A1493 ( 3.1A)","1.10A","3g2oB-4at0A:undetectable","3g2oB-4at0A:23.98"],["3GY3_A_PNTA246_0","CATIONIC TRYPSIN","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"HIS A 268;ASP A 474;SER A 471;GLY A 455;GLY A 475","FAD A1493 (-4.0A);None;FAD A1493 (-2.7A);FAD A1493 (-3.5A);None","1.16A","3gy3A-4at0A:undetectable","3gy3A-4at0A:16.88"],["3KU1_A_SAMA226_0","SAM-DEPENDENT METHYLTRANSFERASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",6,"LEU A  96;GLY A 469;VAL A 167;GLY A  64;ALA A 467;GLY A 148","None;FAD A1493 ( 3.1A);None;ACT A1491 ( 3.2A);None;None","1.22A","3ku1A-4at0A:undetectable","3ku1A-4at0A:19.02"],["3KU1_C_SAMC226_0","SAM-DEPENDENT METHYLTRANSFERASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",6,"LEU A  96;GLY A 469;VAL A 167;GLY A  64;ALA A 467;GLY A 148","None;FAD A1493 ( 3.1A);None;ACT A1491 ( 3.2A);None;None","1.19A","3ku1C-4at0A:undetectable","3ku1C-4at0A:19.02"],["3KU1_G_SAMG226_0","SAM-DEPENDENT METHYLTRANSFERASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"LEU A  96;GLY A 469;VAL A 167;GLY A  64;GLY A 148","None;FAD A1493 ( 3.1A);None;ACT A1491 ( 3.2A);None","0.88A","3ku1G-4at0A:undetectable","3ku1G-4at0A:19.02"],["3O14_A_NIOA300_1","ANTI-ECFSIGMA FACTOR, CHRR","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"ALA A 453;VAL A 216;VAL A 236;LEU A 238","None","0.85A","3o14A-4at0A:undetectable","3o14A-4at0A:19.25"],["3QXY_B_SAMB6735_0","N-LYSINE METHYLTRANSFERASE SETD6;TRANSCRIPTION FACTOR P65","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"ALA A  63;GLY A  64;ALA A 292;TYR A 466;PHE A 427","FAD A1493 (-3.3A);ACT A1491 ( 3.2A);None;ACT A1490 ( 4.4A);FAD A1493 (-4.2A)","1.21A","3qxyB-4at0A:undetectable;3qxyQ-4at0A:undetectable","3qxyB-4at0A:22.53;3qxyQ-4at0A:3.67"],["3RC0_A_SAMA484_0","N-LYSINE METHYLTRANSFERASE SETD6","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"ALA A  63;GLY A  64;ALA A 292;TYR A 466;PHE A 427","FAD A1493 (-3.3A);ACT A1491 ( 3.2A);None;ACT A1490 ( 4.4A);FAD A1493 (-4.2A)","1.22A","3rc0A-4at0A:undetectable","3rc0A-4at0A:22.53"],["3RC0_B_SAMB480_0","N-LYSINE METHYLTRANSFERASE SETD6","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"ALA A  63;GLY A  64;ALA A 292;TYR A 466;PHE A 427","FAD A1493 (-3.3A);ACT A1491 ( 3.2A);None;ACT A1490 ( 4.4A);FAD A1493 (-4.2A)","1.19A","3rc0B-4at0A:undetectable","3rc0B-4at0A:22.53"],["3TKA_A_SAMA400_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE H","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"THR A 470;GLY A 473;GLY A 455;ARG A 164;GLU A 150","None;None;FAD A1493 (-3.5A);None;None","1.30A","3tkaA-4at0A:undetectable","3tkaA-4at0A:24.62"],["3V3N_B_MIYB2001_1","TETX2 PROTEIN","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"GLN A  76;HIS A 166;GLY A  70;GLY A 149","None","0.77A","3v3nB-4at0A:11.3","3v3nB-4at0A:22.85"],["3V3N_C_MIYC2001_1","TETX2 PROTEIN","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"GLN A  76;HIS A 166;GLY A  70;GLY A 149","None","0.76A","3v3nC-4at0A:9.4","3v3nC-4at0A:22.85"],["4AT0_A_ACTA1490_0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",3,"GLU A 290;TYR A 466;SER A 468","ACT A1490 ( 4.4A);ACT A1490 ( 4.4A);ACT A1490 (-2.6A)","0.00A","4at0A-4at0A:73.7","4at0A-4at0A:100.00"],["4AT2_A_ASDA1490_1","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",9,"GLU A 137;GLU A 290;ALA A 292;VAL A 294;TYR A 319;THR A 354;PHE A 427;TYR A 466;SER A 468","ACT A1491 (-4.2A);ACT A1490 ( 4.4A);None;None;None;None;FAD A1493 (-4.2A);ACT A1490 ( 4.4A);ACT A1490 (-2.6A)","0.47A","4at2A-4at0A:68.5","4at2A-4at0A:100.00"],["4AT2_A_ASDA1490_1","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",6,"TRP A 136;GLU A 137;GLU A 290;ALA A 292;PHE A 427;TYR A 466","None;ACT A1491 (-4.2A);ACT A1490 ( 4.4A);None;FAD A1493 (-4.2A);ACT A1490 ( 4.4A)","1.20A","4at2A-4at0A:68.5","4at2A-4at0A:100.00"],["4RN6_B_15UB301_1","THROMBIN HEAVY CHAIN","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"ALA A 486;ALA A 453;VAL A 237;GLY A 450;GLY A 235","None","0.90A","4rn6B-4at0A:undetectable","4rn6B-4at0A:20.89"],["4XJE_A_TOYA202_1","AADB","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"ASP A 317;GLU A 316;ILE A 304;ASP A 398","None","1.00A","4xjeA-4at0A:undetectable","4xjeA-4at0A:19.02"],["4ZJZ_A_BEZA1001_0","BENZOATE-COENZYME A LIGASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"ALA A 454;GLY A 479;ALA A  36;GLY A  33","None","0.65A","4zjzA-4at0A:undetectable","4zjzA-4at0A:23.19"],["5D4U_C_SAMC301_0","UNCHARACTERIZED PROTEIN MJ0489","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"GLY A 181;LEU A 188;THR A  60;GLY A  30;ILE A  31","None;None;FAD A1493 (-3.6A);FAD A1493 (-3.3A);FAD A1493 (-4.6A)","0.90A","5d4uC-4at0A:undetectable","5d4uC-4at0A:20.91"],["5D4U_D_SAMD301_0","UNCHARACTERIZED PROTEIN MJ0489","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"GLY A 181;LEU A 188;THR A  60;GLY A  30;ILE A  31","None;None;FAD A1493 (-3.6A);FAD A1493 (-3.3A);FAD A1493 (-4.6A)","0.89A","5d4uD-4at0A:undetectable","5d4uD-4at0A:20.91"],["5EWU_B_BEZB1401_0","MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"GLY A  71;SER A 112;VAL A 113;HIS A 166","None","1.14A","5ewuB-4at0A:undetectable","5ewuB-4at0A:19.25"],["5K9D_A_ACTA405_0","DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",3,"GLN A 298;THR A 352;ASP A 296","None","0.92A","5k9dA-4at0A:undetectable","5k9dA-4at0A:22.38"],["5KMF_A_6U9A1301_1","ION TRANSPORT PROTEIN;ION TRANSPORT PROTEIN","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"THR A  73;GLY A  70;TYR A 108;ILE A 105","None","0.82A","5kmfA-4at0A:undetectable;5kmfC-4at0A:undetectable","5kmfA-4at0A:18.20;5kmfC-4at0A:18.20"],["5KOX_A_RFPA502_1","PENTACHLOROPHENOL 4-MONOOXYGENASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"GLY A 176;GLY A 475;ILE A  31;GLY A 180;GLY A 179","None;None;FAD A1493 (-4.6A);None;None","0.94A","5koxA-4at0A:14.0","5koxA-4at0A:25.54"],["5L8D_B_ACTB601_0","NICKEL-BINDING PERIPLASMIC PROTEIN","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",3,"THR A 351;PRO A 139;ASP A 142","None","0.83A","5l8dB-4at0A:undetectable","5l8dB-4at0A:21.09"],["5MWU_B_ACTB601_0","NICKEL-BINDING PERIPLASMIC PROTEIN","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",3,"THR A 351;PRO A 139;ASP A 142","None","0.83A","5mwuB-4at0A:undetectable","5mwuB-4at0A:21.09"],["6HD6_A_STIA603_1","TYROSINE-PROTEIN KINASE ABL1","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",4,"LEU A 305;TYR A 313;ILE A 158;GLY A 324","None","1.07A","6hd6A-4at0A:undetectable","6hd6A-4at0A:11.67"],["6QXS_D_FOZD403_0","THYMIDYLATE SYNTHASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"LEU A 337;LEU A 400;LEU A 382;GLY A 310;ASN A 307","None","1.26A","6qxsD-4at0A:undetectable","6qxsD-4at0A:19.34"],["6QYA_D_FOZD401_0","THYMIDYLATE SYNTHASE","4at0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","Rhodococcus jostii",5,"LEU A 337;LEU A 400;LEU A 382;GLY A 310;ASN A 307","None","1.25A","6qyaD-4at0A:undetectable","6qyaD-4at0A:19.34"]]