SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4atg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 4atg TAF6
(Antonospora
locustae) 		5 / 9 LEU A 319
ILE A 318
VAL A 255
GLY A 311
ALA A 270
 None
 1.07A 1e7aA-4atgA:
2.1		 1e7aA-4atgA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 4atg TAF6
(Antonospora
locustae) 		4 / 7 THR A 279
TYR A 280
TYR A 284
LEU A 287
 None
None
NHE  A 400 (-4.7A)
None
 1.03A 1qzrA-4atgA:
undetectable		 1qzrA-4atgA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 4atg TAF6
(Antonospora
locustae) 		4 / 7 THR A 279
TYR A 280
TYR A 284
LEU A 287
 None
None
NHE  A 400 (-4.7A)
None
 1.02A 1qzrB-4atgA:
undetectable		 1qzrB-4atgA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 4atg TAF6
(Antonospora
locustae) 		4 / 6 PHE A 216
SER A 259
GLY A 257
THR A 253
 None
None
None
NHE  A 401 (-4.2A)
 1.24A 2f7fA-4atgA:
undetectable		 2f7fA-4atgA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4atg TAF6
(Antonospora
locustae) 		4 / 7 TYR A 335
GLY A 311
ALA A 312
LEU A 316
 None
 0.61A 2wekB-4atgA:
undetectable		 2wekB-4atgA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4atg TAF6
(Antonospora
locustae) 		5 / 12 LEU A 222
LEU A 211
ILE A 247
ILE A 205
LEU A 228
 None
 1.19A 4j24B-4atgA:
undetectable		 4j24B-4atgA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 4atg TAF6
(Antonospora
locustae) 		5 / 12 LEU A 222
LEU A 211
ILE A 247
ILE A 205
LEU A 228
 None
 1.23A 4j24C-4atgA:
undetectable		 4j24C-4atgA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4atg TAF6
(Antonospora
locustae) 		5 / 12 LEU A 222
LEU A 211
ILE A 247
ILE A 205
LEU A 228
 None
 1.23A 4j26B-4atgA:
undetectable		 4j26B-4atgA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4atg TAF6
(Antonospora
locustae) 		5 / 12 LEU A 244
ILE A 240
ILE A 175
TYR A 171
ILE A 205
 None
 1.06A 5y2tB-4atgA:
undetectable		 5y2tB-4atgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 4atg TAF6
(Antonospora
locustae) 		3 / 3 TRP A 299
ILE A 328
GLU A 333
 None
 0.77A 6hcxA-4atgA:
undetectable		 6hcxA-4atgA:
19.63