SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ato'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4ato TOXN
(Bacillus
thuringiensis) 		5 / 9 PHE A   9
VAL A  40
LEU A  82
PHE A  63
LEU A 121
 None
None
None
U  G   4 ( 4.9A)
None
 1.31A 1wrkA-4atoA:
undetectable
1wrkB-4atoA:
undetectable		 1wrkA-4atoA:
15.46
1wrkB-4atoA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4ato TOXN
(Bacillus
thuringiensis) 		4 / 5 PRO A   7
VAL A  40
THR A 104
GLY A 111
 None
 1.01A 3elzB-4atoA:
undetectable		 3elzB-4atoA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4ato TOXN
(Bacillus
thuringiensis) 		4 / 7 TYR A  16
ILE A  88
PRO A  91
HIS A  49
 None
 1.10A 4g5jA-4atoA:
undetectable		 4g5jA-4atoA:
21.88