SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4au0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 ALA A 280
ALA A 279
GLN A 281
LEU A 336
VAL A 323
 None
 0.99A 1xiuA-4au0A:
undetectable		 1xiuA-4au0A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 TYR A 317
ASP A 401
ASN A 302
HIS A 266
ILE A 311
 None
None
None
BGC  A 601 (-4.0A)
None
 1.41A 1xvaB-4au0A:
undetectable		 1xvaB-4au0A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		3 / 3 ARG A 353
ASP A 419
ASN A 369
 None
 0.89A 2zzmA-4au0A:
undetectable		 2zzmA-4au0A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 THR A 301
GLY A 265
GLY A 298
ASN A 302
LEU A 270
 None
 1.14A 3eeyA-4au0A:
undetectable		 3eeyA-4au0A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 THR A 301
GLY A 265
GLY A 298
ASN A 302
LEU A 270
 None
 1.17A 3eeyB-4au0A:
undetectable		 3eeyB-4au0A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 THR A 301
GLY A 265
GLY A 298
ASN A 302
LEU A 270
 None
 1.15A 3eeyC-4au0A:
undetectable		 3eeyC-4au0A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 THR A 301
GLY A 265
GLY A 298
ASN A 302
LEU A 270
 None
 1.13A 3eeyD-4au0A:
undetectable		 3eeyD-4au0A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 THR A 301
GLY A 265
GLY A 298
ASN A 302
LEU A 270
 None
 1.17A 3eeyH-4au0A:
undetectable		 3eeyH-4au0A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 THR A 301
GLY A 265
GLY A 298
ASN A 302
LEU A 270
 None
 1.18A 3eeyI-4au0A:
undetectable		 3eeyI-4au0A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 SER A 181
TRP A 135
TYR A 169
ALA A 304
GLY A 398
 None
None
None
BGC  A 602 ( 4.4A)
None
 1.34A 4j7xA-4au0A:
3.2		 4j7xA-4au0A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 9 VAL A 127
ALA A 126
GLY A 374
PHE A 375
SER A 445
 None
 1.24A 4mm5A-4au0A:
undetectable		 4mm5A-4au0A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 9 VAL A 127
ALA A 126
GLY A 374
PHE A 375
SER A 445
 None
 1.18A 4mmbA-4au0A:
undetectable		 4mmbA-4au0A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 9 VAL A 127
ALA A 126
GLY A 374
PHE A 375
SER A 445
 None
 1.22A 4mmeB-4au0A:
undetectable		 4mmeB-4au0A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 9 VAL A 127
ALA A 126
GLY A 374
PHE A 375
SER A 445
 None
 1.26A 4mmfA-4au0A:
undetectable		 4mmfA-4au0A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 9 VAL A 127
ALA A 126
GLY A 374
PHE A 375
SER A 445
 None
 1.24A 4mmfB-4au0A:
undetectable		 4mmfB-4au0A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		4 / 7 CYH A 245
ILE A 246
PRO A 172
ILE A 187
 None
 0.98A 4w5oA-4au0A:
undetectable		 4w5oA-4au0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		4 / 6 CYH A 245
ILE A 246
ILE A 187
ASP A 173
 None
 1.18A 4w5qA-4au0A:
undetectable		 4w5qA-4au0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		4 / 6 CYH A 245
ILE A 246
ILE A 187
ASP A 173
 None
 1.16A 4w5tA-4au0A:
undetectable		 4w5tA-4au0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 GLU A 219
ASP A 263
LEU A 299
ALA A 279
ASP A 175
 None
None
None
None
BGC  A 602 (-3.1A)
 1.04A 4xe5A-4au0A:
undetectable		 4xe5A-4au0A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		4 / 6 CYH A 245
ILE A 246
ILE A 187
ASP A 173
 None
 1.16A 4z4cA-4au0A:
undetectable		 4z4cA-4au0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		4 / 6 CYH A 245
ILE A 246
ILE A 187
ASP A 173
 None
 1.17A 4z4dA-4au0A:
undetectable		 4z4dA-4au0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		4 / 7 CYH A 245
ILE A 246
PRO A 172
ILE A 187
 None
 0.99A 4z4eA-4au0A:
undetectable		 4z4eA-4au0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		4 / 7 CYH A 245
ILE A 246
PRO A 172
ILE A 187
 None
 0.98A 4z4gA-4au0A:
undetectable		 4z4gA-4au0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		4 / 6 VAL A 250
ALA A 290
VAL A 286
TYR A 287
 None
None
NAG  A 501 ( 4.5A)
None
 0.83A 5i8fA-4au0A:
undetectable		 5i8fA-4au0A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		4 / 6 GLY A 183
ASP A 263
ILE A 246
TYR A 242
 None
 1.11A 5iwuA-4au0A:
undetectable		 5iwuA-4au0A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		5 / 12 ALA A 280
ALA A 279
GLN A 281
LEU A 336
VAL A 323
 None
 0.96A 5uanA-4au0A:
undetectable		 5uanA-4au0A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 4au0 EXOGLUCANASE 2
(Trichoderma
reesei) 		4 / 6 CYH A 245
ILE A 246
ILE A 187
ASP A 173
 None
 1.16A 6cbdA-4au0A:
undetectable		 6cbdA-4au0A:
16.80