SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4au7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
4 / 6 LEU A 204
ILE A 207
ASP A 184
PRO A 187
None
1.22A 1ditH-4au7A:
undetectable
1ditP-4au7A:
undetectable
1ditH-4au7A:
21.95
1ditP-4au7A:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 TYR A 217
PHE A 191
VAL A 201
LEU A 138
ALA A 179
None
1.49A 1e3vA-4au7A:
undetectable
1e3vA-4au7A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
4 / 8 PHE A 106
ILE A 108
PHE A 191
GLY A 176
None
0.65A 2qwxA-4au7A:
undetectable
2qwxB-4au7A:
undetectable
2qwxA-4au7A:
22.86
2qwxB-4au7A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
4 / 8 PHE A 106
ILE A 108
PHE A 191
GLY A 176
None
0.66A 2qx4A-4au7A:
undetectable
2qx4B-4au7A:
undetectable
2qx4A-4au7A:
23.68
2qx4B-4au7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
4 / 7 THR A  19
VAL A  22
ILE A 108
THR A  31
None
0.84A 3deuA-4au7A:
undetectable
3deuA-4au7A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OOI_A_SAMA237_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-36 AND H4
LYSINE-20 SPECIFIC)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
CYH A 229
CYH A 231
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
ZN  A1248 ( 2.3A)
ZN  A1248 ( 2.2A)
0.30A 3ooiA-4au7A:
7.7
3ooiA-4au7A:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
4 / 5 PHE A 180
ILE A 108
GLY A 176
HIS A  32
None
None
None
SAH  A1247 (-3.6A)
1.01A 3r0lD-4au7A:
undetectable
3r0lD-4au7A:
18.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQ4_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 GLY A 156
SER A 161
HIS A 183
TYR A 217
CYH A 229
None
None
SAH  A1247 (-4.6A)
None
ZN  A1248 ( 2.3A)
1.28A 3rq4A-4au7A:
37.0
3rq4A-4au7A:
93.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQ4_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
11 / 12 TYR A 114
GLU A 117
GLY A 120
SER A 161
ASN A 182
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.2A)
None
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.47A 3rq4A-4au7A:
37.0
3rq4A-4au7A:
93.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQ4_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 TYR A 114
MET A 116
GLY A 120
GLU A 230
CYH A 229
SAH  A1247 ( 3.6A)
EDO  A1251 (-4.4A)
SAH  A1247 (-3.2A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.3A)
1.33A 3rq4A-4au7A:
37.0
3rq4A-4au7A:
93.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
11 / 12 TYR A 114
GLY A 120
ALA A 121
PHE A 160
ASN A 182
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.29A 3s8pA-4au7A:
34.0
3s8pA-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
11 / 12 TYR A 114
GLY A 120
ALA A 121
SER A 161
ASN A 182
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.61A 3s8pA-4au7A:
34.0
3s8pA-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
11 / 12 TYR A 114
GLU A 117
GLY A 120
ALA A 121
PHE A 160
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.36A 3s8pB-4au7A:
8.5
3s8pB-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
11 / 12 TYR A 114
GLU A 117
GLY A 120
ALA A 121
SER A 161
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.66A 3s8pB-4au7A:
8.5
3s8pB-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
8 / 12 TYR A 114
GLU A 117
GLY A 120
PHE A 160
HIS A 183
TYR A 217
GLU A 230
CYH A 229
SAH  A1247 ( 3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.2A)
None
SAH  A1247 (-4.6A)
None
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.3A)
1.48A 3s8pB-4au7A:
8.5
3s8pB-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BUP_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
12 / 12 TYR A 114
GLU A 117
GLY A 120
ALA A 121
SER A 161
ASN A 182
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.68A 4bupA-4au7A:
32.5
4bupA-4au7A:
59.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
10 / 12 TYR A 114
GLY A 120
ALA A 121
PHE A 160
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.33A 4bupB-4au7A:
34.0
4bupB-4au7A:
59.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
10 / 12 TYR A 114
GLY A 120
ALA A 121
SER A 161
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.67A 4bupB-4au7A:
34.0
4bupB-4au7A:
59.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
3 / 3 HIS A  32
GLU A 117
ASN A 182
SAH  A1247 (-3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.1A)
0.29A 4bupB-4au7A:
34.0
4bupB-4au7A:
59.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
4 / 7 TRP A 174
ILE A 181
VAL A 192
PHE A 106
None
1.28A 4iarA-4au7A:
undetectable
4iarA-4au7A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
4 / 8 PHE A 106
ILE A 108
PHE A 191
GLY A 176
None
0.68A 4qogA-4au7A:
undetectable
4qogB-4au7A:
undetectable
4qogA-4au7A:
22.86
4qogB-4au7A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
4 / 5 TYR A  77
GLU A  13
LEU A  17
GLN A  85
None
1.49A 4qztB-4au7A:
undetectable
4qztB-4au7A:
18.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 GLY A 156
SER A 161
HIS A 183
TYR A 217
CYH A 229
None
None
SAH  A1247 (-4.6A)
None
ZN  A1248 ( 2.3A)
1.26A 5cprB-4au7A:
33.4
5cprB-4au7A:
60.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
12 / 12 TYR A 114
GLU A 117
GLY A 120
ALA A 121
PHE A 160
SER A 161
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
None
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.47A 5cprB-4au7A:
33.4
5cprB-4au7A:
60.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
8 / 12 TYR A 114
GLU A 117
GLY A 120
PHE A 160
SER A 161
HIS A 183
TYR A 217
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.2A)
None
None
SAH  A1247 (-4.6A)
None
ZN  A1248 ( 2.2A)
1.47A 5cprB-4au7A:
33.4
5cprB-4au7A:
60.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
8 / 12 TYR A 114
GLU A 117
GLY A 120
SER A 161
HIS A 183
TYR A 217
GLU A 230
CYH A 229
SAH  A1247 ( 3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.2A)
None
SAH  A1247 (-4.6A)
None
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.3A)
1.50A 5cprB-4au7A:
33.4
5cprB-4au7A:
60.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHN_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.69A 5jhnA-4au7A:
9.1
5jhnA-4au7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHN_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.67A 5jhnB-4au7A:
7.9
5jhnB-4au7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JIN_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.65A 5jinB-4au7A:
8.2
5jinB-4au7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JIY_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.67A 5jiyA-4au7A:
8.0
5jiyA-4au7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JIY_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.66A 5jiyB-4au7A:
8.2
5jiyB-4au7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JJ0_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.66A 5jj0B-4au7A:
8.0
5jj0B-4au7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
3 / 3 ASN A 182
TYR A 217
CYH A 229
SAH  A1247 (-3.1A)
None
ZN  A1248 ( 2.3A)
0.33A 5lsuB-4au7A:
8.0
5lsuB-4au7A:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0K_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.64A 5t0kA-4au7A:
8.2
5t0kA-4au7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0K_B_SAMB1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.63A 5t0kB-4au7A:
8.2
5t0kB-4au7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0M_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.65A 5t0mA-4au7A:
8.4
5t0mA-4au7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0M_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.65A 5t0mB-4au7A:
8.5
5t0mB-4au7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.62A 5ttfB-4au7A:
8.3
5ttfB-4au7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_C_SAMC1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.52A 5ttfC-4au7A:
8.2
5ttfC-4au7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_D_SAMD1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 11 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.55A 5ttfD-4au7A:
9.6
5ttfD-4au7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTG_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.62A 5ttgA-4au7A:
9.2
5ttgA-4au7A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTG_B_SAMB1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 11 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.61A 5ttgB-4au7A:
9.1
5ttgB-4au7A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUY_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.64A 5tuyB-4au7A:
9.5
5tuyB-4au7A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUZ_A_SAMA3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
6 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
CYH A 231
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
ZN  A1248 ( 2.2A)
0.57A 5tuzA-4au7A:
9.3
5tuzA-4au7A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UPD_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD3)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 11 ASN A 182
HIS A 183
TYR A 217
CYH A 229
CYH A 231
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
ZN  A1248 ( 2.3A)
ZN  A1248 ( 2.2A)
0.46A 5updA-4au7A:
7.6
5updA-4au7A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9I_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.71A 5v9iA-4au7A:
8.4
5v9iA-4au7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9I_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 11 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.64A 5v9iB-4au7A:
8.1
5v9iB-4au7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9I_C_SAMC1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 11 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.59A 5v9iC-4au7A:
8.5
5v9iC-4au7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9J_B_SAMB1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.63A 5v9jB-4au7A:
8.1
5v9jB-4au7A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSD_A_SAMA3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.65A 5vsdA-4au7A:
9.5
5vsdA-4au7A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSD_B_SAMB3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.66A 5vsdB-4au7A:
9.3
5vsdB-4au7A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSF_A_SAMA3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
PHE A 221
CYH A 229
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
None
ZN  A1248 ( 2.3A)
0.62A 5vsfA-4au7A:
9.3
5vsfA-4au7A:
22.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WBV_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
10 / 12 TYR A 114
GLY A 120
ALA A 121
PHE A 160
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.38A 5wbvA-4au7A:
33.3
5wbvA-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WBV_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
10 / 12 TYR A 114
GLY A 120
ALA A 121
SER A 161
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.63A 5wbvA-4au7A:
33.3
5wbvA-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WBV_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 TYR A 114
SER A 115
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
EDO  A1251 (-3.1A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
1.45A 5wbvA-4au7A:
33.3
5wbvA-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
3 / 3 HIS A  32
GLU A 117
ASN A 182
SAH  A1247 (-3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.1A)
0.34A 5wbvA-4au7A:
33.3
5wbvA-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
10 / 12 TYR A 114
GLY A 120
ALA A 121
PHE A 160
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.38A 5wbvB-4au7A:
32.3
5wbvB-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
10 / 12 TYR A 114
GLY A 120
ALA A 121
SER A 161
HIS A 183
TYR A 217
PHE A 222
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
SAH  A1247 (-3.2A)
SAH  A1247 (-4.1A)
None
SAH  A1247 (-4.6A)
None
SAH  A1247 (-4.0A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
0.64A 5wbvB-4au7A:
32.3
5wbvB-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 TYR A 114
SER A 115
CYH A 229
GLU A 230
CYH A 231
SAH  A1247 ( 3.6A)
EDO  A1251 (-3.1A)
ZN  A1248 ( 2.3A)
EDO  A1251 ( 2.8A)
ZN  A1248 ( 2.2A)
1.44A 5wbvB-4au7A:
32.3
5wbvB-4au7A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
3 / 3 HIS A  32
GLU A 117
ASN A 182
SAH  A1247 (-3.6A)
SAH  A1247 (-2.8A)
SAH  A1247 (-3.1A)
0.35A 5wbvB-4au7A:
32.3
5wbvB-4au7A:
60.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5K_A_SAMA805_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH6)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
CYH A 229
CYH A 231
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
ZN  A1248 ( 2.3A)
ZN  A1248 ( 2.2A)
0.34A 6a5kA-4au7A:
5.6
6a5kA-4au7A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5M_A_SAMA805_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH6)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
CYH A 229
CYH A 231
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
ZN  A1248 ( 2.3A)
ZN  A1248 ( 2.2A)
0.30A 6a5mA-4au7A:
undetectable
6a5mA-4au7A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AGO_A_SAMA2301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 11 ASN A 182
HIS A 183
TYR A 217
CYH A 229
CYH A 231
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
ZN  A1248 ( 2.3A)
ZN  A1248 ( 2.2A)
0.84A 6agoA-4au7A:
8.2
6agoA-4au7A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CEN_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD3)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 11 ASN A 182
HIS A 183
TYR A 217
CYH A 229
CYH A 231
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
ZN  A1248 ( 2.3A)
ZN  A1248 ( 2.2A)
0.46A 6cenA-4au7A:
8.0
6cenA-4au7A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6INE_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
4au7 HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2

(Mus
musculus)
5 / 12 ASN A 182
HIS A 183
TYR A 217
CYH A 229
CYH A 231
SAH  A1247 (-3.1A)
SAH  A1247 (-4.6A)
None
ZN  A1248 ( 2.3A)
ZN  A1248 ( 2.2A)
0.43A 6ineA-4au7A:
7.4
6ineA-4au7A:
22.73