SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4auq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 4auq BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 7
(Homo
sapiens) 		3 / 3 LYS B 253
ARG B 250
VAL B 260
 None
 1.01A 2r2vC-4auqB:
undetectable
2r2vD-4auqB:
undetectable		 2r2vC-4auqB:
19.35
2r2vD-4auqB:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 4auq BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 7
(Homo
sapiens) 		3 / 3 ARG B 250
VAL B 263
THR B 295
 None
 0.65A 3cyxA-4auqB:
undetectable		 3cyxA-4auqB:
18.18