SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4avo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 11 LEU A 276
GLY A 306
GLY A 304
ILE A 271
LEU A 407
 None
 1.01A 1p91A-4avoA:
undetectable		 1p91A-4avoA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 11 ALA A 365
HIS A 326
ASP A 323
ILE A 273
VAL A 404
 BGC  A 602 (-3.4A)
BGC  A 604 (-4.2A)
None
BGC  A 602 (-4.3A)
None
 1.13A 1pg2A-4avoA:
undetectable		 1pg2A-4avoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 11 LEU A 178
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.82A 1t3rB-4avoA:
undetectable		 1t3rB-4avoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 7 ARG A 458
ASN A 363
HIS A 327
ILE A 455
TRP A 391
 None
 1.50A 1tdnA-4avoA:
undetectable		 1tdnA-4avoA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 9 LEU A 178
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.95A 2avoA-4avoA:
undetectable		 2avoA-4avoA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		4 / 8 LEU A 178
ASN A 153
HIS A 200
ALA A 183
 None
 0.96A 2bnnA-4avoA:
undetectable
2bnnB-4avoA:
undetectable		 2bnnA-4avoA:
19.42
2bnnB-4avoA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 ALA A 308
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.96A 2f80B-4avoA:
undetectable		 2f80B-4avoA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 9 ALA A 308
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 1.00A 2o4pB-4avoA:
undetectable		 2o4pB-4avoA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 10 SER A 496
HIS A 541
ALA A 536
ASN A 466
ALA A 499
 None
 1.44A 2r2vC-4avoA:
undetectable
2r2vF-4avoA:
undetectable
2r2vG-4avoA:
undetectable		 2r2vC-4avoA:
8.01
2r2vF-4avoA:
8.01
2r2vG-4avoA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 LEU A 178
ILE A 271
GLY A 313
ILE A 315
ILE A 219
 None
 0.88A 2rkgA-4avoA:
undetectable		 2rkgA-4avoA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 10 ILE A 424
LEU A 423
GLY A 421
GLY A 483
GLN A 405
 None
None
CA  A 607 ( 4.9A)
None
None
 1.20A 2wd9C-4avoA:
undetectable		 2wd9C-4avoA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 ALA A 308
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.93A 3cywB-4avoA:
undetectable		 3cywB-4avoA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 LEU A 178
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.80A 3cywB-4avoA:
undetectable		 3cywB-4avoA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 9 LEU A 178
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.91A 3d1yB-4avoA:
undetectable		 3d1yB-4avoA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 9 ALA A 308
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 1.04A 3ekvB-4avoA:
undetectable		 3ekvB-4avoA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 10 TRP A 542
PHE A 543
GLY A 498
ASN A 466
GLU A 507
 None
 1.26A 3fw1A-4avoA:
undetectable		 3fw1A-4avoA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 ALA A 308
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.93A 3jvyB-4avoA:
undetectable		 3jvyB-4avoA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 LEU A 178
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.78A 3jvyB-4avoA:
undetectable		 3jvyB-4avoA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 11 LEU A 178
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.89A 3oy4A-4avoA:
undetectable		 3oy4A-4avoA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 ALA A 308
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.96A 3tkwA-4avoA:
undetectable		 3tkwA-4avoA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		4 / 8 TYR A 397
VAL A 398
ARG A 387
ILE A 386
 None
 0.97A 4a97D-4avoA:
undetectable		 4a97D-4avoA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 LEU A 178
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.78A 4dqbA-4avoA:
undetectable		 4dqbA-4avoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 10 ALA A 308
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 1.02A 4dqcA-4avoA:
undetectable		 4dqcA-4avoA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 11 LEU A 178
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.81A 4dqeA-4avoA:
undetectable		 4dqeA-4avoA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 11 LEU A 178
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.74A 4dqhA-4avoA:
undetectable		 4dqhA-4avoA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 ALA A 308
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.97A 4hlaA-4avoA:
undetectable		 4hlaA-4avoA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 11 ALA A 308
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 1.00A 4hlaB-4avoA:
undetectable		 4hlaB-4avoA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		4 / 4 ILE A 424
SER A 362
ASP A 399
ASP A 376
 None
 1.49A 4krhB-4avoA:
undetectable		 4krhB-4avoA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		4 / 6 GLY A 147
ASP A 485
HIS A 358
ARG A 266
 None
CA  A 607 ( 4.3A)
CA  A 607 ( 4.5A)
None
 1.20A 4lajA-4avoA:
undetectable
4lajB-4avoA:
undetectable		 4lajA-4avoA:
20.77
4lajB-4avoA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 VAL A 217
LEU A 265
HIS A 200
LEU A 201
ALA A 204
 None
 0.86A 4p65B-4avoA:
undetectable
4p65D-4avoA:
undetectable
4p65I-4avoA:
undetectable
4p65J-4avoA:
undetectable		 4p65B-4avoA:
5.56
4p65D-4avoA:
5.56
4p65I-4avoA:
3.96
4p65J-4avoA:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 VAL A 217
LEU A 265
HIS A 200
LEU A 201
ALA A 204
 None
 0.78A 4p65F-4avoA:
undetectable
4p65H-4avoA:
undetectable
4p65K-4avoA:
undetectable
4p65L-4avoA:
undetectable		 4p65F-4avoA:
5.56
4p65H-4avoA:
5.56
4p65K-4avoA:
3.96
4p65L-4avoA:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 10 ALA A 308
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 1.06A 4q1wB-4avoA:
undetectable		 4q1wB-4avoA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		6 / 12 LEU A 178
ILE A 271
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 1.00A 4q1xB-4avoA:
undetectable		 4q1xB-4avoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 10 LEU A 197
GLY A 196
ASN A 153
ALA A 269
ILE A 252
 None
 1.14A 4xj7C-4avoA:
undetectable
4xj7D-4avoA:
undetectable		 4xj7C-4avoA:
22.49
4xj7D-4avoA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		4 / 4 LEU A 197
ILE A 215
HIS A 200
VAL A 217
 None
 1.21A 4xyzA-4avoA:
undetectable		 4xyzA-4avoA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 ASN A 153
HIS A 200
VAL A 155
LYS A 159
ALA A 183
 None
 1.14A 4ygfG-4avoA:
undetectable		 4ygfG-4avoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 LEU A 178
ILE A 271
GLY A 313
ILE A 315
ILE A 219
 None
 0.80A 5e5jA-4avoA:
undetectable		 5e5jA-4avoA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 LEU A 178
ILE A 271
GLY A 313
ILE A 315
ILE A 219
 None
 0.83A 5e5kA-4avoA:
undetectable		 5e5kA-4avoA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 LEU A 178
ILE A 271
GLY A 313
ILE A 315
ILE A 219
 None
 0.89A 5e5kB-4avoA:
undetectable		 5e5kB-4avoA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 9 LEU A 178
GLY A 313
ILE A 315
VAL A 217
ILE A 219
 None
 0.83A 5kr2D-4avoA:
undetectable		 5kr2D-4avoA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		4 / 5 VAL A 305
PRO A 223
GLY A 300
TYR A 301
 None
 1.39A 5x80A-4avoA:
undetectable
5x80B-4avoA:
undetectable		 5x80A-4avoA:
15.83
5x80B-4avoA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		4 / 5 PRO A 223
GLY A 300
TYR A 301
VAL A 305
 None
 1.38A 5x80C-4avoA:
undetectable
5x80D-4avoA:
undetectable		 5x80C-4avoA:
15.83
5x80D-4avoA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 11 SER A 427
ILE A 361
ASN A 363
THR A 364
GLN A 216
 None
 1.17A 5y80A-4avoA:
undetectable		 5y80A-4avoA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		4 / 6 GLY A 300
ASP A 242
GLY A 224
GLY A 237
 None
 0.75A 6ag0C-4avoA:
5.5		 6ag0C-4avoA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		5 / 12 ALA A 499
ASN A 505
GLY A 498
SER A 539
GLY A 540
 None
None
None
BGC  A 601 (-3.2A)
BGC  A 601 (-3.6A)
 1.13A 6c79A-4avoA:
undetectable		 6c79A-4avoA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4avo BETA-1,4-EXOCELLULAS
E
(Thermobifida
fusca) 		4 / 5 GLN A 216
VAL A 176
TRP A 177
THR A 191
 None
None
BGC  A 601 (-3.4A)
BGC  A 601 ( 3.8A)
 1.43A 6cduI-4avoA:
undetectable
6cduJ-4avoA:
undetectable		 6cduI-4avoA:
21.21
6cduJ-4avoA:
21.21