SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4avr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 4avr PA4485
(Pseudomonas
aeruginosa) 		4 / 6 TYR A   9
GLY A  39
PHE A  38
ARG A  56
 None
 1.31A 2a3cA-4avrA:
undetectable		 2a3cA-4avrA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 4avr PA4485
(Pseudomonas
aeruginosa) 		4 / 6 TYR A   9
GLY A  39
PHE A  38
ARG A  56
 None
 1.31A 2a3cB-4avrA:
undetectable		 2a3cB-4avrA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4avr PA4485
(Pseudomonas
aeruginosa) 		5 / 11 VAL A  44
ALA A  75
PHE A  38
LEU A  36
VAL A  42
 None
 1.42A 4eilA-4avrA:
undetectable		 4eilA-4avrA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4avr PA4485
(Pseudomonas
aeruginosa) 		5 / 11 VAL A  44
ALA A  75
PHE A  38
LEU A  36
VAL A  42
 None
 1.38A 4eilC-4avrA:
undetectable		 4eilC-4avrA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4avr PA4485
(Pseudomonas
aeruginosa) 		5 / 11 VAL A  44
ALA A  75
PHE A  38
LEU A  36
VAL A  42
 None
 1.40A 4kyaE-4avrA:
undetectable		 4kyaE-4avrA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 4avr PA4485
(Pseudomonas
aeruginosa) 		5 / 9 GLY A  80
ASN A  49
VAL A  53
SER A  52
VAL A  44
 None
 1.22A 4qd3A-4avrA:
undetectable		 4qd3A-4avrA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 4avr PA4485
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  57
ASN A  58
GLY A  61
PHE A  63
ILE A  91
 None
 1.11A 6dwnC-4avrA:
undetectable		 6dwnC-4avrA:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 4avr PA4485
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  17
GLY A  21
GLU A  22
 None
 0.62A 6fgdA-4avrA:
undetectable		 6fgdA-4avrA:
12.65