SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4aw7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 LEU A 311
SER A 254
SER A 252
ASP A 259
 None
 1.09A 1ig3A-4aw7A:
2.3
1ig3B-4aw7A:
3.7		 1ig3A-4aw7A:
20.78
1ig3B-4aw7A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASP A 259
LEU A 311
SER A 254
SER A 252
 None
 1.00A 1ig3A-4aw7A:
2.3
1ig3B-4aw7A:
3.7		 1ig3A-4aw7A:
20.78
1ig3B-4aw7A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.31A 1p6kA-4aw7A:
undetectable		 1p6kA-4aw7A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.23A 1p6kB-4aw7A:
undetectable		 1p6kB-4aw7A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.36A 1rs6A-4aw7A:
undetectable		 1rs6A-4aw7A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.29A 1rs6B-4aw7A:
undetectable		 1rs6B-4aw7A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.30A 1rs7B-4aw7A:
undetectable		 1rs7B-4aw7A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 6 HIS A 306
LEU A 404
ILE A 457
SER A 432
 None
 1.21A 1sbrA-4aw7A:
undetectable
1sbrB-4aw7A:
undetectable		 1sbrA-4aw7A:
15.70
1sbrB-4aw7A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 4 LEU A 416
PRO A 411
ILE A 463
LEU A 404
 None
IOD  A1721 ( 4.8A)
None
None
 0.99A 1ya4B-4aw7A:
undetectable		 1ya4B-4aw7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.29A 1zzqB-4aw7A:
undetectable		 1zzqB-4aw7A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.24A 1zzuB-4aw7A:
undetectable		 1zzuB-4aw7A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASP A 238
SER A 303
SER A 302
ASN A 460
 None
 1.11A 2cmlA-4aw7A:
undetectable		 2cmlA-4aw7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ASP A 238
SER A 303
SER A 302
ASN A 460
 None
 1.08A 2cmlC-4aw7A:
undetectable		 2cmlC-4aw7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 5 ARG A  75
THR A 112
LEU A 150
ALA A 200
 GLA  A1608 ( 4.9A)
None
None
None
 1.48A 2e1qD-4aw7A:
undetectable		 2e1qD-4aw7A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 11 HIS A  53
ALA A 344
SER A 343
GLY A 282
ILE A 283
 L6S  A1610 (-4.0A)
L6S  A1610 ( 4.5A)
None
None
GLA  A1608 ( 4.7A)
 1.30A 2uxpB-4aw7A:
undetectable		 2uxpB-4aw7A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_C_SPMC503_1
(SPERMIDINE SYNTHASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 12 TYR A 264
ASP A 223
SER A 486
TYR A 488
ILE A 267
 None
 1.08A 3b7pC-4aw7A:
undetectable		 3b7pC-4aw7A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CB8_A_SAMA501_0
(PYRUVATE
FORMATE-LYASE
1-ACTIVATING ENZYME)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 12 TYR A 484
ASN A 481
GLU A 313
VAL A 272
TYR A 266
 None
None
None
IOD  A1706 ( 4.3A)
None
 1.34A 3cb8A-4aw7A:
5.6		 3cb8A-4aw7A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		3 / 3 HIS A  53
PHE A 368
PHE A 369
 L6S  A1610 (-4.0A)
None
None
 0.68A 3lk0D-4aw7A:
undetectable		 3lk0D-4aw7A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.32A 3n62B-4aw7A:
undetectable		 3n62B-4aw7A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.27A 3n66B-4aw7A:
undetectable		 3n66B-4aw7A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		3 / 3 TYR A 109
ASP A  57
ASP A 327
 K  A1617 (-4.8A)
None
None
 0.59A 3ou7B-4aw7A:
undetectable		 3ou7B-4aw7A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 12 GLY A 519
ASP A 208
ILE A 553
GLY A 556
ASN A 253
 None
 1.07A 3ps9A-4aw7A:
undetectable		 3ps9A-4aw7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 12 VAL A 391
ILE A 389
GLU A 593
ILE A 478
VAL A 414
 None
 1.19A 4a97B-4aw7A:
undetectable
4a97C-4aw7A:
undetectable		 4a97B-4aw7A:
19.62
4a97C-4aw7A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 12 LEU A 407
ASN A 460
ARG A 249
ILE A 240
SER A 303
 None
 1.39A 4b3aA-4aw7A:
undetectable		 4b3aA-4aw7A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		3 / 3 ARG A 217
TYR A 237
ASN A 253
 CL  A1615 ( 4.7A)
GLA  A1608 (-4.0A)
None
 0.70A 4ffwB-4aw7A:
2.0		 4ffwB-4aw7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASP A 327
SER A  54
TRP A 331
SER A  56
 None
None
L6S  A1610 (-3.8A)
None
 1.21A 4k7gB-4aw7A:
undetectable		 4k7gB-4aw7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 12 LEU A 308
ASN A 305
GLN A 392
LEU A  44
ARG A 379
 None
 1.45A 4p6xA-4aw7A:
undetectable		 4p6xA-4aw7A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.94A 4v2yA-4aw7A:
undetectable		 4v2yA-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.95A 4v2yB-4aw7A:
undetectable		 4v2yB-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_C_EF2C151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.94A 4v2yC-4aw7A:
undetectable		 4v2yC-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.96A 4v2zA-4aw7A:
undetectable		 4v2zA-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.95A 4v2zB-4aw7A:
undetectable		 4v2zB-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.93A 4v2zC-4aw7A:
undetectable		 4v2zC-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.94A 4v30A-4aw7A:
undetectable		 4v30A-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.93A 4v30B-4aw7A:
undetectable		 4v30B-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 4 GLY A 166
VAL A 164
PHE A 176
ILE A 120
 None
 0.91A 4xv2B-4aw7A:
2.2		 4xv2B-4aw7A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		3 / 3 ALA A 263
TYR A 266
PRO A 501
 None
 0.50A 4zdyA-4aw7A:
1.6		 4zdyA-4aw7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.94A 5amhA-4aw7A:
undetectable		 5amhA-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.98A 5amiA-4aw7A:
undetectable		 5amiA-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.97A 5amiB-4aw7A:
undetectable		 5amiB-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.93A 5amjA-4aw7A:
undetectable		 5amjA-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.92A 5amjB-4aw7A:
undetectable		 5amjB-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 1.12A 5amkA-4aw7A:
undetectable		 5amkA-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.98A 5amkB-4aw7A:
undetectable		 5amkB-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 11 LEU A 172
MET A 169
PHE A 162
GLN A 121
GLY A 123
 None
 1.26A 5g6sA-4aw7A:
undetectable
5g6sG-4aw7A:
undetectable		 5g6sA-4aw7A:
21.29
5g6sG-4aw7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 11 LEU A 172
MET A 169
PHE A 162
GLN A 121
GLY A 123
 None
 1.25A 5g6sB-4aw7A:
undetectable
5g6sC-4aw7A:
undetectable		 5g6sB-4aw7A:
21.29
5g6sC-4aw7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 12 GLN A 121
GLY A 123
LEU A 172
MET A 169
PHE A 162
 None
 1.26A 5g6sB-4aw7A:
undetectable
5g6sC-4aw7A:
undetectable		 5g6sB-4aw7A:
21.29
5g6sC-4aw7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 11 LEU A 172
MET A 169
PHE A 162
GLN A 121
GLY A 123
 None
 1.25A 5g6sE-4aw7A:
undetectable
5g6sH-4aw7A:
0.2		 5g6sE-4aw7A:
21.29
5g6sH-4aw7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 10 GLN A 121
GLY A 123
LEU A 172
MET A 169
PHE A 162
 None
 1.25A 5g6sD-4aw7A:
0.0
5g6sF-4aw7A:
0.0		 5g6sD-4aw7A:
21.29
5g6sF-4aw7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 10 GLN A 121
GLY A 123
LEU A 172
MET A 169
PHE A 162
 None
 1.25A 5g6sA-4aw7A:
undetectable
5g6sG-4aw7A:
0.2		 5g6sA-4aw7A:
21.29
5g6sG-4aw7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 11 TYR A 292
ASP A 294
ARG A 361
VAL A 325
ILE A 441
 None
 1.31A 5hw8B-4aw7A:
undetectable		 5hw8B-4aw7A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.95A 5oh1A-4aw7A:
undetectable		 5oh1A-4aw7A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.98A 5oh1B-4aw7A:
undetectable		 5oh1B-4aw7A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 1.08A 5oh1C-4aw7A:
undetectable		 5oh1C-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.93A 5oh3A-4aw7A:
undetectable		 5oh3A-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASN A 317
PRO A 274
PHE A 319
TYR A  49
 None
IOD  A1704 ( 4.6A)
None
None
 0.97A 5oh3B-4aw7A:
undetectable		 5oh3B-4aw7A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 8 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.36A 5vunB-4aw7A:
undetectable		 5vunB-4aw7A:
20.03