SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4axz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4axz PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		4 / 7 THR A 185
ILE A 189
GLY A 186
PHE A 147
 None
 0.86A 2y7wC-4axzA:
undetectable		 2y7wC-4axzA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 4axz PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		3 / 3 GLU A 270
LEU A 271
ASP A 272
 None
 0.45A 3ko0A-4axzA:
1.1		 3ko0A-4axzA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 4axz PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		3 / 3 GLU A 270
LEU A 271
ASP A 272
 None
 0.39A 3ko0T-4axzA:
0.9		 3ko0T-4axzA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4axz PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		3 / 3 SER A 150
ASP A 239
ASP A 246
 None
 0.66A 3uj7A-4axzA:
undetectable		 3uj7A-4axzA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4axz PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		3 / 3 SER A 150
ASP A 239
ASP A 246
 None
 0.73A 4mwzA-4axzA:
undetectable		 4mwzA-4axzA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 4axz PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		4 / 8 ILE A  99
PHE A 102
VAL A 197
GLN A 104
 None
 1.10A 5dqyA-4axzA:
undetectable		 5dqyA-4axzA:
16.87