SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ayh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4ayh METAL-BINDING
PROTEIN YODA
(Salmonella
enterica) 		5 / 11 PHE A 154
PHE A 141
ILE A  85
GLY A  86
LEU A  32
 None
 1.06A 1z11B-4ayhA:
undetectable		 1z11B-4ayhA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 4ayh METAL-BINDING
PROTEIN YODA
(Salmonella
enterica) 		3 / 3 ASN A 160
TYR A 105
SER A 133
 None
 0.89A 2gvcB-4ayhA:
undetectable		 2gvcB-4ayhA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 4ayh METAL-BINDING
PROTEIN YODA
(Salmonella
enterica) 		3 / 3 ASN A 160
TYR A 105
SER A 133
 None
 0.91A 2gvcE-4ayhA:
undetectable		 2gvcE-4ayhA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 4ayh METAL-BINDING
PROTEIN YODA
(Salmonella
enterica) 		3 / 3 ASP A  52
ARG A  56
ARG A  75
 None
 1.02A 3k37A-4ayhA:
undetectable		 3k37A-4ayhA:
18.14