SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ayn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 4ayn FACTOR H-BINDING
PROTEIN
(Neisseria
meningitidis) 		5 / 12 LEU A 291
GLY A 242
LEU A 258
GLY A 244
TYR A 217
 None
 1.23A 1y4lA-4aynA:
undetectable		 1y4lA-4aynA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 4ayn FACTOR H-BINDING
PROTEIN
(Neisseria
meningitidis) 		5 / 10 ILE A 273
ALA A 261
ILE A 316
ILE A 299
TYR A 233
 None
 1.38A 2dm6A-4aynA:
undetectable
2dm6B-4aynA:
undetectable		 2dm6A-4aynA:
21.97
2dm6B-4aynA:
21.97