SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b0e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4b0e F1 CAPSULE-ANCHORING
PROTEIN
(Yersinia
pestis) 		5 / 10 VAL A  38
LEU A 113
LEU A  83
ALA A 119
LEU A 120
 None
 1.11A 1pxxA-4b0eA:
undetectable		 1pxxA-4b0eA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4b0e F1 CAPSULE-ANCHORING
PROTEIN
(Yersinia
pestis) 		5 / 12 VAL A  38
LEU A 113
LEU A  83
ALA A 119
LEU A 120
 None
 1.02A 3n8zB-4b0eA:
undetectable		 3n8zB-4b0eA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4b0e F1 CAPSULE-ANCHORING
PROTEIN
(Yersinia
pestis) 		4 / 7 LEU A  94
VAL A  38
TYR A  73
LEU A 111
 None
 1.11A 4b3qA-4b0eA:
undetectable		 4b3qA-4b0eA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4b0e F1 CAPSULE-ANCHORING
PROTEIN
(Yersinia
pestis) 		5 / 12 VAL A  38
LEU A 113
LEU A  83
ALA A 119
LEU A 120
 None
 1.12A 5ikqA-4b0eA:
undetectable		 5ikqA-4b0eA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4b0e F1 CAPSULE-ANCHORING
PROTEIN
(Yersinia
pestis) 		5 / 12 VAL A  38
LEU A 113
LEU A  83
ALA A 119
LEU A 120
 None
 1.12A 5ikqB-4b0eA:
undetectable		 5ikqB-4b0eA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4b0e F1 CAPSULE-ANCHORING
PROTEIN
(Yersinia
pestis) 		4 / 7 ILE A  48
LEU A 111
THR A  71
LEU A  70
 None
 0.87A 6nmpA-4b0eA:
undetectable
6nmpJ-4b0eA:
undetectable		 6nmpA-4b0eA:
13.28
6nmpJ-4b0eA:
19.67