SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b0i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GSS_B_EAAB211_1 (GLUTATHIONE S-TRANSFERASE P1-1)	4b0i	3-HYDROXYDECANOYL-[A CYL-CARRIER-PROTEIN] DEHYDRATASE (Pseudomonas aeruginosa)	4 / 7	ILE A 154 TYR A 155 THR A 146 GLY A 79	None	0.89A	3gssB-4b0iA: undetectable	3gssB-4b0iA: 24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HVC_A_HFGA1602_0 (BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE)	4b0i	3-HYDROXYDECANOYL-[A CYL-CARRIER-PROTEIN] DEHYDRATASE (Pseudomonas aeruginosa)	5 / 12	HIS A 5 GLU A 53 VAL A 45 PHE A 7 GLY A 91	None None None None KBP A1170 (-3.3A)	1.24A	4hvcA-4b0iA: undetectable	4hvcA-4b0iA: 14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB308_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	4b0i	3-HYDROXYDECANOYL-[A CYL-CARRIER-PROTEIN] DEHYDRATASE (Pseudomonas aeruginosa)	3 / 3	LEU A 64 ILE A 60 TYR A 126	None	0.55A	5uunB-4b0iA: undetectable	5uunB-4b0iA: 23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_C_ACRC607_0 (ALPHA-AMYLASE)	4b0i	3-HYDROXYDECANOYL-[A CYL-CARRIER-PROTEIN] DEHYDRATASE (Pseudomonas aeruginosa)	4 / 6	ASP A 11 GLY A 22 PRO A 23 GLY A 18	None	0.70A	6ag0C-4b0iA: undetectable	6ag0C-4b0iA: 21.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3GSS_B_EAAB211_1","GLUTATHIONE S-TRANSFERASE P1-1","4b0i","3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Pseudomonas aeruginosa",4,"ILE A 154;TYR A 155;THR A 146;GLY A  79","None","0.89A","3gssB-4b0iA:undetectable","3gssB-4b0iA:24.44"],["4HVC_A_HFGA1602_0","BIFUNCTIONAL GLUTAMATE\/PROLINE--TRNA LIGASE","4b0i","3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Pseudomonas aeruginosa",5,"HIS A   5;GLU A  53;VAL A  45;PHE A   7;GLY A  91","None;None;None;None;KBP A1170 (-3.3A)","1.24A","4hvcA-4b0iA:undetectable","4hvcA-4b0iA:14.20"],["5UUN_B_ACTB308_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","4b0i","3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Pseudomonas aeruginosa",3,"LEU A  64;ILE A  60;TYR A 126","None","0.55A","5uunB-4b0iA:undetectable","5uunB-4b0iA:23.18"],["6AG0_C_ACRC607_0","ALPHA-AMYLASE","4b0i","3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Pseudomonas aeruginosa",4,"ASP A  11;GLY A  22;PRO A  23;GLY A  18","None","0.70A","6ag0C-4b0iA:undetectable","6ag0C-4b0iA:21.74"]]