SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b1l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 4b1l LEVANASE
(Bacillus
subtilis) 		5 / 12 PHE A 548
GLY A 660
ALA A 576
GLU A 656
ALA A 585
 None
 1.16A 1sg9C-4b1lA:
undetectable		 1sg9C-4b1lA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 4b1l LEVANASE
(Bacillus
subtilis) 		5 / 12 GLY A 573
VAL A 622
ALA A 668
ASP A 665
ALA A 666
 None
 1.19A 2avdB-4b1lA:
undetectable		 2avdB-4b1lA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 4b1l LEVANASE
(Bacillus
subtilis) 		4 / 6 ASP A 643
THR A 559
GLU A 561
GLU A 631
 None
 1.46A 2dttB-4b1lA:
undetectable
2dttC-4b1lA:
undetectable		 2dttB-4b1lA:
20.12
2dttC-4b1lA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4b1l LEVANASE
(Bacillus
subtilis) 		3 / 3 GLN A 671
THR A 674
ASN A 672
 None
 0.84A 3v4tE-4b1lA:
undetectable		 3v4tE-4b1lA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 4b1l LEVANASE
(Bacillus
subtilis) 		4 / 5 TRP A 532
GLY A 575
ALA A 668
PHE A 518
 None
 1.06A 3wqwA-4b1lA:
undetectable		 3wqwA-4b1lA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 4b1l LEVANASE
(Bacillus
subtilis) 		4 / 8 GLN A 540
GLY A 541
THR A 667
THR A 531
 None
 0.89A 4k87A-4b1lA:
undetectable		 4k87A-4b1lA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 4b1l LEVANASE
(Bacillus
subtilis) 		3 / 3 ALA A 574
TRP A 664
VAL A 663
 FRU  A1678 ( 3.9A)
FRU  A1678 (-4.3A)
None
 0.44A 4w9nC-4b1lA:
undetectable		 4w9nC-4b1lA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZUD_A_OLMA1201_1
(CHIMERA PROTEIN OF
SOLUBLE CYTOCHROME
B562 AND TYPE-1
ANGIOTENSIN II
RECEPTOR)		 4b1l LEVANASE
(Bacillus
subtilis) 		5 / 9 PHE A 654
VAL A 653
SER A 652
ILE A 613
TYR A 589
 None
 1.31A 4zudA-4b1lA:
0.0		 4zudA-4b1lA:
16.05