SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 4b1m LEVANASE
(Bacillus
subtilis) 		4 / 6 ASP A 643
THR A 559
GLU A 561
GLU A 631
 None
 1.18A 2dttB-4b1mA:
undetectable
2dttC-4b1mA:
undetectable		 2dttB-4b1mA:
20.53
2dttC-4b1mA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 4b1m LEVANASE
(Bacillus
subtilis) 		3 / 3 GLU A 561
ASP A 563
ASP A 643
 None
 0.40A 3jb2A-4b1mA:
undetectable		 3jb2A-4b1mA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4b1m LEVANASE
(Bacillus
subtilis) 		3 / 3 GLN A 671
THR A 674
ASN A 672
 None
 0.82A 3v4tE-4b1mA:
undetectable		 3v4tE-4b1mA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZUD_A_OLMA1201_1
(CHIMERA PROTEIN OF
SOLUBLE CYTOCHROME
B562 AND TYPE-1
ANGIOTENSIN II
RECEPTOR)		 4b1m LEVANASE
(Bacillus
subtilis) 		5 / 9 PHE A 654
VAL A 653
SER A 652
ILE A 613
TYR A 589
 None
 1.29A 4zudA-4b1mA:
0.0		 4zudA-4b1mA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 4b1m LEVANASE
(Bacillus
subtilis) 		4 / 5 GLY A 573
ASP A 665
ARG A 572
GLN A 540
 None
 1.30A 5zrfB-4b1mA:
undetectable		 5zrfB-4b1mA:
13.22