SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b2f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 4b2f PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		3 / 3 PHE A 187
LEU A 181
SER A 273
 None
 0.90A 1e7aA-4b2fA:
undetectable		 1e7aA-4b2fA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4b2f PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		3 / 3 SER A 150
ASP A 239
ASP A 246
 None
 0.72A 3uj7A-4b2fA:
undetectable		 3uj7A-4b2fA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 4b2f PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		4 / 5 PHE A 147
THR A 163
PHE A 126
ILE A 158
 None
 1.20A 4jx1E-4b2fA:
undetectable		 4jx1E-4b2fA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4b2f PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		3 / 3 SER A 150
ASP A 239
ASP A 246
 None
 0.82A 4mwzA-4b2fA:
undetectable		 4mwzA-4b2fA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 4b2f PUTATIVE ANTIGEN P35
(Borreliella
burgdorferi) 		4 / 8 LEU A 178
GLU A 244
LEU A 259
ILE A 164
 None
 0.83A 5mzjA-4b2fA:
2.9		 5mzjA-4b2fA:
19.19