SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b2z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 4b2z OXYSTEROL-BINDING
PROTEIN HOMOLOG 6
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 339
THR A  71
LEU A  69
LEU A 128
 None
None
P5S  A1436 (-3.6A)
None
 0.81A 1gtiA-4b2zA:
undetectable		 1gtiA-4b2zA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 4b2z OXYSTEROL-BINDING
PROTEIN HOMOLOG 6
(Saccharomyces
cerevisiae) 		4 / 6 LYS A 333
LYS A 334
ASP A 337
ALA A 338
 None
 0.36A 1iwhA-4b2zA:
undetectable		 1iwhA-4b2zA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)		 4b2z OXYSTEROL-BINDING
PROTEIN HOMOLOG 6
(Saccharomyces
cerevisiae) 		4 / 4 GLN A 403
GLU A 401
ILE A 404
PRO A 169
 None
 1.44A 2fcnA-4b2zA:
undetectable		 2fcnA-4b2zA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 4b2z OXYSTEROL-BINDING
PROTEIN HOMOLOG 6
(Saccharomyces
cerevisiae) 		5 / 12 THR A 218
ILE A 251
ASP A 250
GLN A 248
ALA A 249
 None
 1.25A 3ddyA-4b2zA:
undetectable		 3ddyA-4b2zA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 4b2z OXYSTEROL-BINDING
PROTEIN HOMOLOG 6
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 221
PRO A 220
MET A 193
PHE A 253
 None
 1.47A 4v2zB-4b2zA:
undetectable		 4v2zB-4b2zA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 4b2z OXYSTEROL-BINDING
PROTEIN HOMOLOG 6
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 221
PRO A 220
MET A 193
PHE A 253
 None
 1.49A 4v30B-4b2zA:
undetectable		 4v30B-4b2zA:
13.51