SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		3 / 3 THR A 137
PRO A 134
THR A 135
 None
 0.91A 1dscC-4b3vA:
undetectable		 1dscC-4b3vA:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		5 / 9 PHE A 102
TYR A 109
THR A  55
GLY A  94
VAL A 138
 None
None
PEG  A1449 ( 4.2A)
PEG  A1449 ( 3.4A)
CA  A1451 ( 4.6A)
 1.29A 1dz8A-4b3vA:
undetectable		 1dz8A-4b3vA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		5 / 9 PHE A 102
TYR A 109
THR A  55
GLY A  94
VAL A 138
 None
None
PEG  A1449 ( 4.2A)
PEG  A1449 ( 3.4A)
CA  A1451 ( 4.6A)
 1.25A 1dz8B-4b3vA:
undetectable		 1dz8B-4b3vA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		5 / 9 PHE A 102
TYR A 109
THR A  55
GLY A  94
VAL A 138
 None
None
PEG  A1449 ( 4.2A)
PEG  A1449 ( 3.4A)
CA  A1451 ( 4.6A)
 1.26A 1dz9B-4b3vA:
undetectable		 1dz9B-4b3vA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		5 / 11 LEU A 257
LEU A  62
LEU A 289
VAL A  87
ILE A  50
 None
 0.97A 1ee2A-4b3vA:
undetectable		 1ee2A-4b3vA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		5 / 11 LEU A 257
LEU A  62
LEU A 289
VAL A  87
ILE A  50
 None
 1.02A 1ee2B-4b3vA:
undetectable		 1ee2B-4b3vA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		3 / 3 ALA A  24
VAL A  26
TRP A 167
 None
 0.87A 1w5uC-4b3vA:
undetectable
1w5uD-4b3vA:
undetectable		 1w5uC-4b3vA:
9.56
1w5uD-4b3vA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		3 / 3 ALA A  24
VAL A  26
TRP A 167
 None
 0.84A 3l8lA-4b3vA:
undetectable
3l8lB-4b3vA:
undetectable		 3l8lA-4b3vA:
9.56
3l8lB-4b3vA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		5 / 12 GLY A 288
ILE A  74
ALA A  48
PHE A 142
ALA A 143
 None
 1.01A 3sudB-4b3vA:
undetectable		 3sudB-4b3vA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		5 / 12 GLY A 288
ILE A  74
ALA A  48
PHE A 142
ALA A 143
 None
 1.02A 3sudC-4b3vA:
undetectable		 3sudC-4b3vA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		5 / 12 LEU A 370
VAL A 377
VAL A 346
LEU A 391
THR A 393
 None
 0.97A 4m2vA-4b3vA:
undetectable		 4m2vA-4b3vA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		4 / 7 THR A   5
LEU A 324
THR A  15
THR A 179
 None
 1.13A 4mbsA-4b3vA:
undetectable		 4mbsA-4b3vA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		4 / 7 THR A  15
LEU A   7
THR A   5
THR A 179
 None
 1.15A 4mbsA-4b3vA:
undetectable		 4mbsA-4b3vA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		4 / 5 PHE A 102
PHE A 123
LEU A 257
PRO A 278
 None
 1.34A 4o8zA-4b3vA:
undetectable		 4o8zA-4b3vA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		3 / 3 LYS A 153
HIS A 152
HIS A 150
 None
 1.48A 5oexB-4b3vA:
undetectable		 5oexB-4b3vA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		5 / 12 GLY A  61
GLY A  47
GLY A  63
THR A  46
VAL A 276
 None
 1.04A 5wz1C-4b3vA:
undetectable		 5wz1C-4b3vA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 4b3v E1 ENVELOPE
GLYCOPROTEIN
(Rubella
virus) 		5 / 12 GLY A  61
GLY A  47
GLY A  63
THR A  46
VAL A 276
 None
 1.04A 5wz1E-4b3vA:
undetectable		 5wz1E-4b3vA:
18.53