SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b4y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 4b4y NEUROGLOBIN
(Symsagittifera
roscoffensis) 		5 / 9 TYR A  28
ILE A 120
LEU A 116
ILE A  75
GLY A  76
 None
None
HEM  A1155 ( 4.3A)
HEM  A1155 ( 3.9A)
None
 1.29A 5ifuB-4b4yA:
undetectable		 5ifuB-4b4yA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 4b4y NEUROGLOBIN
(Symsagittifera
roscoffensis) 		4 / 5 LEU A  86
LEU A  83
MET A 151
GLN A   8
 None
 1.09A 5uc3A-4b4yA:
undetectable		 5uc3A-4b4yA:
17.31