SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b52'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 7 GLY A 155
ALA A 160
THR A 142
SER A 162
 None
None
None
ZN  A 401 ( 4.9A)
 0.88A 1c9sT-4b52A:
undetectable
1c9sU-4b52A:
undetectable		 1c9sT-4b52A:
12.83
1c9sU-4b52A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 6 GLN A 170
TYR A  69
VAL A 133
GLY A 128
 CA  A 402 (-2.9A)
None
None
None
 1.04A 1ekjC-4b52A:
undetectable
1ekjD-4b52A:
undetectable		 1ekjC-4b52A:
21.11
1ekjD-4b52A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3007_0
(BETA-CARBONIC
ANHYDRASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 6 ASP A 131
VAL A 133
GLN A 170
TYR A  69
 CA  A 402 (-2.9A)
None
CA  A 402 (-2.9A)
None
 1.19A 1ekjC-4b52A:
undetectable
1ekjD-4b52A:
undetectable		 1ekjC-4b52A:
21.11
1ekjD-4b52A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 7 GLY A 155
ALA A 160
THR A 142
SER A 162
 None
None
None
ZN  A 401 ( 4.9A)
 0.82A 1gtfL-4b52A:
undetectable
1gtfM-4b52A:
undetectable		 1gtfL-4b52A:
12.83
1gtfM-4b52A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 GLY A 155
ALA A 160
THR A 142
SER A 162
 None
None
None
ZN  A 401 ( 4.9A)
 0.80A 1gtfN-4b52A:
undetectable
1gtfO-4b52A:
undetectable		 1gtfN-4b52A:
12.83
1gtfO-4b52A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 4 ASP A 163
HIS A 135
ARG A 191
GLU A 159
 None
ZN  A 401 ( 3.2A)
RDF  A 501 (-2.7A)
ZN  A 401 ( 1.9A)
 0.97A 1lqtA-4b52A:
undetectable		 1lqtA-4b52A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 PHE A 269
TYR A 205
LEU A 208
GLY A 217
 None
 0.86A 1rmtC-4b52A:
undetectable		 1rmtC-4b52A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 8 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.19A 1v7zA-4b52A:
undetectable		 1v7zA-4b52A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 8 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.19A 1v7zB-4b52A:
undetectable		 1v7zB-4b52A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 8 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.20A 1v7zC-4b52A:
undetectable		 1v7zC-4b52A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 8 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.20A 1v7zD-4b52A:
undetectable		 1v7zD-4b52A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 8 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.19A 1v7zE-4b52A:
undetectable		 1v7zE-4b52A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 8 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.20A 1v7zF-4b52A:
undetectable		 1v7zF-4b52A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 7 ASN A 158
TYR A 150
ASN A 215
HIS A 219
 None
RDF  A 501 ( 4.7A)
None
RDF  A 501 (-3.6A)
 1.41A 1wu8A-4b52A:
undetectable
1wu8C-4b52A:
undetectable		 1wu8A-4b52A:
21.04
1wu8C-4b52A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 12 ALA A 106
HIS A 135
GLU A 136
HIS A 139
GLU A 159
 RDF  A 501 (-4.7A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-2.5A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 1.9A)
 0.42A 2c6nA-4b52A:
5.4		 2c6nA-4b52A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 ASP A  60
LEU A  51
HIS A  98
SER A  41
 None
 1.07A 2q0iA-4b52A:
undetectable		 2q0iA-4b52A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 12 ALA A  79
THR A 260
PHE A 161
ILE A 165
ASP A 168
 None
 1.34A 2v95A-4b52A:
undetectable		 2v95A-4b52A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 12 PHE A 238
ALA A 156
ALA A 272
VAL A 303
GLY A 302
 None
 1.11A 2ve3B-4b52A:
undetectable		 2ve3B-4b52A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 12 PHE A 238
ALA A 160
ALA A 272
VAL A 303
GLY A 302
 None
 1.19A 2ve3B-4b52A:
undetectable		 2ve3B-4b52A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 12 ILE A 180
TYR A 229
PHE A 298
ALA A 258
THR A 260
 None
 1.39A 2x2nD-4b52A:
undetectable		 2x2nD-4b52A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 8 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.16A 3a6jA-4b52A:
undetectable		 3a6jA-4b52A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 7 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.14A 3a6jB-4b52A:
undetectable		 3a6jB-4b52A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 8 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.15A 3a6jC-4b52A:
undetectable		 3a6jC-4b52A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 8 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.16A 3a6jE-4b52A:
undetectable		 3a6jE-4b52A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 8 GLU A 159
HIS A 135
HIS A 219
HIS A 139
GLU A 136
 ZN  A 401 ( 1.9A)
ZN  A 401 ( 3.2A)
RDF  A 501 (-3.6A)
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
 1.15A 3a6jF-4b52A:
undetectable		 3a6jF-4b52A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 LEU A 157
PHE A 259
ALA A 275
ALA A 258
 None
 0.91A 3ax9B-4b52A:
undetectable		 3ax9B-4b52A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 12 GLY A 217
GLY A 211
GLU A 153
TYR A 151
ASN A 215
 None
 1.40A 3t7sC-4b52A:
undetectable		 3t7sC-4b52A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 6 HIS A 139
GLU A 159
ASP A 163
SER A 222
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 1.9A)
None
None
 0.87A 4apjA-4b52A:
6.4
4apjP-4b52A:
undetectable		 4apjA-4b52A:
19.86
4apjP-4b52A:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 10 ALA A 274
LEU A 263
ALA A 258
SER A 297
ALA A 294
 None
 1.13A 4zbrA-4b52A:
2.1		 4zbrA-4b52A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 GLY A 211
ILE A 224
SER A 222
GLY A 217
 None
 0.83A 5alcL-4b52A:
undetectable		 5alcL-4b52A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 THR A 142
SER A 162
GLY A 155
ALA A 160
 None
ZN  A 401 ( 4.9A)
None
None
 0.81A 5eevL-4b52A:
undetectable
5eevV-4b52A:
undetectable		 5eevL-4b52A:
12.83
5eevV-4b52A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 THR A 142
SER A 162
GLY A 155
ALA A 160
 None
ZN  A 401 ( 4.9A)
None
None
 0.81A 5eewL-4b52A:
undetectable
5eewV-4b52A:
undetectable		 5eewL-4b52A:
12.83
5eewV-4b52A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 THR A 142
SER A 162
GLY A 155
ALA A 160
 None
ZN  A 401 ( 4.9A)
None
None
 0.81A 5eezL-4b52A:
undetectable
5eezV-4b52A:
undetectable		 5eezL-4b52A:
12.83
5eezV-4b52A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 THR A 142
SER A 162
GLY A 155
ALA A 160
 None
ZN  A 401 ( 4.9A)
None
None
 0.81A 5ef1L-4b52A:
undetectable
5ef1V-4b52A:
undetectable		 5ef1L-4b52A:
12.83
5ef1V-4b52A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 THR A 142
SER A 162
GLY A 155
ALA A 160
 None
ZN  A 401 ( 4.9A)
None
None
 0.81A 5ef2L-4b52A:
undetectable
5ef2V-4b52A:
undetectable		 5ef2L-4b52A:
12.83
5ef2V-4b52A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 8 THR A 142
SER A 162
GLY A 155
ALA A 160
 None
ZN  A 401 ( 4.9A)
None
None
 0.81A 5ef3L-4b52A:
undetectable
5ef3V-4b52A:
undetectable		 5ef3L-4b52A:
12.83
5ef3V-4b52A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 4 SER A 127
ALA A  66
GLN A 112
THR A  37
 None
 1.24A 5n0rA-4b52A:
undetectable		 5n0rA-4b52A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 4 SER A 127
ALA A  66
GLN A 112
THR A  37
 None
 1.24A 5n0sA-4b52A:
undetectable		 5n0sA-4b52A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 5 SER A 127
ALA A  66
GLN A 112
THR A  37
 None
 1.23A 5n0tA-4b52A:
undetectable		 5n0tA-4b52A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 4 SER A 127
ALA A  66
GLN A 112
THR A  37
 None
 1.26A 5n0wA-4b52A:
undetectable		 5n0wA-4b52A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 5 SER A 127
ALA A  66
GLN A 112
THR A  37
 None
 1.29A 5n0wB-4b52A:
undetectable		 5n0wB-4b52A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 4 SER A 127
ALA A  66
GLN A 112
THR A  37
 None
 1.26A 5n0xA-4b52A:
undetectable		 5n0xA-4b52A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 5 SER A 127
ALA A  66
GLN A 112
THR A  37
 None
 1.28A 5n4iA-4b52A:
undetectable		 5n4iA-4b52A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		6 / 12 GLY A 128
GLY A 166
GLY A 134
HIS A 139
GLU A 136
ASP A 131
 None
None
None
ZN  A 401 ( 3.3A)
RDF  A 501 (-2.5A)
CA  A 402 (-2.9A)
 1.26A 5njvC-4b52A:
undetectable		 5njvC-4b52A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 7 ASP A 129
GLY A 128
ASP A 131
ASP A 179
 CA  A 402 (-2.0A)
None
CA  A 402 (-2.9A)
CA  A 402 (-3.7A)
 1.06A 5nnwD-4b52A:
undetectable		 5nnwD-4b52A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 7 ASP A 129
GLY A 128
ASP A 131
ASP A 179
 CA  A 402 (-2.0A)
None
CA  A 402 (-2.9A)
CA  A 402 (-3.7A)
 1.09A 5no9D-4b52A:
undetectable		 5no9D-4b52A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		5 / 10 VAL A 133
GLY A 134
ILE A  86
THR A  73
ALA A  70
 None
 1.02A 5vm8B-4b52A:
undetectable		 5vm8B-4b52A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 7 LEU A   9
ASP A 179
ASP A 178
GLN A 170
 None
CA  A 402 (-3.7A)
CA  A 402 (-2.9A)
CA  A 402 (-2.9A)
 1.22A 6g31D-4b52A:
undetectable		 6g31D-4b52A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4b52 BACILLOLYSIN
(Paenibacillus
polymyxa) 		4 / 6 LEU A   9
ASP A 179
ASP A 178
GLN A 170
 None
CA  A 402 (-3.7A)
CA  A 402 (-2.9A)
CA  A 402 (-2.9A)
 1.24A 6g31J-4b52A:
undetectable		 6g31J-4b52A:
13.55