SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b60'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4b60 FIBRONECTIN-BINDING
PROTEIN A
(Staphylococcus
aureus) 		4 / 8 VAL A 380
THR A 381
VAL A 397
ILE A 399
 None
 0.97A 2qbmA-4b60A:
undetectable		 2qbmA-4b60A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4b60 FIBRONECTIN-BINDING
PROTEIN A
(Staphylococcus
aureus) 		4 / 5 VAL A 251
LEU A 247
ILE A 208
ALA A 225
 None
 0.93A 3n8yB-4b60A:
undetectable		 3n8yB-4b60A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4b60 FIBRONECTIN-BINDING
PROTEIN A
(Staphylococcus
aureus) 		4 / 8 THR A 381
TYR A 457
TYR A 442
LEU A 348
 None
 1.12A 3wipG-4b60A:
3.1
3wipH-4b60A:
3.0		 3wipG-4b60A:
21.90
3wipH-4b60A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4b60 FIBRONECTIN-BINDING
PROTEIN A
(Staphylococcus
aureus) 		4 / 8 LEU A 348
THR A 381
TYR A 457
TYR A 442
 None
 1.05A 3wipF-4b60A:
2.1
3wipJ-4b60A:
undetectable		 3wipF-4b60A:
21.90
3wipJ-4b60A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQE_B_DXCB1079_0
(PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD)		 4b60 FIBRONECTIN-BINDING
PROTEIN A
(Staphylococcus
aureus) 		5 / 11 LYS A 232
GLN A 328
THR A 323
LEU A 324
TYR A 229
 None
 1.46A 3zqeA-4b60A:
undetectable
3zqeB-4b60A:
undetectable		 3zqeA-4b60A:
22.45
3zqeB-4b60A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 4b60 FIBRONECTIN-BINDING
PROTEIN A
(Staphylococcus
aureus) 		4 / 4 VAL A 217
ILE A 320
ASN A 252
VAL A 312
 None
 1.21A 5ajqA-4b60A:
undetectable		 5ajqA-4b60A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4b60 FIBRONECTIN-BINDING
PROTEIN A
(Staphylococcus
aureus) 		4 / 8 ILE A 265
PHE A 287
ALA A 299
PHE A 233
 None
 0.91A 5m0oC-4b60A:
undetectable		 5m0oC-4b60A:
22.45