SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_B_ADNB1237_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	4b6v	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 (Mus musculus)	5 / 11	ARG A 95 GLY A 146 GLU A 93 SER A 148 ILE A 144	None	1.30A	1odiB-4b6vA: undetectable	1odiB-4b6vA: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_B_DESB459_2 (ESTROGEN-RELATED RECEPTOR GAMMA)	4b6v	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 (Mus musculus)	3 / 3	LEU A 180 HIS A 183 ILE A 184	None	0.63A	1s9pB-4b6vA: undetectable	1s9pB-4b6vA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOD_A_HQEA1173_1 (FMN-BINDING PROTEIN)	4b6v	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 (Mus musculus)	4 / 7	TRP A 161 ARG A 95 HIS A 194 HIS A 88	None	1.29A	3zodA-4b6vA: undetectable	3zodA-4b6vA: 22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JWA_A_ACTA609_0 (NADH DEHYDROGENASE, PUTATIVE)	4b6v	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 (Mus musculus)	3 / 3	VAL A 78 SER A 119 TRP A 122	None	0.97A	5jwaA-4b6vA: undetectable	5jwaA-4b6vA: 14.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ODI_B_ADNB1237_1","PURINE NUCLEOSIDE PHOSPHORYLASE","4b6v","EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3","Mus musculus",5,"ARG A  95;GLY A 146;GLU A  93;SER A 148;ILE A 144","None","1.30A","1odiB-4b6vA:undetectable","1odiB-4b6vA:21.19"],["1S9P_B_DESB459_2","ESTROGEN-RELATED RECEPTOR GAMMA","4b6v","EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3","Mus musculus",3,"LEU A 180;HIS A 183;ILE A 184","None","0.63A","1s9pB-4b6vA:undetectable","1s9pB-4b6vA:21.95"],["3ZOD_A_HQEA1173_1","FMN-BINDING PROTEIN","4b6v","EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3","Mus musculus",4,"TRP A 161;ARG A  95;HIS A 194;HIS A  88","None","1.29A","3zodA-4b6vA:undetectable","3zodA-4b6vA:22.62"],["5JWA_A_ACTA609_0","NADH DEHYDROGENASE, PUTATIVE","4b6v","EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3","Mus musculus",3,"VAL A  78;SER A 119;TRP A 122","None","0.97A","5jwaA-4b6vA:undetectable","5jwaA-4b6vA:14.59"]]