SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 5 ASP A 179
ASP A 173
LEU A 166
ALA A 174
 None
 1.10A 1nh8A-4b7gA:
undetectable		 1nh8A-4b7gA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 8 ILE A 350
LEU A 346
PHE A 215
GLY A 211
 None
 1.02A 1os6A-4b7gA:
undetectable		 1os6A-4b7gA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A 465
ILE A 459
GLY A 458
HIS A 189
GLN A 456
 None
NDP  A1518 ( 4.3A)
None
NDP  A1518 (-3.8A)
NDP  A1518 (-4.7A)
 1.48A 1s9aB-4b7gA:
undetectable		 1s9aB-4b7gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U65_A_CP0A1000_1
(ACETYLCHOLINESTERASE)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		5 / 11 GLN A 163
TYR A 495
TRP A 178
ASP A 242
HIS A 189
 None
None
None
None
NDP  A1518 (-3.8A)
 1.27A 1u65A-4b7gA:
undetectable		 1u65A-4b7gA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 5 VAL A 191
THR A 192
VAL A 499
TRP A 496
 None
 1.03A 2p2fA-4b7gA:
undetectable		 2p2fA-4b7gA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 5 ARG A 506
ALA A 474
ASP A 475
GLU A 471
 None
 1.18A 2xrzA-4b7gA:
undetectable		 2xrzA-4b7gA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 7 TYR A 511
GLY A 504
VAL A 492
ASP A 500
 None
 0.94A 2y05A-4b7gA:
undetectable
2y05B-4b7gA:
undetectable		 2y05A-4b7gA:
20.87
2y05B-4b7gA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 7 PHE A 159
LEU A 194
VAL A 124
THR A 110
 None
 0.97A 2zaxA-4b7gA:
undetectable		 2zaxA-4b7gA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 5 TYR A 229
ILE A 140
LEU A  81
LEU A  95
 None
 1.14A 2zb7A-4b7gA:
undetectable		 2zb7A-4b7gA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 7 PHE A 159
LEU A 194
VAL A 124
THR A 110
 None
 0.95A 3fwgB-4b7gA:
undetectable		 3fwgB-4b7gA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 7 PHE A 159
LEU A 194
VAL A 124
THR A 110
 None
 0.98A 3fwiA-4b7gA:
undetectable		 3fwiA-4b7gA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 8 ILE A 350
LEU A 346
PHE A 215
GLY A 211
 None
 0.97A 3selX-4b7gA:
undetectable		 3selX-4b7gA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 6 ILE A 350
LEU A 346
PHE A 215
GLY A 211
 None
 0.93A 3sj1X-4b7gA:
undetectable		 3sj1X-4b7gA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 5 ASP A 293
GLU A 186
TYR A 445
ASP A 343
 None
 1.25A 3w9tD-4b7gA:
undetectable		 3w9tD-4b7gA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 7 ILE A 350
LEU A 346
PHE A 215
GLY A 211
 None
 1.00A 4hc3A-4b7gA:
undetectable		 4hc3A-4b7gA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 6 GLY A 142
ASP A 139
PRO A 331
ARG A 349
 HEM  A3000 (-3.9A)
None
None
HEM  A3000 (-3.5A)
 1.20A 4lajA-4b7gA:
undetectable
4lajB-4b7gA:
undetectable		 4lajA-4b7gA:
20.75
4lajB-4b7gA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 6 GLY A 211
ASP A 139
PRO A 331
ARG A 349
 None
None
None
HEM  A3000 (-3.5A)
 1.06A 4lajA-4b7gA:
undetectable
4lajB-4b7gA:
undetectable		 4lajA-4b7gA:
20.75
4lajB-4b7gA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 7 LEU A 503
GLU A 469
LYS A 470
LEU A 473
 None
NDP  A1518 (-3.5A)
None
None
 0.72A 4wg0L-4b7gA:
undetectable
4wg0M-4b7gA:
undetectable		 4wg0L-4b7gA:
2.33
4wg0M-4b7gA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		5 / 12 ALA A  93
LEU A 129
PHE A 108
PHE A 127
PHE A 131
 None
 1.21A 5fsaA-4b7gA:
undetectable		 5fsaA-4b7gA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 8 GLY A 136
GLN A 357
TYR A 365
ASP A 139
 None
HEM  A3000 (-3.7A)
None
None
 0.99A 5vlmB-4b7gA:
undetectable		 5vlmB-4b7gA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 7 GLY A 136
GLN A 357
TYR A 365
ASP A 139
 None
HEM  A3000 (-3.7A)
None
None
 0.85A 5vlmE-4b7gA:
2.8		 5vlmE-4b7gA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 7 GLY A 136
GLN A 357
TYR A 365
ASP A 139
 None
HEM  A3000 (-3.7A)
None
None
 0.94A 5vlmG-4b7gA:
undetectable		 5vlmG-4b7gA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 4b7g CATALASE
(Corynebacterium
glutamicum) 		3 / 3 TYR A 388
PRO A 369
LEU A 368
 None
 0.84A 6beoA-4b7gA:
undetectable		 6beoA-4b7gA:
2.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A 140
SER A 212
LEU A 104
PHE A 311
PHE A 108
 None
HEM  A3000 (-3.5A)
None
None
None
 1.37A 6dwnB-4b7gA:
undetectable		 6dwnB-4b7gA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		5 / 12 ASP A 123
VAL A 111
SER A 162
PHE A 149
PHE A 159
 None
 1.46A 6h7mB-4b7gA:
undetectable		 6h7mB-4b7gA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4b7g CATALASE
(Corynebacterium
glutamicum) 		4 / 8 TYR A 132
VAL A 370
ASN A 371
ASN A 333
 None
 1.11A 6hzpA-4b7gA:
undetectable		 6hzpA-4b7gA:
19.89