SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b7j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ASN A 295
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 0.68A 1a4gA-4b7jA:
53.0		 1a4gA-4b7jA:
31.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.46A 1a4gA-4b7jA:
53.0		 1a4gA-4b7jA:
31.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.66A 1a4gB-4b7jA:
53.0		 1a4gB-4b7jA:
31.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 ARG A 152
ASN A 295
ARG A 368
ARG A 118
 G39  A1470 (-3.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-3.1A)
 1.40A 1f9gA-4b7jA:
undetectable		 1f9gA-4b7jA:
19.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 179
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
None
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.42A 1l7fA-4b7jA:
64.5		 1l7fA-4b7jA:
40.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ARG A 152
ARG A 368
 G39  A1470 (-3.1A)
G39  A1470 (-3.9A)
G39  A1470 (-3.0A)
 0.20A 1l7fA-4b7jA:
64.5		 1l7fA-4b7jA:
40.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7G_A_BCZA801_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 179
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
TYR A 402
 None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.28A 1l7gA-4b7jA:
64.4		 1l7gA-4b7jA:
40.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7H_A_BCZA801_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 179
ARG A 225
GLU A 228
GLU A 277
GLU A 278
TYR A 402
 G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
None
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-4.5A)
 0.44A 1l7hA-4b7jA:
64.4		 1l7hA-4b7jA:
40.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ARG A 152
ARG A 368
 G39  A1470 (-3.1A)
G39  A1470 (-3.9A)
G39  A1470 (-3.0A)
 0.21A 1l7hA-4b7jA:
64.4		 1l7hA-4b7jA:
40.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 152
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.9A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.60A 1nncA-4b7jA:
64.0		 1nncA-4b7jA:
40.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		6 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 1.14A 1nncA-4b7jA:
64.0		 1nncA-4b7jA:
40.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		6 / 12 LEU A 426
ASP A 459
GLY A 460
ALA A 461
GLY A 109
ILE A 108
 None
 1.24A 1rl8B-4b7jA:
undetectable		 1rl8B-4b7jA:
11.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.65A 2cmlA-4b7jA:
64.2		 2cmlA-4b7jA:
38.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.47A 2cmlA-4b7jA:
64.2		 2cmlA-4b7jA:
38.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 179
 None
G39  A1470 (-3.9A)
None
None
 0.23A 2cmlA-4b7jA:
64.2		 2cmlA-4b7jA:
38.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.58A 2cmlB-4b7jA:
64.1		 2cmlB-4b7jA:
38.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2477_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 179
 None
G39  A1470 (-3.9A)
None
None
 0.27A 2cmlB-4b7jA:
64.1		 2cmlB-4b7jA:
38.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 SER A 364
SER A 366
SER A 367
ASN A 369
 None
 1.11A 2cmlB-4b7jA:
64.1		 2cmlB-4b7jA:
38.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.63A 2cmlC-4b7jA:
64.1		 2cmlC-4b7jA:
38.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.49A 2cmlC-4b7jA:
64.1		 2cmlC-4b7jA:
38.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 179
 None
G39  A1470 (-3.9A)
None
None
 0.31A 2cmlC-4b7jA:
64.1		 2cmlC-4b7jA:
38.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.61A 2cmlD-4b7jA:
64.1		 2cmlD-4b7jA:
38.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4477_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 179
 None
G39  A1470 (-3.9A)
None
None
 0.23A 2cmlD-4b7jA:
64.1		 2cmlD-4b7jA:
38.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 118
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.44A 2f0zA-4b7jA:
21.4		 2f0zA-4b7jA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 156
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 1.11A 2f0zA-4b7jA:
21.4		 2f0zA-4b7jA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F10_A_BCZA382_0
(SIALIDASE 2)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 118
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.47A 2f10A-4b7jA:
9.5		 2f10A-4b7jA:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 152
ARG A 156
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.9A)
None
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.67A 2htqA-4b7jA:
67.2		 2htqA-4b7jA:
53.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-4.0A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 1.13A 2htqA-4b7jA:
67.2		 2htqA-4b7jA:
53.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
TRP A 179
SER A 180
ARG A 225
GLU A 277
ARG A 293
TYR A 402
 G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
None
G39  A1470 ( 4.5A)
G39  A1470 (-4.4A)
G39  A1470 (-3.7A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.44A 2htuA-4b7jA:
68.4		 2htuA-4b7jA:
53.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 118
ASP A 151
GLU A 228
ARG A 368
 G39  A1470 (-3.1A)
G39  A1470 (-3.7A)
None
G39  A1470 (-3.0A)
 0.33A 2htuA-4b7jA:
68.4		 2htuA-4b7jA:
53.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
SER A 247
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 ( 4.3A)
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.55A 3b7eA-4b7jA:
74.5		 3b7eA-4b7jA:
82.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 228
SER A 247
ARG A 293
ASN A 295
TYR A 402
 None
G39  A1470 ( 4.3A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 1.26A 3b7eA-4b7jA:
74.5		 3b7eA-4b7jA:
82.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
SER A 247
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 ( 4.3A)
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.55A 3b7eB-4b7jA:
74.4		 3b7eB-4b7jA:
82.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
ARG A 152
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.9A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.63A 3ckzA-4b7jA:
74.2		 3ckzA-4b7jA:
90.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ARG A 152
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.9A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.39A 3ckzA-4b7jA:
74.2		 3ckzA-4b7jA:
90.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		6 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 1.06A 3ckzA-4b7jA:
74.2		 3ckzA-4b7jA:
90.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 6 ASP A 151
ARG A 156
TRP A 179
ARG A 225
SER A 247
 G39  A1470 (-3.7A)
None
None
G39  A1470 (-4.4A)
G39  A1470 ( 4.3A)
 0.74A 3ckzA-4b7jA:
74.2		 3ckzA-4b7jA:
90.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		6 / 10 LEU A 426
ASP A 459
GLY A 460
ALA A 461
GLY A 109
ILE A 108
 None
 1.27A 3ekpD-4b7jA:
undetectable		 3ekpD-4b7jA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		6 / 9 LEU A 426
ASP A 459
GLY A 460
ALA A 461
GLY A 109
ILE A 108
 None
 1.25A 3ektA-4b7jA:
undetectable		 3ektA-4b7jA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 ILE A 389
LYS A 363
PHE A 371
PHE A 422
 None
 1.27A 3elzB-4b7jA:
undetectable		 3elzB-4b7jA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 GLU A 228
GLU A 278
TRP A 423
 None
G39  A1470 (-4.2A)
None
 0.95A 3hrdA-4b7jA:
undetectable
3hrdE-4b7jA:
undetectable
3hrdF-4b7jA:
undetectable		 3hrdA-4b7jA:
19.60
3hrdE-4b7jA:
19.60
3hrdF-4b7jA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_A_BCZA468_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 156
TRP A 179
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
None
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.44A 3k37A-4b7jA:
53.2		 3k37A-4b7jA:
33.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ASP A 151
ARG A 152
ARG A 368
 G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
G39  A1470 (-3.0A)
 0.24A 3k37A-4b7jA:
53.2		 3k37A-4b7jA:
33.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 118
ASP A 151
ARG A 156
TRP A 179
ARG A 223
 G39  A1470 (-3.1A)
G39  A1470 (-3.7A)
None
None
G39  A1470 (-4.0A)
 1.36A 3k37B-4b7jA:
53.1		 3k37B-4b7jA:
33.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 179
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ARG A 368
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
None
None
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
 0.42A 3k37B-4b7jA:
53.1		 3k37B-4b7jA:
33.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
GLU A 277
TYR A 402
 G39  A1470 (-3.9A)
G39  A1470 (-3.7A)
G39  A1470 (-4.5A)
 0.77A 3k37B-4b7jA:
53.1		 3k37B-4b7jA:
33.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.60A 3k39A-4b7jA:
52.5		 3k39A-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 1.35A 3k39A-4b7jA:
52.5		 3k39A-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.59A 3k39B-4b7jA:
52.6		 3k39B-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 1.34A 3k39B-4b7jA:
52.6		 3k39B-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
 0.60A 3k39C-4b7jA:
52.5		 3k39C-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
ARG A 368
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
 1.30A 3k39D-4b7jA:
52.5		 3k39D-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
 G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
 0.61A 3k39D-4b7jA:
52.5		 3k39D-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.61A 3k39E-4b7jA:
52.5		 3k39E-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 1.34A 3k39E-4b7jA:
52.5		 3k39E-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.60A 3k39F-4b7jA:
52.5		 3k39F-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 1.34A 3k39F-4b7jA:
52.5		 3k39F-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.60A 3k39G-4b7jA:
52.5		 3k39G-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 1.32A 3k39G-4b7jA:
52.5		 3k39G-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.60A 3k39H-4b7jA:
52.5		 3k39H-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 1.33A 3k39H-4b7jA:
52.5		 3k39H-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
 0.61A 3k39I-4b7jA:
52.5		 3k39I-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
 0.60A 3k39J-4b7jA:
52.5		 3k39J-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
 0.60A 3k39K-4b7jA:
52.5		 3k39K-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
 0.61A 3k39L-4b7jA:
52.6		 3k39L-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.61A 3k39M-4b7jA:
52.6		 3k39M-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 1.35A 3k39M-4b7jA:
52.6		 3k39M-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		6 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 1.24A 3k39N-4b7jA:
52.6		 3k39N-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.60A 3k39N-4b7jA:
52.6		 3k39N-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.61A 3k39O-4b7jA:
52.5		 3k39O-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 368
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 1.17A 3k39O-4b7jA:
52.5		 3k39O-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 152
GLU A 119
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.9A)
G39  A1470 (-3.5A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 1.49A 3k39P-4b7jA:
52.6		 3k39P-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		6 / 12 ARG A 223
GLU A 228
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-4.0A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 1.26A 3k39P-4b7jA:
52.6		 3k39P-4b7jA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.60A 3k39P-4b7jA:
52.6		 3k39P-4b7jA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		6 / 10 LEU A 426
ASP A 459
GLY A 460
ALA A 461
GLY A 109
ILE A 108
 None
 1.13A 3lzvA-4b7jA:
undetectable		 3lzvA-4b7jA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 HIS A 275
SER A 247
ASP A 199
ASP A 244
 None
G39  A1470 ( 4.3A)
None
None
 1.19A 3n2oC-4b7jA:
undetectable
3n2oD-4b7jA:
undetectable		 3n2oC-4b7jA:
19.85
3n2oD-4b7jA:
19.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.56A 3sanA-4b7jA:
69.8		 3sanA-4b7jA:
48.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_A_ZMRA901_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 ASP A 151
ARG A 152
ARG A 156
TRP A 179
 G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
None
 0.13A 3sanA-4b7jA:
69.8		 3sanA-4b7jA:
48.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.55A 3sanB-4b7jA:
69.7		 3sanB-4b7jA:
48.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_B_ZMRB901_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 ASP A 151
ARG A 152
ARG A 156
TRP A 179
 G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
None
 0.13A 3sanB-4b7jA:
69.7		 3sanB-4b7jA:
48.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 PRO A 167
ILE A 117
SER A 439
ILE A 106
 None
 0.88A 3sfeB-4b7jA:
undetectable
3sfeC-4b7jA:
undetectable		 3sfeB-4b7jA:
18.75
3sfeC-4b7jA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 422
PHE A 406
ALA A  98
THR A 452
 None
 1.09A 3t3sB-4b7jA:
undetectable		 3t3sB-4b7jA:
20.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
SER A 247
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 ( 4.3A)
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.54A 3ti5A-4b7jA:
75.7		 3ti5A-4b7jA:
98.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 228
SER A 247
ARG A 293
ASN A 295
TYR A 402
 None
G39  A1470 ( 4.3A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 1.26A 3ti5A-4b7jA:
75.7		 3ti5A-4b7jA:
98.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
SER A 247
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 ( 4.3A)
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.54A 3ti5B-4b7jA:
75.8		 3ti5B-4b7jA:
98.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 228
SER A 247
ARG A 293
ASN A 295
TYR A 402
 None
G39  A1470 ( 4.3A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 1.25A 3ti5B-4b7jA:
75.8		 3ti5B-4b7jA:
98.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
TRP A 179
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
None
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.61A 3ticA-4b7jA:
64.0		 3ticA-4b7jA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
TRP A 179
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
None
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.45A 3ticA-4b7jA:
64.0		 3ticA-4b7jA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 LEU A 134
ARG A 152
ARG A 156
ARG A 225
 None
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
 0.26A 3ticA-4b7jA:
64.0		 3ticA-4b7jA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.62A 3ticB-4b7jA:
63.9		 3ticB-4b7jA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.46A 3ticB-4b7jA:
63.9		 3ticB-4b7jA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.63A 3ticC-4b7jA:
63.9		 3ticC-4b7jA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.47A 3ticC-4b7jA:
63.9		 3ticC-4b7jA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.63A 3ticD-4b7jA:
64.0		 3ticD-4b7jA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.46A 3ticD-4b7jA:
64.0		 3ticD-4b7jA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 179
 None
G39  A1470 (-3.9A)
None
None
 0.16A 3ticD-4b7jA:
64.0		 3ticD-4b7jA:
45.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 GLY A 440
SER A 439
PHE A 465
LEU A 140
 None
 0.90A 3v7pA-4b7jA:
undetectable		 3v7pA-4b7jA:
21.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
SER A 247
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 ( 4.3A)
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.52A 4b7nA-4b7jA:
75.4		 4b7nA-4b7jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 179
 G39  A1470 (-3.9A)
None
None
 0.11A 4b7nA-4b7jA:
75.4		 4b7nA-4b7jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
SER A 247
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 ( 4.3A)
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.58A 4b7qA-4b7jA:
75.0		 4b7qA-4b7jA:
99.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
SER A 247
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 ( 4.3A)
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.60A 4b7qB-4b7jA:
74.9		 4b7qB-4b7jA:
99.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_B_ZMRB601_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 LEU A 134
ARG A 152
ARG A 156
TRP A 179
 None
G39  A1470 (-3.9A)
None
None
 0.17A 4b7qB-4b7jA:
74.9		 4b7qB-4b7jA:
99.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
SER A 247
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 ( 4.3A)
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.58A 4b7qC-4b7jA:
75.0		 4b7qC-4b7jA:
99.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 228
SER A 247
ARG A 293
ASN A 295
TYR A 402
 None
G39  A1470 ( 4.3A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 1.31A 4b7qC-4b7jA:
75.0		 4b7qC-4b7jA:
99.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
SER A 247
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 ( 4.3A)
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.60A 4b7qD-4b7jA:
74.6		 4b7qD-4b7jA:
99.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.65A 4cpnA-4b7jA:
53.2		 4cpnA-4b7jA:
34.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.64A 4cpnB-4b7jA:
53.1		 4cpnB-4b7jA:
34.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		8 / 12 ARG A 118
GLU A 119
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ASN A 295
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 0.73A 4cpzA-4b7jA:
52.9		 4cpzA-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.47A 4cpzA-4b7jA:
52.9		 4cpzA-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 179
 None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
None
 0.19A 4cpzA-4b7jA:
52.9		 4cpzA-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 0.67A 4cpzB-4b7jA:
52.8		 4cpzB-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.48A 4cpzB-4b7jA:
52.8		 4cpzB-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_B_ZMRB1471_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 152
ARG A 156
TRP A 179
 G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
None
 0.19A 4cpzB-4b7jA:
52.8		 4cpzB-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.61A 4cpzC-4b7jA:
52.9		 4cpzC-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 179
 G39  A1470 (-3.9A)
None
None
 0.18A 4cpzC-4b7jA:
52.9		 4cpzC-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		8 / 12 ARG A 118
GLU A 119
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ASN A 295
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 0.71A 4cpzD-4b7jA:
52.7		 4cpzD-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.51A 4cpzD-4b7jA:
52.7		 4cpzD-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_D_ZMRD1471_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 152
ARG A 156
TRP A 179
 G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
None
 0.16A 4cpzD-4b7jA:
52.7		 4cpzD-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		8 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-4.5A)
 0.72A 4cpzE-4b7jA:
52.7		 4cpzE-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.50A 4cpzE-4b7jA:
52.7		 4cpzE-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 179
 G39  A1470 (-3.9A)
None
None
 0.12A 4cpzE-4b7jA:
52.7		 4cpzE-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ASN A 295
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 0.73A 4cpzF-4b7jA:
52.8		 4cpzF-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.50A 4cpzF-4b7jA:
52.8		 4cpzF-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 179
 G39  A1470 (-3.9A)
None
None
 0.16A 4cpzF-4b7jA:
52.8		 4cpzF-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ASN A 295
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 0.68A 4cpzG-4b7jA:
52.5		 4cpzG-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.44A 4cpzG-4b7jA:
52.5		 4cpzG-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 179
 G39  A1470 (-3.9A)
None
None
 0.18A 4cpzG-4b7jA:
52.5		 4cpzG-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ASN A 295
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 ( 3.7A)
G39  A1470 (-4.5A)
 0.76A 4cpzH-4b7jA:
52.7		 4cpzH-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.57A 4cpzH-4b7jA:
52.7		 4cpzH-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 179
 G39  A1470 (-3.9A)
None
None
 0.20A 4cpzH-4b7jA:
52.7		 4cpzH-4b7jA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		8 / 12 ARG A 118
ASP A 151
ARG A 152
ARG A 225
GLU A 228
GLU A 277
GLU A 278
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-4.5A)
 0.59A 4i00A-4b7jA:
64.0		 4i00A-4b7jA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 152
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.42A 4i00A-4b7jA:
64.0		 4i00A-4b7jA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 223
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-4.0A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 1.08A 4i00A-4b7jA:
64.0		 4i00A-4b7jA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 LEU A 134
ARG A 156
TRP A 179
ASN A 295
 None
None
None
G39  A1470 ( 3.7A)
 0.95A 4i00A-4b7jA:
64.0		 4i00A-4b7jA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.61A 4mwrA-4b7jA:
64.3		 4mwrA-4b7jA:
40.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 156
ARG A 225
GLU A 228
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.43A 4mwrA-4b7jA:
64.3		 4mwrA-4b7jA:
40.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 LEU A 134
ASP A 151
ARG A 152
TRP A 179
 None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
 0.26A 4mwrA-4b7jA:
64.3		 4mwrA-4b7jA:
40.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 179
ARG A 225
GLU A 277
GLU A 278
ARG A 293
TYR A 402
 G39  A1470 (-3.5A)
None
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
None
G39  A1470 (-4.4A)
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-4.5A)
 0.42A 4mwvA-4b7jA:
64.2		 4mwvA-4b7jA:
40.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
GLU A 228
ARG A 368
 G39  A1470 (-3.1A)
None
G39  A1470 (-3.0A)
 0.20A 4mwvA-4b7jA:
64.2		 4mwvA-4b7jA:
40.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.62A 4mwxA-4b7jA:
64.2		 4mwxA-4b7jA:
40.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
TRP A 179
SER A 180
ARG A 225
GLU A 228
GLU A 277
GLU A 278
TYR A 402
 G39  A1470 (-3.5A)
None
G39  A1470 (-3.9A)
None
None
G39  A1470 ( 4.5A)
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-4.5A)
 0.41A 4mx0A-4b7jA:
64.2		 4mx0A-4b7jA:
40.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ASP A 151
ARG A 368
 G39  A1470 (-3.1A)
G39  A1470 (-3.7A)
G39  A1470 (-3.0A)
 0.23A 4mx0A-4b7jA:
64.2		 4mx0A-4b7jA:
40.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		6 / 10 LEU A 426
ASP A 459
GLY A 460
ALA A 461
GLY A 109
ILE A 108
 None
 1.17A 4njtB-4b7jA:
undetectable		 4njtB-4b7jA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 9 LEU A 426
ASP A 459
GLY A 460
ALA A 461
ILE A 108
 None
 1.13A 4njtD-4b7jA:
undetectable		 4njtD-4b7jA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 9 LEU A 426
ASP A 459
ALA A 461
GLY A 109
ILE A 108
 None
 1.03A 4q1wA-4b7jA:
undetectable		 4q1wA-4b7jA:
11.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ASN A 295
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.69A 4wa5A-4b7jA:
67.8		 4wa5A-4b7jA:
49.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_2
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 ARG A 152
ARG A 156
TRP A 179
ARG A 225
 G39  A1470 (-3.9A)
None
None
G39  A1470 (-4.4A)
 0.65A 4wa5A-4b7jA:
67.8		 4wa5A-4b7jA:
49.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ILE A 117
GLY A 440
GLU A 175
SER A 123
ILE A 122
 None
 1.20A 5igwA-4b7jA:
undetectable		 5igwA-4b7jA:
18.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 225
GLU A 228
GLU A 277
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.54A 5l17A-4b7jA:
64.5		 5l17A-4b7jA:
42.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 118
GLU A 278
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-4.2A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.33A 6ekuA-4b7jA:
12.0		 6ekuA-4b7jA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 ASN A 329
ASN A 341
PRO A 328
ILE A 365
 None
 1.11A 6h7uA-4b7jA:
undetectable		 6h7uA-4b7jA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 4b7j NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 152
ARG A 156
ARG A 225
GLU A 228
GLU A 277
ARG A 293
ARG A 368
TYR A 402
 G39  A1470 (-3.1A)
G39  A1470 (-3.5A)
G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
None
G39  A1470 (-4.4A)
None
G39  A1470 (-3.7A)
G39  A1470 (-2.9A)
G39  A1470 (-3.0A)
G39  A1470 (-4.5A)
 0.59A 6hcxA-4b7jA:
64.4		 6hcxA-4b7jA:
10.72