SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b8e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 4b8e E3 UBIQUITIN/ISG15
LIGASE TRIM25
(Mus
musculus) 		4 / 7 ALA A 471
TYR A 493
SER A 478
ALA A 484
 None
 1.02A 1k5qA-4b8eA:
undetectable
1k5qB-4b8eA:
undetectable		 1k5qA-4b8eA:
21.28
1k5qB-4b8eA:
16.42