SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b8v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 4b8v EXTRACELLULAR
PROTEIN 6
(Passalora
fulva) 		5 / 10 ILE A 185
ILE A 147
LEU A 156
ASN A 171
ILE A 164
 None
NAG  A1202 (-4.6A)
None
None
NAG  A1200 (-4.1A)
 1.21A 2nnhB-4b8vA:
undetectable		 2nnhB-4b8vA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 4b8v EXTRACELLULAR
PROTEIN 6
(Passalora
fulva) 		5 / 11 VAL A 131
PRO A 132
PRO A  85
ILE A 167
PRO A 188
 None
 1.14A 3ganA-4b8vA:
undetectable		 3ganA-4b8vA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 4b8v EXTRACELLULAR
PROTEIN 6
(Passalora
fulva) 		4 / 8 LEU A  55
ILE A  57
GLY A  33
ILE A  34
 None
None
None
NDG  A1199 ( 4.6A)
 0.88A 3wxoA-4b8vA:
undetectable		 3wxoA-4b8vA:
15.93