SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4b96 CELLULOSE BINDING
DOMAIN-CONTAINING
PROTEIN
([Clostridium]
clariflavum) 		4 / 8 LEU A  37
PRO A  96
TYR A  60
VAL A 103
 None
 0.97A 1fduB-4b96A:
undetectable		 1fduB-4b96A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4b96 CELLULOSE BINDING
DOMAIN-CONTAINING
PROTEIN
([Clostridium]
clariflavum) 		5 / 11 VAL A  57
ALA A  56
PHE A  55
LEU A  86
PHE A  25
 None
 1.21A 1uduA-4b96A:
undetectable		 1uduA-4b96A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4b96 CELLULOSE BINDING
DOMAIN-CONTAINING
PROTEIN
([Clostridium]
clariflavum) 		4 / 8 HIS A   9
ASN A 127
TRP A 133
PHE A 123
 None
 1.19A 3ccfA-4b96A:
undetectable		 3ccfA-4b96A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4b96 CELLULOSE BINDING
DOMAIN-CONTAINING
PROTEIN
([Clostridium]
clariflavum) 		4 / 8 HIS A   9
ASN A 127
TRP A 133
PHE A 123
 None
 1.22A 3ccfB-4b96A:
undetectable		 3ccfB-4b96A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 4b96 CELLULOSE BINDING
DOMAIN-CONTAINING
PROTEIN
([Clostridium]
clariflavum) 		4 / 8 LEU A  37
VAL A 103
VAL A  42
LEU A  62
 None
 1.16A 4q0bA-4b96A:
1.4		 4q0bA-4b96A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4b96 CELLULOSE BINDING
DOMAIN-CONTAINING
PROTEIN
([Clostridium]
clariflavum) 		6 / 10 TYR A  60
ILE A  27
GLY A  93
PHE A  90
SER A  61
VAL A  40
 None
 1.42A 5i6xA-4b96A:
undetectable		 5i6xA-4b96A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4b96 CELLULOSE BINDING
DOMAIN-CONTAINING
PROTEIN
([Clostridium]
clariflavum) 		4 / 5 LEU A  37
LYS A  92
LEU A  62
TYR A  60
 None
 1.41A 5ki6A-4b96A:
undetectable		 5ki6A-4b96A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4b96 CELLULOSE BINDING
DOMAIN-CONTAINING
PROTEIN
([Clostridium]
clariflavum) 		3 / 3 TYR A  10
LEU A 124
ASP A 134
 None
 0.81A 5zv2B-4b96A:
undetectable		 5zv2B-4b96A:
20.41