SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_C_STRC601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	4b9f	CELLULOSOMAL-SCAFFOL DING PROTEIN A (Ruminiclostridiu m thermocellum)	5 / 12	PHE A 96 ILE A 32 ILE A 109 VAL A 24 VAL A 4	None	1.10A	4nkxC-4b9fA: undetectable	4nkxC-4b9fA: 16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_B_SAMB601_0 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	4b9f	CELLULOSOMAL-SCAFFOL DING PROTEIN A (Ruminiclostridiu m thermocellum)	5 / 12	ALA A 58 ILE A 60 ASN A 68 ASN A 73 PHE A 96	None	1.04A	4obwB-4b9fA: undetectable	4obwB-4b9fA: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BYJ_A_OQRA302_0 (SULFOTRANSFERASE)	4b9f	CELLULOSOMAL-SCAFFOL DING PROTEIN A (Ruminiclostridiu m thermocellum)	5 / 12	PHE A 22 ILE A 109 PHE A 96 LEU A 92 THR A 77	None	1.03A	5byjA-4b9fA: undetectable	5byjA-4b9fA: 20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCE_A_RITA602_2 (CYTOCHROME P450 3A4)	4b9f	CELLULOSOMAL-SCAFFOL DING PROTEIN A (Ruminiclostridiu m thermocellum)	4 / 6	ARG A 40 PHE A 78 ILE A 94 THR A 38	None	1.00A	5vceA-4b9fA: undetectable	5vceA-4b9fA: 16.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4NKX_C_STRC601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","4b9f","CELLULOSOMAL-SCAFFOLDING PROTEIN A","Ruminiclostridium thermocellum",5,"PHE A  96;ILE A  32;ILE A 109;VAL A  24;VAL A   4","None","1.10A","4nkxC-4b9fA:undetectable","4nkxC-4b9fA:16.19"],["4OBW_B_SAMB601_0","2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL","4b9f","CELLULOSOMAL-SCAFFOLDING PROTEIN A","Ruminiclostridium thermocellum",5,"ALA A  58;ILE A  60;ASN A  68;ASN A  73;PHE A  96","None","1.04A","4obwB-4b9fA:undetectable","4obwB-4b9fA:21.40"],["5BYJ_A_OQRA302_0","SULFOTRANSFERASE","4b9f","CELLULOSOMAL-SCAFFOLDING PROTEIN A","Ruminiclostridium thermocellum",5,"PHE A  22;ILE A 109;PHE A  96;LEU A  92;THR A  77","None","1.03A","5byjA-4b9fA:undetectable","5byjA-4b9fA:20.26"],["5VCE_A_RITA602_2","CYTOCHROME P450 3A4","4b9f","CELLULOSOMAL-SCAFFOLDING PROTEIN A","Ruminiclostridium thermocellum",4,"ARG A  40;PHE A  78;ILE A  94;THR A  38","None","1.00A","5vceA-4b9fA:undetectable","5vceA-4b9fA:16.92"]]