SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 4b9g CS6 FIMBRIAL SUBUNIT
B, CS6 FIMBRIAL
SUBUNIT A
(Escherichia
coli) 		5 / 12 VAL A  41
LEU A 134
SER A 137
PHE A 138
PHE A 111
 None
 1.14A 1fdsA-4b9gA:
undetectable		 1fdsA-4b9gA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDW_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4b9g CS6 FIMBRIAL SUBUNIT
B, CS6 FIMBRIAL
SUBUNIT A
(Escherichia
coli) 		5 / 10 VAL A  41
LEU A 134
SER A 137
VAL A  52
PHE A 111
 None
 1.32A 1fdwA-4b9gA:
undetectable		 1fdwA-4b9gA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4b9g CS6 FIMBRIAL SUBUNIT
B, CS6 FIMBRIAL
SUBUNIT A
(Escherichia
coli) 		4 / 7 PRO A  56
PHE A  93
ILE A  54
GLY A  96
 None
 0.84A 2y7kA-4b9gA:
undetectable		 2y7kA-4b9gA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 4b9g CS6 FIMBRIAL SUBUNIT
B, CS6 FIMBRIAL
SUBUNIT A
(Escherichia
coli) 		3 / 3 TYR A 130
ASP A  31
ASP A  29
 None
 0.74A 4a6eA-4b9gA:
undetectable		 4a6eA-4b9gA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 4b9g CS6 FIMBRIAL SUBUNIT
B, CS6 FIMBRIAL
SUBUNIT A
(Escherichia
coli) 		4 / 7 THR A 158
TYR A  39
PRO A  25
THR A  40
 None
 1.26A 5b6iA-4b9gA:
undetectable		 5b6iA-4b9gA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 4b9g CS6 FIMBRIAL SUBUNIT
B, CS6 FIMBRIAL
SUBUNIT A
(Escherichia
coli) 		4 / 7 LEU A  38
THR A 158
PRO A  32
ILE A 160
 None
 1.07A 5fxtA-4b9gA:
undetectable		 5fxtA-4b9gA:
19.67