SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M9J_A_CLWA906_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	4b9x	TUDOR DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	4 / 5	VAL A 797 TYR A 724 MET A 717 GLU A 722	None	1.45A	1m9jA-4b9xA: undetectable	1m9jA-4b9xA: 20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M9J_B_CLWB907_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	4b9x	TUDOR DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	4 / 5	VAL A 797 TYR A 724 MET A 717 GLU A 722	None	1.48A	1m9jB-4b9xA: undetectable	1m9jB-4b9xA: 20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_B_SVRB512_1 (PHOSPHOLIPASE A2)	4b9x	TUDOR DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	4 / 5	VAL A 855 VAL A 856 THR A 709 ARG A 854	None	1.07A	3bjwA-4b9xA: undetectable	3bjwA-4b9xA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_F_SVRF509_1 (PHOSPHOLIPASE A2)	4b9x	TUDOR DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	4 / 5	VAL A 855 VAL A 856 THR A 709 ARG A 854	None	1.08A	3bjwC-4b9xA: undetectable	3bjwC-4b9xA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_G_SVRG506_1 (PHOSPHOLIPASE A2)	4b9x	TUDOR DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	4 / 8	VAL A 855 VAL A 856 GLY A 864 ARG A 854	None	0.96A	3bjwA-4b9xA: undetectable	3bjwA-4b9xA: 17.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1M9J_A_CLWA906_1","ENDOTHELIAL NITRIC-OXIDE SYNTHASE","4b9x","TUDOR DOMAIN-CONTAINING PROTEIN 1","Mus musculus",4,"VAL A 797;TYR A 724;MET A 717;GLU A 722","None","1.45A","1m9jA-4b9xA:undetectable","1m9jA-4b9xA:20.71"],["1M9J_B_CLWB907_1","ENDOTHELIAL NITRIC-OXIDE SYNTHASE","4b9x","TUDOR DOMAIN-CONTAINING PROTEIN 1","Mus musculus",4,"VAL A 797;TYR A 724;MET A 717;GLU A 722","None","1.48A","1m9jB-4b9xA:undetectable","1m9jB-4b9xA:20.71"],["3BJW_B_SVRB512_1","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","4b9x","TUDOR DOMAIN-CONTAINING PROTEIN 1","Mus musculus",4,"VAL A 855;VAL A 856;THR A 709;ARG A 854","None","1.07A","3bjwA-4b9xA:undetectable","3bjwA-4b9xA:17.05"],["3BJW_F_SVRF509_1","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","4b9x","TUDOR DOMAIN-CONTAINING PROTEIN 1","Mus musculus",4,"VAL A 855;VAL A 856;THR A 709;ARG A 854","None","1.08A","3bjwC-4b9xA:undetectable","3bjwC-4b9xA:17.05"],["3BJW_G_SVRG506_1","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","4b9x","TUDOR DOMAIN-CONTAINING PROTEIN 1","Mus musculus",4,"VAL A 855;VAL A 856;GLY A 864;ARG A 854","None","0.96A","3bjwA-4b9xA:undetectable","3bjwA-4b9xA:17.05"]]