SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4b9y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 4 HIS A 769
LEU A 800
LEU A 802
LEU A 811
 None
 1.25A 1a4lD-4b9yA:
3.8		 1a4lD-4b9yA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 11 ARG A 231
LEU A  70
GLU A  68
PHE A 135
GLY A 134
 SO4  A1820 (-3.1A)
None
SO4  A1820 ( 4.9A)
None
None
 1.31A 1cmaA-4b9yA:
undetectable
1cmaB-4b9yA:
undetectable		 1cmaA-4b9yA:
8.45
1cmaB-4b9yA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		3 / 3 GLN A 580
ILE A 475
HIS A 507
 None
 0.71A 1fm9A-4b9yA:
undetectable		 1fm9A-4b9yA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 7 GLY A 585
THR A 253
THR A 250
ILE A 246
 None
 0.98A 1gtnJ-4b9yA:
undetectable
1gtnK-4b9yA:
undetectable		 1gtnJ-4b9yA:
7.22
1gtnK-4b9yA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 11 LEU A 127
ALA A 118
ALA A 130
LEU A 236
HIS A 100
 None
None
None
None
SO4  A1823 (-3.9A)
 1.30A 1iiuA-4b9yA:
undetectable		 1iiuA-4b9yA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		3 / 3 GLN A 580
ILE A 475
HIS A 507
 None
 0.70A 1k74A-4b9yA:
undetectable		 1k74A-4b9yA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 11 ARG A 231
LEU A  70
GLU A  68
PHE A 135
GLY A 134
 SO4  A1820 (-3.1A)
None
SO4  A1820 ( 4.9A)
None
None
 1.35A 1mjqA-4b9yA:
undetectable
1mjqB-4b9yA:
undetectable		 1mjqA-4b9yA:
8.45
1mjqB-4b9yA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 11 GLU A  68
LEU A  83
ALA A  82
PHE A  81
GLY A 468
 SO4  A1820 ( 4.9A)
None
None
None
None
 1.12A 1mjqA-4b9yA:
undetectable
1mjqB-4b9yA:
undetectable		 1mjqA-4b9yA:
8.45
1mjqB-4b9yA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 10 ARG A 231
LEU A  70
GLU A  68
PHE A 135
GLY A 134
 SO4  A1820 (-3.1A)
None
SO4  A1820 ( 4.9A)
None
None
 1.40A 1mjqC-4b9yA:
undetectable
1mjqD-4b9yA:
undetectable		 1mjqC-4b9yA:
8.45
1mjqD-4b9yA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ALA A  82
PHE A  81
GLY A 468
GLU A  68
LEU A  83
 None
None
None
SO4  A1820 ( 4.9A)
None
 1.08A 1mjqC-4b9yA:
undetectable
1mjqD-4b9yA:
undetectable		 1mjqC-4b9yA:
8.45
1mjqD-4b9yA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 10 GLU A  68
LEU A  83
ALA A  82
PHE A  81
GLY A 468
 SO4  A1820 ( 4.9A)
None
None
None
None
 1.13A 1mjqG-4b9yA:
undetectable
1mjqH-4b9yA:
undetectable		 1mjqG-4b9yA:
8.45
1mjqH-4b9yA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 GLY A 669
VAL A 636
PHE A 671
LEU A 727
PHE A 638
 None
 1.34A 1nw3A-4b9yA:
undetectable		 1nw3A-4b9yA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 TYR A 273
GLY A 512
PHE A 513
ARG A 483
 None
 1.29A 2a3cB-4b9yA:
12.5		 2a3cB-4b9yA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_A_ADNA901_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 10 HIS A 419
HIS A 434
ILE A 382
ALA A 436
ASN A 435
 None
 1.48A 2gl0A-4b9yA:
undetectable
2gl0B-4b9yA:
undetectable		 2gl0A-4b9yA:
11.17
2gl0B-4b9yA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 11 HIS A 419
HIS A 434
ILE A 382
ALA A 436
ASN A 435
 None
 1.44A 2gl0B-4b9yA:
undetectable
2gl0C-4b9yA:
undetectable		 2gl0B-4b9yA:
11.17
2gl0C-4b9yA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 HIS A 419
HIS A 434
ILE A 382
ALA A 436
ASN A 435
 None
 1.42A 2gl0D-4b9yA:
undetectable
2gl0E-4b9yA:
undetectable		 2gl0D-4b9yA:
11.17
2gl0E-4b9yA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 4 SER A 469
GLY A 468
HIS A 434
ASP A 429
 None
 1.29A 2oxtC-4b9yA:
undetectable		 2oxtC-4b9yA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 7 GLN A 534
TYR A 530
TYR A 181
ILE A 161
 None
 1.08A 2ph9A-4b9yA:
undetectable
2ph9B-4b9yA:
undetectable		 2ph9A-4b9yA:
15.69
2ph9B-4b9yA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		8 / 12 ASP A 299
ILE A 341
ASP A 412
ARG A 463
ASP A 480
PHE A 513
ALA A 514
HIS A 540
 None
 0.57A 2qmjA-4b9yA:
39.5		 2qmjA-4b9yA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ASP A 509
PHE A 513
ALA A 514
 None
 1.17A 2qmjA-4b9yA:
39.5		 2qmjA-4b9yA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 5 PRO A 751
ARG A 808
ARG A 742
ASP A 723
 None
EDO  A1832 (-3.9A)
None
None
 1.22A 2rhmB-4b9yA:
undetectable		 2rhmB-4b9yA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 PHE A 271
ASP A 299
ASP A 412
ASP A 480
PHE A 513
HIS A 540
 None
 0.47A 2x2iA-4b9yA:
32.4		 2x2iA-4b9yA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ASP A 412
ASP A 480
PHE A 513
HIS A 540
 None
 0.44A 2x2iB-4b9yA:
33.8		 2x2iB-4b9yA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 PHE A 271
TRP A 410
ARG A 463
TRP A 477
 None
 0.47A 2x2iB-4b9yA:
33.8		 2x2iB-4b9yA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ASP A 412
ASP A 480
PHE A 513
HIS A 540
 None
 0.37A 2x2iC-4b9yA:
32.9		 2x2iC-4b9yA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 5 PHE A 271
TRP A 410
ARG A 463
TRP A 477
 None
 0.39A 2x2iC-4b9yA:
32.9		 2x2iC-4b9yA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 PHE A 271
ASP A 299
ASP A 412
ASP A 480
PHE A 513
HIS A 540
 None
 0.55A 2x2iD-4b9yA:
34.9		 2x2iD-4b9yA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 THR A 253
GLY A 468
GLY A 502
LEU A 501
PHE A 190
PRO A 193
 None
 1.24A 2y7kD-4b9yA:
undetectable		 2y7kD-4b9yA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 ARG A 115
ILE A 112
LEU A  48
GLU A  96
 None
 1.05A 2ya7A-4b9yA:
undetectable		 2ya7A-4b9yA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 ARG A 115
ILE A 112
LEU A  48
GLU A  96
 None
 1.05A 2ya7B-4b9yA:
undetectable		 2ya7B-4b9yA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 ARG A 115
ILE A 112
LEU A  48
GLU A  96
 None
 1.07A 2ya7D-4b9yA:
undetectable		 2ya7D-4b9yA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 7 GLY A 390
ALA A 356
ALA A 359
VAL A 346
 None
 0.77A 3a2qA-4b9yA:
undetectable		 3a2qA-4b9yA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 7 THR A 250
VAL A 252
THR A 253
ILE A 202
 None
 0.87A 3deuA-4b9yA:
undetectable		 3deuA-4b9yA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 7 ASN A 175
TYR A 174
HIS A 425
ALA A 430
 None
 1.23A 3frqB-4b9yA:
undetectable		 3frqB-4b9yA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IIZ_A_SAMA1501_0
(BIOTIN SYNTHETASE,
PUTATIVE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 GLY A 216
ILE A 119
TYR A 201
LEU A 129
TYR A 121
 None
 1.28A 3iizA-4b9yA:
5.1		 3iizA-4b9yA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 8 GLY A  47
ILE A 112
PHE A 135
PHE A 144
 None
 0.82A 3ko0B-4b9yA:
undetectable
3ko0J-4b9yA:
undetectable		 3ko0B-4b9yA:
7.71
3ko0J-4b9yA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 8 GLY A  47
ILE A 112
PHE A 135
PHE A 144
 None
 0.89A 3ko0K-4b9yA:
undetectable
3ko0S-4b9yA:
undetectable		 3ko0K-4b9yA:
7.71
3ko0S-4b9yA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ASP A 480
PHE A 513
HIS A 540
 None
 1.41A 3l4wA-4b9yA:
38.4		 3l4wA-4b9yA:
26.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		8 / 12 ASP A 299
ILE A 341
TRP A 410
ASP A 412
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.38A 3l4wA-4b9yA:
38.4		 3l4wA-4b9yA:
26.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 PHE A 267
PHE A 459
THR A 295
VAL A 297
 None
 1.23A 3lb3B-4b9yA:
undetectable		 3lb3B-4b9yA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 ALA A 363
ILE A 382
HIS A 419
VAL A 433
 None
 1.20A 3nneG-4b9yA:
undetectable		 3nneG-4b9yA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		8 / 12 ASP A 299
ILE A 341
ASP A 412
ARG A 463
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.49A 3phaA-4b9yA:
39.9		 3phaA-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 12 ASP A 299
ILE A 341
ASP A 412
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.46A 3phaB-4b9yA:
39.5		 3phaB-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ASP A 480
PHE A 513
HIS A 540
 None
 1.33A 3phaB-4b9yA:
39.5		 3phaB-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 12 ASP A 299
ASP A 412
ARG A 463
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.45A 3phaC-4b9yA:
34.2		 3phaC-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ASP A 299
ILE A 341
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 1.36A 3phaC-4b9yA:
34.2		 3phaC-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ASP A 299
ASP A 412
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.41A 3phaD-4b9yA:
34.5		 3phaD-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ASP A 480
PHE A 513
HIS A 540
 None
 1.30A 3phaD-4b9yA:
34.5		 3phaD-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ASP A 299
ILE A 341
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 1.31A 3pocA-4b9yA:
34.4		 3pocA-4b9yA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 12 ASP A 299
ILE A 341
ARG A 463
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.46A 3pocA-4b9yA:
34.4		 3pocA-4b9yA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ARG A 538
ASP A 509
PHE A 513
 None
 1.35A 3pocA-4b9yA:
34.4		 3pocA-4b9yA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
TRP A 410
PHE A 513
HIS A 540
 None
 0.89A 3pocA-4b9yA:
34.4		 3pocA-4b9yA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 12 ASP A 299
ILE A 341
ARG A 463
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.44A 3pocB-4b9yA:
38.6		 3pocB-4b9yA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ASP A 480
PHE A 513
HIS A 540
 None
 1.30A 3pocB-4b9yA:
38.6		 3pocB-4b9yA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
TRP A 410
PHE A 513
HIS A 540
 None
 0.90A 3pocB-4b9yA:
38.6		 3pocB-4b9yA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 VAL A 675
TYR A 684
GLU A 708
ILE A 706
 None
 0.94A 3q5sA-4b9yA:
undetectable		 3q5sA-4b9yA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_D_DXCD92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 5 VAL A 467
GLU A  87
LYS A  62
PHE A 249
 None
 1.32A 3rv5C-4b9yA:
undetectable
3rv5D-4b9yA:
undetectable		 3rv5C-4b9yA:
8.28
3rv5D-4b9yA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 5 ILE A  57
THR A  52
THR A  51
PHE A 117
 None
 1.22A 3snfA-4b9yA:
undetectable		 3snfA-4b9yA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 12 ASP A 299
ILE A 341
ASP A 412
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.53A 3topA-4b9yA:
34.3		 3topA-4b9yA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 12 ASP A 299
ILE A 341
ASP A 412
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.52A 3topB-4b9yA:
34.3		 3topB-4b9yA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		8 / 12 ASP A 299
ILE A 341
TRP A 410
ASP A 412
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.35A 3w37A-4b9yA:
43.0		 3w37A-4b9yA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		8 / 12 ASP A 299
ILE A 341
TRP A 410
ASP A 412
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.38A 3welA-4b9yA:
43.2		 3welA-4b9yA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ASP A 299
ASP A 412
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.44A 3wemA-4b9yA:
42.3		 3wemA-4b9yA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ASP A 480
PHE A 513
HIS A 540
 None
 1.36A 3wemA-4b9yA:
42.3		 3wemA-4b9yA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ASP A 480
PHE A 513
HIS A 540
 None
 1.37A 3wenA-4b9yA:
42.6		 3wenA-4b9yA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 12 ASP A 299
TRP A 410
ASP A 412
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.47A 3wenA-4b9yA:
42.6		 3wenA-4b9yA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ASP A 480
PHE A 513
HIS A 540
 None
 1.37A 3weoA-4b9yA:
37.8		 3weoA-4b9yA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 12 ASP A 299
TRP A 410
ASP A 412
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.39A 3weoA-4b9yA:
37.8		 3weoA-4b9yA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 5 THR A 556
ILE A 525
LYS A 521
GLU A 522
 None
 1.47A 4acbC-4b9yA:
2.5		 4acbC-4b9yA:
20.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		12 / 12 TYR A 179
ASP A 299
LEU A 300
ILE A 341
TYR A 376
ASP A 412
LEU A 413
GLU A 417
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.42A 4b9zA-4b9yA:
66.0		 4b9zA-4b9yA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 TYR A 376
ASP A 412
LEU A 413
GLU A 417
PHE A 271
 None
 1.34A 4b9zA-4b9yA:
66.0		 4b9zA-4b9yA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B9Z_A_ACRA1818_2
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 5 PHE A 271
PHE A 377
TRP A 410
TRP A 477
GLN A 542
 None
 0.47A 4b9zA-4b9yA:
66.0		 4b9zA-4b9yA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 4 ASN A 207
ALA A 227
GLY A 230
THR A 432
 None
None
EDO  A1829 (-3.4A)
EDO  A1829 (-3.8A)
 1.36A 4bboC-4b9yA:
undetectable		 4bboC-4b9yA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 5 HIS A 178
GLN A 187
GLY A 186
SER A 185
 EDO  A1834 (-4.5A)
None
EDO  A1834 (-3.6A)
EDO  A1834 ( 4.1A)
 1.12A 4fu8A-4b9yA:
undetectable		 4fu8A-4b9yA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 8 LEU A 566
PHE A 533
TYR A 537
PRO A 562
 PG4  A1833 (-4.2A)
None
None
EDO  A1831 (-4.0A)
 1.21A 4j7uD-4b9yA:
2.0		 4j7uD-4b9yA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JXC_A_SAMA402_0
(FEFE-HYDROGENASE
MATURASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 GLY A 216
ILE A 119
TYR A 201
LEU A 129
TYR A 121
 None
 1.28A 4jxcA-4b9yA:
7.9		 4jxcA-4b9yA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 5 LEU A 362
ASP A 355
ARG A 352
ILE A 397
 None
 1.34A 4mwrA-4b9yA:
undetectable		 4mwrA-4b9yA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ILE A 296
THR A 338
THR A 279
LEU A 340
PHE A 321
 None
 1.21A 4pbhA-4b9yA:
undetectable		 4pbhA-4b9yA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		3 / 3 PRO A 673
MET A 672
TYR A 573
 None
 0.90A 4qa0B-4b9yA:
undetectable		 4qa0B-4b9yA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		3 / 3 PRO A 673
MET A 672
TYR A 573
 None
 0.93A 4qa0A-4b9yA:
undetectable		 4qa0A-4b9yA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		3 / 3 PRO A 673
MET A 672
TYR A 573
 None
 0.93A 4qa2B-4b9yA:
undetectable		 4qa2B-4b9yA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		3 / 3 GLN A 113
HIS A 100
ARG A 111
 None
SO4  A1823 (-3.9A)
SO4  A1823 ( 4.6A)
 1.18A 4qyqA-4b9yA:
undetectable		 4qyqA-4b9yA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		3 / 3 GLN A 113
HIS A 100
ARG A 111
 None
SO4  A1823 (-3.9A)
SO4  A1823 ( 4.6A)
 1.19A 4qyqB-4b9yA:
undetectable		 4qyqB-4b9yA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 ARG A 463
ASP A 412
VAL A 481
ASP A 509
 None
 1.42A 4xqeA-4b9yA:
undetectable		 4xqeA-4b9yA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 ASP A 165
TYR A 201
TYR A 242
LEU A 245
 None
 1.32A 5bmvB-4b9yA:
undetectable		 5bmvB-4b9yA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ALA A 577
LEU A 588
ILE A 154
LEU A 245
PHE A 594
 None
 1.21A 5eshA-4b9yA:
undetectable		 5eshA-4b9yA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ILE A 706
GLU A 705
GLY A 704
THR A 756
LEU A 740
 None
 1.18A 5fhzD-4b9yA:
undetectable		 5fhzD-4b9yA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 8 GLY A 414
GLU A 415
ASP A 480
TRP A 477
 None
 1.02A 5gqbA-4b9yA:
12.0		 5gqbA-4b9yA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_A_GCSA801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 GLY A 479
ASP A 412
LEU A 413
GLU A 417
GLU A 415
 None
 1.39A 5gsmA-4b9yA:
13.2		 5gsmA-4b9yA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_B_GCSB801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 GLY A 479
ASP A 412
LEU A 413
GLU A 417
GLU A 415
 None
 1.37A 5gsmB-4b9yA:
11.1		 5gsmB-4b9yA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_D_EVPD102_1
(DNA TOPOISOMERASE
2-ALPHA)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 4 GLY A 304
ASP A 317
ARG A 274
MET A 461
 None
None
SO4  A1825 (-3.1A)
None
 1.44A 5gwkB-4b9yA:
undetectable		 5gwkB-4b9yA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 LEU A 740
LEU A 758
LEU A 727
THR A 726
PRO A 572
 None
 1.15A 5hnwB-4b9yA:
undetectable		 5hnwB-4b9yA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 LEU A 740
LEU A 758
LEU A 727
THR A 726
PRO A 572
 None
 1.17A 5hnyB-4b9yA:
undetectable		 5hnyB-4b9yA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ASP A 480
PHE A 513
HIS A 540
 None
 1.41A 5iefA-4b9yA:
38.1		 5iefA-4b9yA:
27.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 12 ASP A 299
ILE A 341
TRP A 410
ASP A 412
ASP A 480
PHE A 513
HIS A 540
 None
 0.46A 5iefA-4b9yA:
38.1		 5iefA-4b9yA:
27.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ILE A 341
PHE A 377
ASP A 480
PHE A 513
HIS A 540
 None
 1.27A 5iefA-4b9yA:
38.1		 5iefA-4b9yA:
27.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_2
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 4 ARG A 463
TRP A 477
ASP A 509
ARG A 538
 None
 0.86A 5iefA-4b9yA:
38.1		 5iefA-4b9yA:
27.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCW_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE P)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 4 PHE A 135
GLN A 136
ILE A 142
ARG A  72
 None
 1.40A 5jcwA-4b9yA:
0.0		 5jcwA-4b9yA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCW_B_ACTB303_0
(GLUTATHIONE
S-TRANSFERASE P)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 4 PHE A 135
GLN A 136
ILE A 142
ARG A  72
 None
 1.39A 5jcwB-4b9yA:
0.0		 5jcwB-4b9yA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		9 / 12 ASP A 299
LEU A 300
ILE A 341
TRP A 410
ASP A 412
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.63A 5nn6A-4b9yA:
45.0		 5nn6A-4b9yA:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		9 / 12 ASP A 299
LEU A 300
ILE A 341
TRP A 410
ASP A 412
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 0.59A 5nn8A-4b9yA:
34.8		 5nn8A-4b9yA:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 9 PRO A 587
ILE A 506
GLY A 502
LEU A 496
ALA A 495
 None
 0.99A 5o96A-4b9yA:
undetectable
5o96B-4b9yA:
undetectable		 5o96A-4b9yA:
15.41
5o96B-4b9yA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 10 TRP A 410
ASP A 412
ARG A 463
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.40A 5x7pA-4b9yA:
21.5		 5x7pA-4b9yA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 SER A 716
GLU A 708
ASP A 687
ASP A 710
 None
 1.20A 5zw4A-4b9yA:
2.1		 5zw4A-4b9yA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 4 PRO A 539
MET A 461
GLY A 411
VAL A 297
 None
 1.04A 6ak3A-4b9yA:
undetectable		 6ak3A-4b9yA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP9_A_ACTA304_0
(GLUTATHIONE
S-TRANSFERASE P)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 4 PHE A 135
GLN A 136
ILE A 142
ARG A  72
 None
 1.38A 6ap9A-4b9yA:
0.0		 6ap9A-4b9yA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		3 / 3 ARG A 754
ARG A 261
ARG A 685
 None
 1.02A 6bplA-4b9yA:
undetectable
6bplB-4b9yA:
undetectable		 6bplA-4b9yA:
6.56
6bplB-4b9yA:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ILE A 341
ASP A 412
ARG A 463
TRP A 477
PHE A 513
HIS A 540
 None
 0.39A 6c9xA-4b9yA:
35.6		 6c9xA-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ILE A 341
TRP A 410
TRP A 477
PHE A 513
HIS A 540
 None
 0.97A 6c9xA-4b9yA:
35.6		 6c9xA-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ILE A 341
ASP A 412
ARG A 463
TRP A 477
PHE A 513
HIS A 540
 None
 0.40A 6c9xB-4b9yA:
40.2		 6c9xB-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ILE A 341
TRP A 410
TRP A 477
PHE A 513
HIS A 540
 None
 0.97A 6c9xB-4b9yA:
40.2		 6c9xB-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		7 / 12 ILE A 341
ASP A 412
ARG A 463
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.48A 6c9zA-4b9yA:
34.3		 6c9zA-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ILE A 341
ASP A 412
ARG A 463
TRP A 477
PHE A 513
HIS A 540
 None
 0.47A 6c9zB-4b9yA:
35.5		 6c9zB-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ILE A 341
TRP A 410
TRP A 477
PHE A 513
HIS A 540
 None
 1.01A 6c9zB-4b9yA:
35.5		 6c9zB-4b9yA:
24.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ASP A 299
ILE A 341
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 1.32A 6ca1A-4b9yA:
34.4		 6ca1A-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		8 / 12 ASP A 299
ILE A 341
ASP A 412
ARG A 463
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.44A 6ca1A-4b9yA:
34.4		 6ca1A-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ASP A 299
ILE A 341
TRP A 410
TRP A 477
PHE A 513
HIS A 540
 None
 0.87A 6ca1A-4b9yA:
34.4		 6ca1A-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ASP A 299
ILE A 341
ARG A 463
ASP A 480
PHE A 513
HIS A 540
 None
 1.34A 6ca1B-4b9yA:
34.9		 6ca1B-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		8 / 12 ASP A 299
ILE A 341
ASP A 412
ARG A 463
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.42A 6ca1B-4b9yA:
34.9		 6ca1B-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
TRP A 410
PHE A 513
HIS A 540
 None
 0.86A 6ca1B-4b9yA:
34.9		 6ca1B-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		8 / 12 ASP A 299
ILE A 341
ASP A 412
ARG A 463
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.45A 6ca3A-4b9yA:
35.7		 6ca3A-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 12 ASP A 299
ILE A 341
ASP A 480
PHE A 513
HIS A 540
 None
 1.33A 6ca3A-4b9yA:
35.7		 6ca3A-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ASP A 299
ILE A 341
TRP A 410
TRP A 477
PHE A 513
HIS A 540
 None
 0.90A 6ca3A-4b9yA:
35.7		 6ca3A-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		8 / 12 ASP A 299
ILE A 341
ASP A 412
ARG A 463
TRP A 477
ASP A 480
PHE A 513
HIS A 540
 None
 0.46A 6ca3B-4b9yA:
34.5		 6ca3B-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		6 / 12 ASP A 299
ILE A 341
TRP A 410
TRP A 477
PHE A 513
HIS A 540
 None
 0.91A 6ca3B-4b9yA:
34.5		 6ca3B-4b9yA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 6 LEU A 300
TYR A 189
ASP A 509
GLN A 491
 None
 1.39A 6djzC-4b9yA:
undetectable		 6djzC-4b9yA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		5 / 10 GLY A 381
GLY A 380
ASN A 379
ILE A 382
ALA A 372
 None
 1.03A 6e5zA-4b9yA:
undetectable		 6e5zA-4b9yA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B
(Cellvibrio
japonicus) 		4 / 7 ASP A 480
TYR A 189
GLU A 415
GLU A 343
 None
 1.37A 6mn5E-4b9yA:
undetectable		 6mn5E-4b9yA:
8.32